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Cardiovascular Week

Susan Hasty, Publisher

Table of Contents . . . April 25th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cardiovascular Week | Other Publications

Angiology - Invasive MRI is feasible and apparently safe during peripheral angioplasty

Atherosclerosis - LRP1 plays a pathologic function during atherosclerotic lesion progression

Cardioprotection - Nonerythropoietic derivatives may be more effective for treating CV diseases

Hypertension - Majority of hypertensive patients will require combination therapy

Pulmonary Hypertension - Oxidant stress decreases with epoprostenol therapy

Acute Pulmonary Embolism - L-Arginine attenuates APE-induced pulmonary hypertension in rats

Adverse Drug Reaction - Thrombocytopenia can occur in patients receiving clopidogrel and aspirin

Alcohol Use - Alcoholism reduces male heart's ability to synthesize protein

Amyloid Angiopathy - Amyloid-beta deposition studied, aspects in dementia with Lewy bodies clarified

Angiography - Trapidil reduced restenosis in patients treated with balloon angioplasty

Angiology - AT2 may play a role in neuronal blood pressure regulation

Atherosclerosis - Studies describe new findings in atherosclerosis research

Angiology - EGM analysis predicted successful catheter ablution of VT from sinus of Valsalva

Angiology - Manassantin may help prevent atherosclerosis

Angiology - New test measures platelet, coagulation risk factor before thrombotic event

Angiology - Platelet glycoprotein-von Willebrand factor complex studied, effects shown

Angiology - Simultaneous bilateral carotid angioplasty and stenting is feasible

Angiotensin - Angiotensin II analyzed, influence on homeobox expression revealed

Atrial Fibrillation - Research in atrial fibrillation provides new insights

Angiotensin - Angiotensin metabolism pathway suggested to be unrelated to ACE

Angiotensin - PI-PLC beta studied, role in angiotensin-mediated modulation demonstrated

Angiotensin - Study evaluated cardiac effects of angiotensin-(1-7) during ischemia-reperfusion

Arrhythmia - Heart conditions linked to common "hidden" hormone disorders in the elderly

Arterial Disease - Study demonstrates effectiveness of ArtAssist medical device

Asthma - It's not the drugs but the inflammation that increases cardiovascular risk

Cardiology - Researchers provide details of new studies and findings in the area of cardiology

Atherosclerosis - Cranberry juice modulates atherosclerotic vascular dysfunction

Atherosclerosis - Degree of stenosis is only one factor influencing a plaque's tendency to rupture

Atherosclerosis - Endothelial inflammation in insulin resistance reviewed

Atherosclerosis - New findings in the area of atherosclerosis detailed

Atherosclerosis Therapy - Anti-atherosclerotic mechanisms of implitapide elucidated

Cardiology - Studies advance knowledge in cardiology research

Atrial Fibrillation - AF is associated with down-regulation of opioid receptor/ligand expression

Atrial Fibrillation - Automatic wireless home monitoring system provides early AF detection

Atrial Fibrillation - Decremental index may be a new index of vulnerability to paroxysmal AF

Atrial Fibrillation - FDA approves Arctic Front IDE for the treatment of atrial fibrillation

Atrial Fibrillation - Findings in atrial fibrillation provide new insights

Cardiology - Studies describe new findings in cardiology research

Atrial Flutter - Novel cardiac cryoablation system effectively resolves CTI-dependent AFL

Atrial Pacing - Length and contiguity influence specificity of AMS for AF

Autoimmune Disease - Novel immunosuppressant analyzed, effects in autoimmune glomerulonephritis shown

Biochemistry - Study investigated the lifetimes of fluorescent components of matrix NADH

Breast Cancer - Lipid profiling recommended before and after hormonal therapy

Business & Finance - Genetics company reports Q4 net loss of $3,708,000

Hypertension - Reports add new data to hypertension research

Business Update - FDA clears heparin-coated cardiopulmonary bypass blood reservoir

Business Update - New Japanese company set to be strong in neurology and cardiovascular disease

Business Update - Pharmaceutical company changes public accounting firms

Cancer Therapy - Viagra prevents anticancer drug-induced heart damage

Cardiac Arrest - In anoxia, why can't humans be more like western painted turtles?

