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Cardiovascular Week

Susan Hasty, Publisher

Table of Contents . . . July 25th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cardiovascular Week | Other Publications

Arrhythmia - Calmodulin kinase II activity critical for atrioventricular nodal conduction

Arrhythmia - Use of ACE inhibitors and ARBs in the prevention of AF needs further study

Cardiac Arrhythmia - Catheter ablation improves QOL of patients with paroxysmal atrial fibrillation

Cardiomyopathy - Increased H-FABP indicates ongoing myocardial damage in HC patients

Ischemia - Hyperoxygenation may be critical triggering factor for postischemic remodeling

Acute Coronary Syndrome - EARLY ACS trial designed to reinforce benefit of early use of Integrilin

Amyotrophic Lateral Sclerosis - Study falls short of showing efficacy of high dose vitamin E therapy

Anesthesia - Clonidine is a safe and effective alternative to epinephrine in oral surgery

Anesthesia - I.V. anesthetics restore cerebral autoregulation; volatile anesthetics do not

Angina Pectoris - Broader vasopeptidase inhibition is required to alleviate chronic angina

Angiology - Recent findings illuminate research in angiology

Angiology - Reports advance knowledge in angiology research

Angiology - Right axillary artery cannulation works for extracorporeal membrane oxygenation

Angioplasty - Estrogen attenuates vasoconstriction during angioplasty

Angiotensin - Angiotensin type analyzed, receptor antagonist activity documented

Aortic Arch Aneurysm - Novel Matsui-Kitamura stent grafting technique shows promise

Aortic Arch Surgery - Near infrared spectroscopy detects flow alterations during ACP with hypothermia

Atherosclerosis - Research in atherosclerosis provides new insights

Aortic Arch Therapy - Ascending-to-descending aortic bypass via right thoracotomy is safe

Aortic Stenosis - Analytical model describes instantaneous pressure gradient across aortic valve

Arrhythmia - Electroanatomic mapping linked to high rate of ablation success

Arrhythmia - Ibutilide is effective at terminating atrial arrhythmias

Arrhythmia - Researchers reveal mechanisms underlying catecholaminergic VT

Arrhythmia - Respiratory sinus arrhythmia reflects cardiorespiratory interaction

Cardiology - New findings in the area of cardiology described

Arterial Bypass Surgery - Surgical management of groin lymphatic complications reviewed

Atherosclerosis - ACAT2 is a therapeutic target for CHD associated with hypercholesterolemia

Atherosclerosis - Apoptotic cell phagocytosis studied, impairment in atherosclerosis noted

Atherosclerosis - Endothelin studied, role in and nature of CD40 induction defined

Atherosclerosis - MRI shows statin therapy shrinking plaques

Atherosclerosis - New research in the area of atherosclerosis detailed

Cardiology - Researchers publish new studies and findings in the area of cardiology

Atherosclerosis - Novel blood test measuring oxidized fats is heart disease indicator

Atherosclerosis - Pioglitazone has anti-atherosclerosis activity in diabetic patients

Atherosclerosis - Proatherogenic events and cell adhesion studied, role of redox state clarified

Atrial Fibrillation - Ablation close to the esophagus can lead to heating at the esophageal lumen

Atrial Fibrillation - Anti-inflammatory therapy may decrease AF incidence after cardiac surgery

Hypertension - Recent findings in hypertension provide new insights

Awards - Sensation 64 CT system wins gold in 2005 Medical Design of Excellence Award

Benign Prostatic Hyperplasia - Alpha(1)-AR antagonists should be first-choice treatment option

Blood Pressure - Beta-1 adrenoceptor blockade mediates the cardiovascular effects of khat chewing

Business Update - Chinese health authority approves sale of latest line of Powerheart AEDs

Business Update - Definitive proxy statement filed for acquisition of MedQuest

Business Update - U.S. FDA panel: AbioCor submission did not yet meet HDE standards

Hypertension - Researchers detail new studies and findings in the area of hypertension

