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Cardiovascular Week

Susan Hasty, Publisher

Table of Contents . . . May 9th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cardiovascular Week | Other Publications

Atherosclerosis - Thrombophilic risks are increased in patients with carotid atherosclerosis

Cardiovascular Research - AVT's attenuation of crowding-induced aggression is modulated by a CV mechanism

Cardiovascular Research - Arterial compliance and heart rate have combined effect on aortic pulse pressure

Diet & Nutrition - Daily variety of fruits and vegetables reduce risk of chronic diseases

Matrix Metalloproteinases - Selective MMP-13 inhibitors exhibit no detectable activity against other MMPs

ACE Polymorphism - Carriers of D/D, D/I genotypes had less cognitive benefit after shunt surgery

Adriamycin - Saeng-Ji-Hwang analyzed, protective effect on cytotoxicity revealed

Adverse Drug Reaction - Fetal abnormalities linked to sartan use in last 6 months of pregnancy

Androgen Receptors - Androgen receptor variant modulates AR function

Anesthesia - Anesthetics differ in depression of basal and beta-adrenergic stimulated state

Aneurysm - Endovascular therapy may be beneficial for some patients with cerebral aneurysms

Angiology - Studies advance knowledge in angiology research

Angiology - CE Mark granted for three sizes of paclitaxel-eluting coronary stent system

Angiology - Data on assays to discover anti-angiogenic agents for cancer treatment presented

Angiology - Recent findings illuminate research in angiology

Angiology - Review focuses on the molecular basis for atherosclerotic plaque instability

Angiology - sICAM-1 levels may predict progression of carotid atherosclerosis

Cardiology - Recent findings illuminate research in cardiology

Angiotensin - Control of sympathetic outflow to kidney is under control by brain AT II

Aortoiliac Arteriosclerosis - Aggressive cholesterol lowering does not delay progression

Arteriosclerosis - Endothelial nitric oxide synthase lessens carotid artery lesion formation

Arthritis - Common painkillers plus acid-reducing drugs safer, cost-effective for arthritis

Atherosclerosis - Findings describe new data in atherosclerosis research

Atherosclerosis - LDL size and subclasses are markers of atherosclerosis in type 2 diabetes

Cardiology - Recent studies add new data to cardiology research

Atherosclerosis - Lesion development reveals complex role for CD4 in atherosclerosis

Biomaterials - Clotting time shortened for HUVECs cocultured with biomaterial-treated monocytes

Business Update - Carotid stent delivery system gets CE mark

Business Update - Delphi inks agreement to integrate and market new cardiac technology

Business Update - Pharma company extends Lescol promotion agreement with Novartis

Business Update - Public relations firm selected to execute campaign for women's heart health

Cardiology - Reports advance knowledge in cardiology research

CHARGE Syndrome - Multidisciplinary approach is essential in assessment and management of CHARGE

CHARGE Syndrome - Research provides insights into prognosis and special needs of CHARGE patients

Cardiac Hypertrophy - Article reviews developments regarding cardiotrophic kinases

Cardiac Surgery - Humidified CO2 reduces surgical wound desiccation

Cardiac Transplantation - Myocardial performance index is abnormal in long-term heart transplant receivers

Cardiology -  wa3 mutant mice may be a model for analyzing inflammation in heart disease

Cardiology - Researchers report details of new studies and findings in the area of cardiology

Cardiology - 5-HT plays a critical role in the control of vagal outflow to the heart

Cardiology - AI-700 phase III trials expanded after U.S. FDA meeting

Cardiology - A2A ARs activation is needed to trigger KATP/NO-dependent hyperemia

Cardiology - Anatomical structure of isthmus between vena cava and tricuspid annulus varies

Cardiology - Article focuses on the torsadogenic properties of antipsychotics

Cardiology - C4d studies may predict cardiac allograft vasculopathy after transplantation

Hypertension - Recent findings illuminate research in hypertension

Cardiology - CREM may be a key regulator of cardiac morphology, function, and gene expression

Cardiology - Cardiac MRI has a bright future for research in small animals

Cardiology - Data advance knowledge in cardiology research

Cardiology - Device company announces success of surgical ablation system

Cardiology - Fetal bradycardia and AV block may be missed if assessed only at birth

Cardiology - IGF-1 improves the functional and structural integrity of failing hearts

Hypertension - Researchers describe findings in hypertension studies

Cardiology - Improved efficiency correlated with increase in fetal CK isoenzyme expression

Cardiology - Independent studies substantiate biocompatibility of stent coating technology

