Acute Pulmonary Embolism
L-Arginine attenuates APE-induced pulmonary hypertension in rats
Published in Cardiovascular Week, April 25th, 2005
"L-Arginine is a substrate for nitric oxide (NO) synthesis and produces pulmonary vasodilatory effects in patients with pulmonary hypertension and in hypoxic animals," according to scientists in Brazil, who "hypothesized that L-arginine would attenuate the increase in oxidative stress and the pulmonary hypertension" associated with APE.
"Using an isolated lung perfusion rat model of APE," D.C. Souza-Costa and colleagues at the University of Sao Paulo "examined whether L-arginine (0, 0.1, 0.5, 3, and 10 mmol/L) attenuates...
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Source: Cardiovascular Week (2005-04-25)
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