Calcific Aortic Stenosis - Intensive lipid-lowering therapy does not stop progression of stenosis

Cardiac Arrest - Nonpatient cardiac arrest needs better management at hospitals

Cardiac Arrhythmia - Cardiac resynchronization therapy not recommended for right bundle branch block

Cardiac Arrhythmia - Ventricular therapies, QOL, mortality assessed in ICD patients

Cardiac Catheterization - Fluoroscopic localization of the femoral head is a useful landmark

Cardiac Hepatopathy - Cardiac hepatopathy before and after heart transplantation is benign

Hypertension - Researchers publish new studies and findings in the area of hypertension

Cardiac Hypertrophy - Changes in 11HSD1 and 11HSD2 expression not associated with cardiac hypertrophy

Cardiac Myxoma - Caspase-3-dependent apoptosis in cardiac myxoma not associated with HPV or EBV

Cardiac Pacemakers - Closed loop stimulation pacing effective in young patients

Cardiac Pacemakers - Exercise has different autonomic effects on sinus and AV node

Cardiac Pacemakers - Learning curve of laser lead extraction elucidated

Cardiac Pacemakers - Techniques for improving outcome of LV lead placement evaluated

Imaging - Reports add new data to imaging research

Cardiology - Daniel A. Pelak appointed president and CEO

Cardiology - Medical technology company initiates patent foramen ovale closure study

Cardiology - New findings in cardiology described

Cardiology - Progress reported in pig studies of stent coating in preparing for trials

Cardiology - Protein kinase C examined, role in neonatal cardiac structure clarified

Imaging - Researchers describe findings in imaging studies

Cardiology - Spray nitroglycerin brings fast relief for angina

Cardiology - Thrombospondin-1 buffers non-affected tissues following myocardial infarction

Cardiology - U.S. FDA grants approval to market pacemakers

Cardiopulmonary Bypass - Antioxidant defence during on-pump CABG characterized

Cardiopulmonary Bypass - Long-term renal replacement therapy post cardiopulmonary bypass is not likely

Imaging - Studies advance knowledge in imaging research

Cardiovascular Disease - Company awarded major clinical research program in cardiovascular disease

Cardiovascular Disease - FM-VP4 toxicity study complete

Cardiovascular Disease - Researchers report details of new studies and findings in the area of cardiovascular disease

Cardiovascular Disease Risk Factors - Polymorphisms associated with fibrinogen levels found in Spanish population

Cardiovascular Disease Risk Factors - Standard lipid profile predicts LDL particle size in high-risk black population

Cardiovascular Interventions - Defect closure with Amplatzer septal occluder effective after 5 years

Cardiovascular Interventions - Percutaneous device closure effective for interatrial septal defects

Cardiovascular Surgery - Aortic connector may raise risk of saphenous vein graft occlusion

Cardiovascular Surgery - Research demonstrates potential of TMR Plus gene therapy

Carotid Artery Stenting - No difference between embolic protection devices for carotid artery stenting

Cerebral Artery Infarction - PCA infarction stimulates MCA infarction more often than previously thought

Cerebral Embolism - Patients with AF and dense SEC at high risk for cerebral embolism

Cerebral Palsy - Study reveals CP pathophysiology differs from that of acute hypoxia-ischemia

Cesarean Delivery - Role of volume preloading in Caesarean section anesthesia clarified

Chagas Disease - Heart rate turbulence methodology is best for detecting autonomic alterations

Chronic Heart Failure - Biopharmaceutical company reports results of treatment for chronic heart failure

Chronic Heart Failure - Carvedilol improves left ventricular diastolic function in advanced CHF

Chronic Kidney Disease - Anemia and LVH predict cardiovascular disease in CKD patients

Chronic Total Coronary Occlusion - Frontrunner coronary catheter effective for recanalization

Cirrhosis - Brain natriuretic peptide has prognostic value in cirrhosis progression

