Diabetes Therapy

Acarbose prevents cardiac ischemia injury caused by hyperglycemia

Published in Cardiovascular Week, April 25th, 2005

The alpha-glucosidase inhibitor acarbose prevents the increase in cardiac ischemia/reperfusion injury caused by repeated postprandial hyperglycemia.

According to recent research published in the FASEB Journal, "Protective effects of the alpha-glucosidase inhibitor acarbose have been reported for various diabetic complications. In the STOP-NIDDM study, even patients without overt diabetes, but with impaired glucose tolerance, had a reduction in cardiovascular events when treated with acarbose. Therefore, we investigated the effect of repetitive postprandial hyperglycemia on the cardiac ischemia/reperfusion injury in vivo."

"Mice were treated...

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Source: Cardiovascular Week (2005-04-25)

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