Cardiac Development -  Xenopus Wnt11-R is the ortholog of mammalian and chicken Wnt11

Hypertension - Researchers provide details of new studies and findings in the area of hypertension

Cardiac Development - Gene studies support common origin of insect dorsal vessel and vertebrate heart

Cardiac Development - Patterns may be helpful in analyzing cell-lineage-based pathological processes

Cardiac Development - Report shows interaction of Tbx5 and Tbx20 in cardiac development

Cardiac Development - Study looked for evidence of polarization in myocardializing cells

Cardiac Hypertrophy - Researchers detail new studies and findings in the area of cardiac hypertrophy

Cardiac Pacemakers - Atrial evoked-response integral can be used to measure lead polarization

Cardiac Pacemakers - Effect of CTOPP on physiologic pacing in Canada determined

Cardiac Pacemakers - Effect of short pulse width programming determined in AutoCapture devices

Cardiac Pacemakers - Novel LV lead can be implanted by guide wire or stylet

Cardiac Pacemakers - Novel biventricular capture verification algorithm developed

Cardiac Pacing - Novel dual-chamber pacing mode minimizes ventricular pacing

Cardiac Resynchronization Therapy - Patients with advanced HF can undergo safe implantations of CRT systems

Cardiac Resynchronization Therapy - Temporal variations in programming of CRT devices characterized

Cardiac Surgery - Proof of the marriage of structure and function happens only with measurement

Cardiac Surgery - Technique identified patients at risk of left heart failure after ASD closure

Cardiology - 2004 was notable for advances in treatment of congenital heart diseases

Cardiology - A1 adenosine receptor deletion limits myocardial tolerance of ischemia

Cardiology - Biphasic shocks are more effective than monophosic in cardioversion of AF

Cardiology - Cardiac MRI is effective to evaluate pretransplant hearts for perfusion defects

Cardiology - Cardiac bedside monitor-defibrillator versus code blue protocol to be studied

Cardiology - Dexamethasone-eluting stents investigated in heart patients

Cardiology - Findings advance knowledge in cardiology research

Cardiology - Government grant to expedite development of stent coating awarded

Cardiology - Inoue balloon and metallic commissurotome are equally effective for PMV

Cardiology - Length of nonsustained ventricular tachycardia predicted of arrhythmic events

Cardiology - MDH1 is overexpressed in LV cardiac muscle of dilated cardiomyopathy patients

Cardiology - Polar 810 s suitable for RR interval measurement during cycle ergometry

Cardiology - Progress brings benefits of revascularization therapy to new groups of patients

Cardiology - QT-interval turbulence occurs with HR turbulence after induced premature beats

Cardiology - Reduced PV diameter after radiofrequency ablation predicts severe stenosis

Cardiology - Sarcalumenin deficiency studied, impaired Ca2+ muscle stores revealed

Cardiology - Secretion of PRA and ANP are affected by atrial size and impaired function

Cardiology - Study examined how systolic loading in nitroglycerin administration affects LV

Cardiology - When it comes to living longer, staying active is key

Cardiomyocytes - Caveolae and caveolin-3 are up-regulated in rat hypertrophied cardiomyocytes

Cardiomyocytes - Interleukin-18 may have a role in inflammatory heart diseases

Cardiomyocytes - Intracellular S100A1 modulates cardiac Ca2+-turnover

Cardiomyocytes - PDGF beta receptor is involved in growth response of rat cardiomyocytes

Cardiomyopathy - CRP has some predictive value in idiopathic dilated cardiomyopathy

Cardiomyopathy - Care must be taken to avoid over-diagnosis of arrhythmogenic RV cardiomyopathy

Cardioprotection - Probucol enhances antioxidant reserve and myocardial energy state

Cardiovascular Devices - Novel radiological landmark can guide axillary vein puncture

Cardiovascular Disease - A disposition toward negative affectivity may be important for CV disease risk

Cardiovascular Disease - Ang II and CRH may be responsible for varying predisposition to CV disease

Cardiovascular Disease - Energy intake reduction crucial for weight loss in metabolic syndrome

Cardiovascular Disease - Lack of uniform method complicates comparisons of endothelial dysfunction

Cardiovascular Disease - PUFAs may have favorable effects on postprandial lipemia

Cardiovascular Disease - Results of collaborative atorvastatin diabetes study reported

Cardiovascular Disease - Review summarizes the role of cytochrome p450 expression in CV disease

Cardiovascular Disease - SSRIs inhibit tight clot formation of platelets in vitro

Cardiovascular Disease Risk Factors - Abdominal fat, high insulin resistance impair metabolic health of older women

Cardiovascular Research - Apelin may have a key role as a paracrine cardiovascular regulator system

Cardiovascular Research - CRF1 may be involved in enhanced sympathovagal antagonism

Cardiovascular Research - Combined growth factors may be superior angiogenesis stimulants

Cardiovascular Research - Ethanol induces hypertension at higher doses by depleting NO and antioxidants

Cardiovascular Research - New findings in cardiovascular described

Cardiovascular Research - Nitroxidergic activation of nucleus tractus solitarii may involve sGC.

