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Allergy & Immunology

Epinephrine caused increase in CV responses in allergic adults

Published in Cardiovascular Week, August 15th, 2005

Researchers have investigated cardiovascular responses in patients with acute allergic reactions treated with parenteral epinephrine.

According to investigators in the United States, "[Our] present study describes the cardiovascular responses to epinephrine (Epi) given into the arm, in adult patients with acute allergic reactions, and the differential responses to subcutaneous (SC) and intramuscular (IM) administration."

R.Y. Lin and colleagues of St. Vincent's Hospital in New York explained, "Sixty-three adult patients were treated with Epi administered SC or IM after H-1 and H-2 receptor blockade. Heart rate and blood pressure (BP) were then...

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