Cardiology - Isoflurane should be maintained at minimum required for stable sleep

Cardiology - Miami purchases AEDs for police vehicles under citywide PAD program

Cardiology - NHE inhibitors may attenuate acute responses to MI and chronic postinfarction

Cardiology - PARP activation contributes to disturbances in response to doxorubicin exposure

Imaging - Researchers' work adds to imaging body of knowledge

Cardiology - Removal of N-terminal extension of cardiac troponin I enhances cardiac function

Cardiology - Study Pax3 expression in rat embryos or fetuses exposed to nitrofen

Cardiology - U.S. FDA grants approval of Liberte coronary stent system

Cardiomyocytes - High glucose causes a rise in [Ca2+]I in neonatal cardiac myocytes

Cardioprotection - Preischemic administration of trimetazidine protects against I/R injury

Cardioprotection - Pyrroloquinoline quinone is a highly effective cardioprotective agent

Cardiopulmonary Bypass - Intestinal mucosal barrier function during CPB characterized

Cardiopulmonary Bypass Surgery - Prolonged CPB increases risk of neutrophil-mediated BBB damage

Cardiovascular Devices - Novel microaxial blood pump provides short-term mechanical support

Cardiovascular Research - Cardiologist peers inside fetal hearts to discover congenital disease causes

Cardiovascular Research - Excess postexercise O2 use was similar for continuous and interval exercise

Cardiovascular Research - HR variability and breathing rate variability are mutually independent

Cardiovascular Research - Heart rate increased, heart rate variability decreased with fast ascent

Cardiovascular Research - High salt intake may inhibit the rostral ventrolateral medulla

Cardiovascular Research - Kallikrein gene transfer protects cardiac cells after ischemia-reperfusion

Cardiovascular Research - Knowing role of KATP in CV system will help to regulate cell metabolism

Cardiovascular Research - Personality covariates modestly affect relation between drinking and CV health

Cell Research - Study examined properties of mitochondria in muscle lacking creatine kinase

Central Hypoventilation Syndrome - Cold pressor stimulation demonstrated cerebellar and medullary influences

Central Hypoventilation Syndrome - Structures that can alter respiratory timing are deficient in CCHS

Cerebral Ischemia - FDA approves treatment for cerebral vasospasm

Chlamydia Pneumoniae - Antibiotic treatment does not reduce risk of secondary cardiac events

Chronic Kidney Disease - Link between inflammation, oxidation, and calcifications merits attention

Clinical Trials - Research technology company to provide services to 2 drug developers for studies

Collaborations - Agreement signed with Quadrant for development of Ventavis

Complementary & Alternative Medicine - Study results show form of soy and fish oil may help prevent heart attacks

Congenital Heart Disease - Management of heart patients' gynecologic health outlined

Congestive Heart Failure - Cardiologist to convene panel to assess data for acute heart failure drug

Congestive Heart Failure - Genes influence how heart failure patients respond to drugs

Congestive Heart Failure - Heart failure drug associated with higher risk of death in first month

Congestive Heart Failure - Heart failure patients sought for study evaluating implantable pulse generator

Congestive Heart Failure - Pharmaceutical company, QLT USA to develop congestive heart failure treatment

Congestive Heart Failure - Study sought to inhibit aldosterone synthase for treatment of congestive HF

Coronary Artery Bypass - Enrollment begins in trial comparing drug-eluting stents to cardiac surgery

Coronary Artery Bypass - Positive results reported in coronary artery bypass study

Coronary Artery Bypass - Presentation made on CardioPass graft to Brazilian surgeons

Coronary Artery Bypass Grafting - Benefits of epidural anesthesia for CABG surgery determined

Coronary Artery Bypass Grafting - Novel technique improves IABP timing during off-pump CABG

Coronary Artery Disease - Changes in immune response to cytomegalovirus are a compounding factor in CAD

Coronary Artery Disease - Clinical trial comparing drug-eluting stents, cardiac surgery enrolling subjects

Coronary Artery Disease - HRT, antioxidant vitamins don't improve endothelial vasodilator function

Deep Vein Thrombosis - Diagnosis and treatment of deep vein thrombosis reviewed

Diabetes Therapy - Improved postprandial glycemic control does not improve vascular risk

Diabetic Cardiomyopathy - Effects of streptozotocin on ventricular myocytes investigated

Diabetic Cardiomyopathy - Sodium-calcium exchange in action potential of diabetic heart examined

Diagnostics - 20 MicroTip assays for sale on the VITROS 5,1 FS Chemistry System

Diagnostics - Cholesterol diagnostic company announces sales milestone

Diagnostics - Gallium-67 SPECT useful for detection of prosthetic valve infection