Cardiovascular Research - Study explored role of CRP as a modulator of inducible nitric oxide synthase

Cardiovascular Research - Study investigated how level of ventilation influences CV response to hypoxemia

Cardiovascular Research - Superoxide generation induced by angiotensin II infusion may be mediated by ET-1

Cardiovascular Surgery - Novel technique enables replacement of heavily calcified mitral annuli

Carotid Stenting - Emboli-prevention devices provide better protection than GPIs

Catalase - Smooth muscle nitric oxide synthase studied, catalase potentiation revealed

Chagas Disease - Institute announces new hope for Chagas disease treatment

Chronic Renal Failure - Children with chronic renal failure display blunted and ultradian CV rhythms

Circulation - Cannabinoids show opposing vascular effects in rat aorta.

Clinical Trials - Enrollment begun for embolic protection device in carotid clinical trial

Collaborations - Alliance to develop new treatment of heart and vascular diseases

Collaborations - Pharma companies announce drug discovery and development collaboration

Colon Cancer - Predictors of atrial fibrillation after elective surgery for colorectal cancer

Complementary & Alternative Medicine - No ECG parameter was an independent predictor of plasma ANP concentration

Complementary & Alternative Medicine - Omega-3 fish oil infused with plant phytosterols said to reduce cholesterol

Congenital Heart Defects - High-resolution imaging systems allow doctors to see inside embryonic heart

Congenital Heart Disease - Article reviews MRI/MRA and CT exams for diagnosis of congenital heart disease

Congestive Heart Failure - A kidney transplant can reverse heart failure

Congestive Heart Failure - Heart assist device company files for CE Mark approval to market LVAS in Europe

Coronary Artery Bypass - Trial of drug for preventing coronary artery bypass graft failure initiated

Coronary Artery Bypass Grafting - Biatrial pacing after CABG improves hemodynamics and prevents AF

Coronary Artery Disease - Impaired vasodilation mediated by reactive oxygen species

Coronary Artery Disease - Increasing BMI improves outcome of stenting for coronary artery disease

Coronary Stenting - Noncardiac surgery within 6 weeks carries high MACE risk

Cystatin - Cystatin C deficiency studied, effects in apolipoprotein E-null mice revealed

Diabetes Pathogenesis - Apple-shaped women up to 6 times more likely to develop diabetes, physician says

Diabetes Therapy - Acarbose prevents cardiac ischemia injury caused by hyperglycemia

Diabetes Therapy - Prevention and treatment of hypertension in diabetes reviewed

Diabetic Nephropathy - High sympathetic activity, low adiponectin predict poor outcomes

Diabetic Nephropathy - Researchers describe findings in diabetic nephropathy studies

Diagnostics - 3D ultrasound is useful for assessing the severity of a fetal defect

Diagnostics - Cardiac marker provides additional clinical value

Diagnostics - Multi-center study on cardiac imaging system ready for patient evaluations

Diagnostics - Stress ECG has distinct diagnostic advantages after PTCA

Diagnostics - Study provides data about risk of abnormal karyotype after fetal AVSD diagnosis

Diet & Nutrition - Mechanism underlying soy phytoestrogen's cardioprotective effects elucidated

Diet & Nutrition - Study finds health benefits of cocoa flavanols

Diet & Nutrition - Tests: Most B vitamins of high quality but three lacking in ingredients

Dilated Cardiomyopathy - Cardiac resynchronization therapy induces reverse LV remodeling

Electrophysiology - Circadian variations and sex-related differences occur in QT dynamics

Endocrinology - Absence of heme oxygenase-1 exacerbates myocardial injury in diabetic mice

Endothelial Dysfunction - ROS leads to elevated levels of p22phox and sustained ROS generation

Endothelium - Sedentary life of lab mice does not lower endothelial function

FGF Signaling - FGF signaling may promote efficient interaction of mesoderm with ectoderm

Finance - Biopharma company announces net loss of $0.10 per share for the year

Finance - Disease management company announces improved financial results

Finance - Medical products company secures $10.1M financing

Finance - Photoselective medicine company announces financial results

Finance - Tennessee-based branded pharmaceutical company reports Q4, year end 2004 results