Cirrhosis - Terlipressin provides better hemodynamic effects than somatostatin

Clinical Trials - Agreement signed to deliver cardiac safety services to Japanese trial market

Clinical Trials - Recombinant human thrombin clinical trial results presented at meeting

Coronary Artery Bypass - Cardiopulmonary bypass linked to post-CABG aspirin resistance

Coronary Artery Bypass - Perioperative RBC transfusion linked to heightened mortality risk

Coronary Artery Disease - Findings describe new data in coronary artery disease research

Coronary Artery Disease - Lacidipine reduces common carotid artery IMT, decreases inflammatory markers

Coronary Artery Disease - Technical advances improve myocardial imaging in women

Coronary Heart Disease - High-density lipoproteins subclasses associated with heart disease

Coronary Heart Disease - Hormones found to play equivocal role in coronary heart disease

Defibrillation Therapy - Medical adhesive and/or ePTFE improve lead extraction

Depression - Prospective study data suggest depression is a cardiac risk factor

DiGeorge Syndrome - Characteristic gene expression determined via microarray analysis

Diabetes - TNF-alpha may be a risk for coronary heart disease among diabetics

Diabetes Pathogenesis - Studies advance knowledge in diabetes pathogenesis research

Diabetic Nephrology - Phase 3, phase 4 clinical program of therapy for diabetic nephropathy initiated

Diagnostics - LDX System receives CRMLN certification

Diagnostics - Recent findings in diagnostics described

Diagnostics - Study shows Coronary Calcium Score most accurate test for heart attack risk

Diet & Nutrition - Low total vitamin C plasma level is risk factor for hemodialysis patients

Disease Associations - Carotid plaques examined, role of LDL humoral immune response defined

Disease Associations - Endocarditis studied, fibrinogen and fibronectin cooperative binding revealed

Drug Delivery - First patient receives TRT with Benephit Delta Infusion System

Drug Development - Phase III study to evaluate first-in-class drug to treat cardiogenic shock

Echocardiography - Researchers' findings advance echocardiography research

Electrocardiographic Interpretation - Most physicians cannot recognize a long QT when they see one

Embryonic Stem Cell Research - TGF-beta 2 enhances cardiac myocyte differentiation from embryonic stem cells

Emergency Medicine - Chest pain response to sublingual nitroglycerin doesn't predict cardiac origin

Endocytosis - Studies describe new findings in endocytosis research

Endothelial Dysfunction - Na+/H+ exchanger linked to endothelial dysfunction induced by high glucose

Environmental Health - Study aims to determine if air pollution accelerates heart disease

Epicondylitis - Low dose shock wave therapy without local anesthesia is safe

Epilepsy - Recent findings in epilepsy provide new insights

Fetal Medicine - Real-time 3-D fetal echocardiography using matrix probe is feasible

Finance - Company focused on morbid obesity management reports plan for private placement

Finance - Pharmaceutical company completes $5.9 million stock offering

Gastroesophageal Reflux Disease - GERD rises in frequency in Singapore

Gene Research - Gene studies reveal the complexity of mouse apolipoprotein B gene expression

Grants - Canadian company awarded NSERC grant to develop cholesterol-lowering platform

Hantavirus - Researchers find novel peptides that inhibit entry by SNV and HTNV

Heart Attack Risk Factors - Metabolic syndrome increases risks of heart attack and mortality

Heart Disease Risk Factors - Cost-effectiveness of nutritional counseling for obese patients discussed

Heart Failure - Family education and support interventions are necessary to heart failure care

Heart Failure - Heart failure patients sought for study evaluating implantable pulse generator

Heart Failure - U.S. FDA approves BiDil for treatment of heart failure in black patients

Heart Organogenesis - Embryonic disturbance of cell adhesion molecules can result in cardiac defects

Heart Transplantation - Renal function, compliance are long-term complicating factors in children

Heart Transplantation - Risk factors for severe post-transplant right heart failure identified