Diagnostics - Quantix ND provides accurate ultrasonic measure of cerebral blood flow

Diagnostics - U.S. FDA grants clearance for new Microvolt T-Wave Alternans device

Diet & Nutrition - Adding avocado fruit can significantly enhance carotenoid absorption from food

Diet & Nutrition - Antioxidants seem suited to reduce CV events by improving endothelial function

Diet & Nutrition - Article summarizes in vivo studies on protective effects of green tea catechins

Diet & Nutrition - Benefits of modulating potassium balance in CV patients

Diet & Nutrition - Effects of recommended diet elements are mediated by different mechanisms

Diet & Nutrition - Study links ester-E compound to reduction in cholesterol

Diet & Nutrition - U.S. food market poised for whole grains, high fiber trend, report says

Diet and Nutrition - New study demonstrates cardioprotective effects of Protykin

Disease Associations - C-reactive protein studied in dialysis patients

Drug Delivery - Encapsulation reverses the adverse effects of therapeutic cell implantation

Drug Development - Studies indicate cholesterol lowering efficacy of dispersed cellulose technology

Drug Development - Trial data presented for type 2 diabetes, high cholesterol therapies

Drug Research - Sulfated polysaccharides potentiate the effects of angiogenic growth factors

Echocardiography - Researchers detail new studies and findings in the area of echocardiography

Electrocardiography - Earliest ECG showing ventricular preexcitation can be dated back to 1909

Electrocardiography - Measurement of premature ventricular beats by ECG warrants renewed attention

Emergency Medicine - Data from British public access defibrillators analyzed

End-Stage Renal Disease - Variety of factors contribute to CV disease in children with ESRD

Endocrinology - Amenorrhea in female athletes is associated with endothelial dysfunction

Endocrinology - Estrogen receptors mediate the protective effects of red wine phenol

Enzymology - Partial tissue kallikrein deficiency leads to arterial dysfunction

Finance - Medical device company files form 10-KSB, reports acquisition of MedQuest

Finance - Nanocoated coronary stent maker raises $3 million

Fitness - Fatness, despite fitness, is linked with cardiovascular risk factors

Gene Transfer - Adeno-associated virus serotype 8 overcomes barriers to vector dissemination

Generic Drugs - Report: Generic competition threatens the maturing statin market

Genetics & Genomics - Allele confers marked homozygous disadvantage for HDL-C, SBP, stroke, longevity

Heart Disease Risk - Cardiovascular risk factors have declined substantially over past 40 years

Heart Failure - Atorvastatin therapy improved endothelial function in heart failure patients

Heart Failure - Ca2+ abnormalities contribute to progression of heart failure

Heart Failure - Chicago man implanted with the HeartMate II LVAS

Heart Failure - Chicago man receives new heart-pump device

Heart Failure - Modulating gene expression is a potential therapeutic approach for heart failure

Heart Failure - Phase II study launched evaluating use of implantable pulse generator

Heart Failure - Studies show promise for defining genetic and acquired causes of heart failure

Hematology - PentaLyte phase II clinical trial begins

Hematology - Serum markers herald thrombosis risk in patients with relapsed myeloma

Hormone Replacement Therapy - HRT shouldn't be recommended solely to prevent cardiovascular disease

Hypertension - Ambulatory blood pressure monitoring is recommended in varied circumstances

Hypertension - Canadian doctors under-prescribe older and cheaper yet effective drugs

Hypertension - Data limitations impede assessment of role of hypertension in heart failure

Hypertension - Drinking wine or beer has same result: higher blood pressure

Hypertension - Gender differences in blood pressure and heart rate compared in rat models

Hypertension - New data illuminates research in hypertension

Hypoxia - Hypoxia at key points causes differential effects on organ development

Imaging - Article provides sodium images of the mouse heart

Imaging - Mice can be studied in high-field MR systems positioned vertically for 3 hours

Imaging - New imaging system that sheds light on coronary bypass surgery used at Stanford

Imaging - Planimetry offers a simple, noninvasive method to quantify aortic valve stenosis

Imaging - Researchers' data advance imaging research

Infectious Diseases - Effects of antibiotic studied in CAD patients with C. pneumoniae

Infectious Diseases - Infection with C pneumoniae may be more severe in old animals

Intravenous Fluids - Stewart's approach provides framework for design of fluids for acid-base effects

Ischemia - Prevalence of ischemia in Turkish patients with type 2 diabetes reported

Ischemia - Proteins in highly soluble fraction may contribute to cardioprotection