Fitness - Heart disease patients can lower cardiovascular risk factors with exercise

Fitness - Moderate aerobic exercise improves cardiovascular and nervous system function

Fitness & Wellness - Fitness council suggest low-fat diet, exercise program for shaping up

Genetics & Genomics - Study investigated proximate downstream effectors of Notch signaling

HIV/AIDS-Related Dyslipidemia - HAART reduces VLDL and IDL apoB catabolic rate in patients with dyslipidemia

Heart Devices - FDA approves 2000 FlowMaker pivotal trial

Heart Disease Therapy - Lower-cost heart drugs could help expand treatment to millions of Americans

Heart Failure - A large variety of heterogeneous conditions cause heart failure in children

Heart Failure - Akt signaling pathway contributes to signaling events in pacing-induced HF

Heart Failure - Biomolecules and mechanisms for control of cardiac remodeling must be defined

Heart Failure - Hemodynamic improvement during BiV stimulation depends upon optimal AVD and VVD

Heart Failure - Improvements conferred by CRT can be matched by a bifocal RV system

Heart Failure - Metoclopramide has antinatriuretic effects only in HF patients

Heart Failure - Poly(ADP-ribos)ylation is important in pathogenesis of banding-induced HF

Heat Shock Protein - Heat shock protein inducer examined, ischemic neuroprotective effect shown

Hematology - Polymers demonstrate a significant decrease in platelet adhesion

Hepatic Encephalopathy - Portal hypertension-based rat model suitable for study

Hormone Replacement Therapy - Findings in hormone replacement therapy provide new insights

Hormone Replacement Therapy - HRT doesn't affect 24-hour heart rate variability in postmenopausal women

Hypertension - Findings show diuretics work better for high blood pressure

Hypertension - Heavy drinkers twice as likely to have high blood pressure

Hypertension - Increased superoxide anion contributes to hypertension

Hypertension - Recent studies add new data to hypertension research

Hypertension - Remodeling with diuretic-beta-blockade may contribute to long-term CV protection

Hypertrophy - Adrenomedullin may participate in cardiac hypertrophic remodeling

Imaging - CT and MR datasets allowed interchangeable use of volumetric analysis tools

Imaging - California hospital updates cath lab with new 3D soft-tissue imaging technology

Imaging - Flat panel detector systems can be used in cone-beam computed tomography scanner

Imaging - Hybrid CT-PET moves into mainstream of routine oncologic and CV imaging

Imaging - Multisegment image reconstruction improves temporal resolution in MDCT

Imaging - Research add new data to imaging body of knowledge

Imaging - Scanner manufacturer proceeds with international cardiac CT study

Imaging - Semiautomated analysis of cardiac CT allows for RV functional analysis

Implantable Cardioverter Defibrillators - AutoCapture compatible with dual-coil ICD leads

Implantable Cardioverter Defibrillators - Dual-chambered pacing may increase tachyarrhythmia incidence

Implantable Cardioverter Defibrillators - Novel algorithm enables automatic identification of ICD lead dysfunction

Implantable Cardioverter Defibrillators - Pre-discharge defibrillation testing not needed for state-of-the-art ICDs

Infective Endocarditis - Infective endocarditis in India occurs in relatively younger population

Inflammation - Platelet P-selectin studied, requirement in allergic inflammation clarified

Information Technology - Solution manages patient-identifiable supplies to improve line margins

Ischemia - Hippocampus analyzed, post-ischemic protein disulfide changes revealed

Ischemia - Study investigated mechanisms regulating AMPK phosphorylation in ischemic hearts

Ischemia/Reperfusion - New findings in ischemia/reperfusion described

Kidney Disease - Patients with chronic kidney disease are a very high risk for CV disease

Legal Issues - Maker of low perfusion pulse oximetry wins antitrust lawsuit against Tyco

Liver Cancer - Tamponade led to death after radiofrequency ablation of liver carcinoma

Magnetic Resonance Imaging - Routine breath-hold gradient echo-MRI is accurate for cardiac diagnostics

Medical Devices - Continuous noninvasive blood pressure monitoring system introduced

Medical Devices - FDA approval granted for new ECG technology

Medical Devices - Twenty-five year study of bileaflet prosthetic heart valve published

Mental Health - Salivary alpha-amylase may be a reliable marker of psychosocial stress

Mergers & Acquisitions - Acquisition agreement for developer of stroke prevention technology executed