Heart Valve Surgery - EuroSCORE predicts in-hospital and long-term mortality after heart valve surgery

Hodgkin Lymphoma - Novel chemotherapies for Hodgkin lymphoma being investigated

Hormonal Therapy - Appropriate use of hormones reduces risk of comorbidities

Hormones - Researchers' findings advance hormones research

Hypercholesterolemia - Bad cholesterol: genes make the difference scientific

Hypercholesterolemia - Berberine may be a useful alternative to statins for lowering cholesterol

Hypercholesterolemia - New gene-scanning technology marks a major advance in disease research

Hypercholesterolemia - Patients with ApoE epsilon 4 allele have higher lipid peroxidation levels

Hypercholesterolemia - Statin therapy can briefly raise risk of psychiatric disturbances

Hypertension - BMI changes between ages 5 and 14 affect blood pressure at age 14

Hypertension - Effects of weight loss on long-term hypertension outcomes reviewed

Hypertension - Enzyme affects hypertension by controlling salt levels in body

Hypertension - Findings in hypertension provide new insights

Hypertension - Normal blood pressure could add years to your life

Hypertension - Once-a-day diltiazem HCL is effective and safe against hypertension

Hypertension - Pharma company receives nonapprovable letter from U.S. FDA for PW2101

Hypertriglyceridemia - Bezafibrate is effective in ameliorating atherogenic dyslipidemia

Imaging - Companies form partnership to resell imaging visualization and analysis software

Imaging - Lower-priced multi-functional cardiac ultrasound system introduced

Imaging - Marketing authorization recommended for contrast agent, Vasovist

Imaging - New data illuminates research in imaging

Imaging - North Shore University Hospital installs CT imaging system

Imaging - Radiology service to provide subsecond 64-slice CT scanner

Imaging - T2-weighted CMR with gadolinium enhancement is useful in myocarditis patients

Insulin Resistance - Arterial stiffness related to insulin resistance in hypertensive older adults

Interventional Cardiology - Canadian researchers call for more angiograms

Ischemia - Delayed subendocardial thinning suggests early stage hypoperfusion

Ischemia - GGA blunts the endothelial dysfunction induced by ischemia and reperfusion

Ischemia - Ketotifen inhibits I/R induced leukocyte adhesion and can prevent organ damage

Ischemic Heart Disease - Assessment of myocardial viability reviewed

Ischemic Heart Disease - Imaging study reveals characteristics of ischemic human myocardium

Laparoscopic Surgery - Utility of post-discharge thromboprophylaxis evaluated

Left Ventricular Function - Cardiac MDCT compared with angiocardiography

Lipolysis - Sympathetic modulation by carvedilol and losartan reduces lipolysis

Lipoproteins - New data illuminates research in lipoproteins

Liver ischemia - Getting the NAC preserves aortic functions following liver ischemia-reperfusion

Malaria - Fatty meals have no effect on the relative oral bioavailability of piperaquine

Medical Devices - Aortic mini-root-containing valves studied, endothelial seeding described

Mesenteric Ischemia - Techniques to reduce GI complications in heart surgery patients are needed

Mitral Valve Replacement - Postoperative free-floating left atrial ball thrombus reported

Multiple Organ Failure - N-acetylcysteine treatment has no prophylactic use

Myocardial Infarction - Adenosine, at a particular dose, may help patients with STEMI

Myocardial Infarction - Antidepressants may lower risk of recurrent heart attack, death

Myocardial Infarction - Aspirin underprescribed to prevent heart attack and stroke

Myocardial Infarction - Bone marrow cells have a minor hand in myocardial healing after infarction

Myocardial Infarction - Nitroprusside is an effective treatment of no-reflow phenomenon

Myocardial Ischemic Reperfusion Injury - Na+/Ca2+ inhibitors may have therapeutic potential

Myotonic Dystrophy Type 1 - Cytosine-thymine-guanine repeat length is only one factor in progression of DM1