Ischemic Mitral Regurgitation - Common mechanism of ischemic mitral regurgitation is Carpentier IIIb dysfunction

Kidney Transplantation - Adenosine increase may be relevant for anti-ischemia and tissue protection

Legal Issues - Companies announce co-promotion, manufacturing, settlement agreements

Lipid Studies - Effect of L162V polymorphism on plasma TG and apoC-III depends on dietary PUFA

Lipoproteins - Lipoprotein lipase examined, effect on aortic atherosclerosis revealed

Lipoproteins - Very low density lipoproteins studied, role as secretory vector revealed

Liver Cancer - Case of juvenile hepatocellular carcinoma with liver cirrhosis reported

Low Birth Weight - Researchers identify marker of heart disease in babies

Lung Cancer - Decision for thoracic surgery in elderly requires careful assessment

Medical Devices - Defibrillator company upgrades cardiac devices with V-V timing programmability

Medical Devices - In-office systems to assess heart and blood vessels introduced at meetings

Medical Devices - Lek Pharmaceuticals donates funds for the purchase of defibrillators in Slovenia

Mergers & Acquisitions - Clearance given by German cartel office to acquire CTI Molecular Imaging, Inc.

Mergers & Acquisitions - Companies merge to create broad-based European cardiovascular biotech company

Mergers & Acquisitions - Pharma company acquires 51% stake in Heartview

Metabolic Syndrome - New definition of metabolic syndrome released

Myocardial Infarction - Left atrial volume is higher in patients not treated with reperfusion

Myocardial Infarction - MRIs for assessing perfusion, function, viability are ready for clinical use

Myocardial Infarction - Melbourne researchers develop safer and more effective "aspirin"

Myocardial Infarction - New findings in myocardial infarction described

Myocardial Infarction - Obesity adds risk of heart disease in siblings with family history

Myocardial Infarction - Sodium nitrite gets new medical uses for heart attack and organ damage

Myotonic Dystrophy - Study provides a molecular mechanism for myotonic dystrophy heart pathology

Neuroscience - Cardiac voltage-gated Na+ channels are targets of the neurotoxin BmK I

Neuroscience - Emotional stress alters arterial vascular endothelial growth factor expression

Neuroscience - Researchers report details of new studies and findings in the area of neuroscience

Neuroscience - Review describes how the brain transforms signals into differential output

Pediatric Cardiology - Cardiac sympathetic activity may be lower in preterm infants

Periodontal Disease -  P. gingivalis gingipains studied, influence in periodontal disease defined

Peripheral Arterial Disease Risk Factors - Treatment of peripheral arterial disease must include modifying CV risk factors

Peripheral Arterial Occlusive Disease - Anti-C. pneumoniae treatment inhibits PAOD progression

Personnel - Gordon Snyder named VP of sales at device company

Personnel - Judge rules hospital committed unfair labor practice in Washington nurses case

Personnel - Pharma company appoints member to board

Philanthropy - AEDs awarded to schools in nationwide contest

Protein Recombination - A new recombinant apolipoprotein E variant has improved biological functions

Proteomics - Longer atrial fibrillation duration is associated with CRP elevation

Proteomics - RGS proteins, regulators of CV physiology, are potential drug targets

Proteomics - apo A-IV-2 allele is associated with slightly reduced plasma triglyceride levels

Psychosomatic Medicine - Happiness related to biological function

Pulmonary Medicine - Combined cell and gene therapy remedies pulmonary hypertension

Radiology - Monitoring of radiological doses is recommended for radiologists, cardiologists

Receptor Studies - Alpha1B -AR leads to changes in pathway associated with hypertrophic response

Regulatory Issues - Patients' lives at risk from substandard drugs, say heart specialists

Restenosis - Intravascular gene transfer reduces neointima formation in denuded aortas

Restenosis - Women benefit from drug-eluting stents as much as men

Stroke - FDA approves HYZAAR to help prevent stroke in those with hypertension and LVH

Stroke - eNOS stimulates reparative growth factors following cerebral ischemia

Surgical Technology - Patient enrollment for ENDEAVOR IV trial of drug eluting stents commences

Thromboembolism - Research urgently needed to treat blood clots in children

Transplant Medicine - Data: CyIS improves long-term survival in lung-transplant patients

Vascular Stents - Resorbable biocompatible stent coating releases restenosis inhibitor

Venous Thromboembolism - ProC Global screening test predicts recurrent VTE

Ventricular Hypertrophy - Collagen synthesis increases with hemodynamic load in a reversible manner

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