Myocardial Infarction - Different patterns of recovery may affect risk-stratifying of post-MI patients

Myocardial Infarction - Differential heart attack risks among blacks, whites remain mystery

Myocardial Infarction - Inflammatory response involving leucocytes plays a role in pathogenesis of MI

Myocardial Infarction - MI without heart failure impairs endothelium-dependent relaxation

Myocardial Infarction - Women with heart attacks benefit from stenting

Nanotechnology - Synthetically designed nanocarriers mimic properties of glycosaminoglycans

Neuroscience - Protein sigma1s contributes to reovirus pathogenesis and virulence

Organ Transplantation - No single approach alone is likely to address the need for organ replacement

Osteoporosis - Data show postmenopausal women in hormone study increased bone density

Osteoporosis - Recent findings in osteoporosis described

Pacemakers - Security system simulator to test pacemaker compatibility developed

Patient Education - Hospital educates women on heart disease risks, increases use of services

Pediatric Cardiology - Study examined autonomic regulation in premature low-birth-weight infants

Peptides - CART peptide fragment 55-102 may excite neurons in intermediolateral cell column

Peripheral Arterial Disease - Angioplasty prevents amputation in severe peripheral arterial disease

Peripheral Arterial Disease - Article reviews evidence for use of ACE inhibitors in patients with PAD

Peripheral Arterial Disease - First drug-eluting stent implant for leg artery blockage performed at Stanford

Personnel - Craig J. Hartley, PhD, rejoins company's scientific advisory committee

Personnel - Electronic medical transcription company adds member to board

Personnel - Medical company designates presiding director after death of CEO

Personnel - Pharmaceutical company names Jerry Okikawa senior director, product development

Pharmaceutical Research - Study examined mechanisms of beta blockade effects on platelets

Polycystic Ovary Syndrome - Women with PCOS are at increased risk for cardiovascular disease

Preeclampsia - New findings in preeclampsia described

Preventive Medicine - Employee benefit trust fund introduces campaign to encourage healthy living

Proteomics - Results contrast with the current perception of IL-6 receptor activation

Pulmonary Hypertension - Statins, other cholesterol depletors, may disrupt hypertension development

Purinoceptor - ATP-stimulated ANP release through P1 receptor subtype

Renal Disease - Angiotensin II expands VEGF production in response to renal injury

Renal Failure - Blood pressure control is very effective in retarding renal disease progression

Reperfusion - Study examined mechanisms of red palm oil improvement of reperfusion function

Reproductive Biology - Reports advance knowledge in reproductive biology research

Restenosis - Valsartan after stent implantation reduces restenosis compared to ACE inhibitors

Smooth Muscle - Corticotropin-releasing factor receptor studied, regulation clarified

Smooth Muscle - Staurosporine studied, inhibition of K+ coronary muscle cell current shown

Stem Cell Research - Stem cell activation sustains hereditary hypertrophy in cardiomyopathy

Stem Cell Transplantation - Cidofovir treats polyomavirus nephropathy in heart and SCT recipients

Stem Cells - Trial studying adult mesenchymal stem cells on heart attack victims announced

Stroke - First U.S. patient enrolled in ACT I clinical trial

Surgical Technology - European clinical study of adhesion barrier for use in cardiac surgery initiated

Thrombosis - Alcohol-free red wine prevents arterial thrombosis in rats

Thyroid Function - Paper reviews relationship between thyroid function and hemostatic disorders

Tissue Engineering - Fibrin used as cell carrier in cardiovascular tissue engineering applications

Tobacco Use - Pharma company welcomes news of Medicare coverage of smoking cessation

Toxicology - Venom of two related box jellyfish contain different lethal components

Transplant Medicine - Heart transplant patients benefit from new technology, easier monitoring

Transplant Medicine - Longest surviving artificial heart patient marks 5 years on miniature device

Transplant Medicine - New national record set for organ transplants

Transplant Medicine - New technology, new approach to help heart, lung patients awaiting transplants

Transplant Medicine - Nitrite says NO to ischemia/reperfusion injury

Transplant Medicine - Solution for perfusion and flushing of donor pancreata given U.S. FDA approval

Type 2 Diabetes - CAD alters ventricular repolarization dynamics in diabetes patients

Vascular Graft - FDA approves device to treat descending thoracic aneurysms

Vascular Smooth Muscle - Vascular triacylglycerol accumulation studied, pathways defined

Venous Thromboembolism - Strategies can improve identification and prophylaxis rates

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