Nonacute Coronary Artery Disease - Meta-analysis finds no benefit in PCI versus conservative therapy

Nutrition - Anti-inflammatory effect may help explain fish benefit

Obesity Pathogenesis - Activity restriction owing to heart disease increases obesity risk

Obstetrics - Interleukin-6 may elevate fetal nucleated red blood cells

Oxygen Saturation - Cerebral TOI may not be reliable in detecting low SjO2 in children

Parkinson Disease - Only cardiac MIBG uptake can distinguish PD from multiple system atrophy

Patents - Catheter, medical tubing securement development company announces 7 new patents

Patient Safety - Hemashield Vantage peripheral vascular grafts recalled

Percutaneous Coronary Intervention - Enoxaparin shows similar results as unfractionated heparin during PCIs

Percutaneous Coronary Intervention - Patients undergoing PCI at risk for retroperitoneal bleeding

Percutaneous Coronary Intervention - Plasma PAI-1 levels may identify patients with late restenosis risk

Peripheral Artery Disease - Distal protection devices improve safety of lower extremity treatment

Personnel - Diagnostic imaging company names Robb Young senior manager, cardiology CT

Personnel - Kelly W. Elliott, RN, named VP of clinical affairs by medical devices company

Personnel - Molecular diagnostic technology company announces new leadership team

Physical Fitness - Exercise capacity reduced in patients with glycogen storage disease type I

Platelets - Reports add new data to platelets research

Post-Traumatic Stress Disorder - Intense terrorism does not affect PTSD symptoms

Postural Tachycardia Syndrome - Acute acetylcholinesterase inhibition improves tachycardia in POTS

Product Licensing - Company obtains license from Valentis for novel drug formulation technology

Professional Education - Medical training facility opens in Columbus, Ohio

Professional Education - Provider of testing services, nuclear cardiology certification board join forces

Prognostics - CRP plus ECG ST-segment depression predicts mortality

Public Health - Health indicators helped define public health priorities

Pulmonary Medicine - Epidural block - isoflurane/nitrous oxide combo okay for lung resection

Pulmonary Medicine - Mechanism for PV focal firing that converts to atrial fibrillation found

Pulmonary Medicine - Researchers use MRI to characterize proximal pulmonary artery blood flow

Pulse Oximetry - Normal values of pulse oximetry in newborns is lower at high altitudes

Renal Graft - Tacrolimus improves serum lipid levels and improves cardiovascular risk

Renal Transplantation - BP, arterial wall properties altered after cyclosporine to tacrolimus switch

Restenosis - Recent findings in restenosis provide new insights

SARS - Tachycardia reported in patients recovering from SARS

ST Elevation Myocardial Infarction - NOGA useful in assessing post-PCI myocardial recovery

Saphenous Vein Grafts - Clinical outcomes after sirolimus-eluting stent implantation are good

Shock - Profound hypothermia preserves cognitive functions in a swine model

Statins - Reports advance knowledge in statins research

Stem Cell Research - Company provides update on hESC at stem-cell meeting

Stroke - Protein kinase C delta inhibitors attenuate injury and improve outcome

Stroke - U.S. FDA grants clearance to market blood test for assessing risk of stroke

Strokes - Cerebral endothelial ICAM-1 expression analyzed, aprotinin effect shown

Surgical Technology - Paper analyzes effects of modernizing care for patients undergoing major surgery

Tissue Engineering - Umbilical vein scaffold developed for cardiovascular tissue engineering

Total Arch Replacement - Arch-first technique improves neurological outcomes for total arch replacement

Tracheostomy - There are no clinical differences between open versus bedside PDT

Transplantation Medicine - Aggressive organ donor management increases amount of organs available for use

Transplantation Medicine - PaO2 <250mmHg is not a definite contraindication for lung transplantation

Ventricular Hypertrophy - Strategies that decrease ET-1 can improve coronary endothelial dysfunction

Weight Loss - Reasons for intentional and unintentional weight loss in older men outlined

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