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Cardiovascular Week

Susan Hasty, Publisher

Table of Contents . . . September 12th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cardiovascular Week | Other Publications

Coronary Artery Bypass - Criteria indicate angiography subsequent to coronary artery bypass grafting

Coronary Artery Disease - Youngest CAD patients had the poorest health related quality of life

Heart Rate Variability - HRV biofeedback can augment vagal heart rate regulation

Statins - Short-term LDL reduction improves peripheral endothelial function

Stroke - Asthma may be an independent risk factor for incident stroke

Acute Coronary Syndrome - Inflammatory markers may be associated with myocardial injury

Acute Coronary Syndrome - National statistics for incidence of acute coronary syndrome may not be accurate

Adenovirus - Vascular muscle cell RNA turn-over examined, PDGF-BB regulatory role defined

Aging - Study finds age-related changes of bradykinin receptors in the heart

Alzheimer Disease - New research suggests heart bypass surgery increases risk of Alzheimer disease

Angiography - Multislice CT angiography can reduce invasive angiography

Cardiology - Researchers describe findings in cardiology studies

Angiology - PROGRESS-AMS Study completes enrollment

Angiology - Recent findings in angiology provide new insights

Angiology - Study found no correlation between platelet activation and angiographic severity

Angioplasty - Baseline LV function is a predictor of survival after primary angioplasty

Angiotensin - Ang II does not have role in norepinephrine release and LV hypertrophy

Angiotensin - Angiotensin III analyzed, effect on pituitary on tyrosine kinase defined

Imaging - Researchers' findings advance imaging research

Angiotensin - Aortic smooth muscle contraction examined, sevoflurane effects defined

Angiotensin - Variants of RAS components are thought to affect inherited HT

Antioxidants -  Glossogyne tenuifolia studied, antioxidant activity revealed

Antioxidants - Antioxidant defenses are important before onset of hypoxia

Imaging - Researchers' work adds to imaging body of knowledge

Arteriosclerosis - Phase II clinical trial of MLN1202 initiated

Atherosclerosis - C-reactive protein is early indicator of stiffened arteries

Atherosclerosis - MCA atherosclerosis plaques may be more stable than carotid plaques

Atherosclerosis - Studies report links between ferritin levels and atherosclerosis

Atrial Fibrillation - European CE Mark for ultrasound ablation system announced

Atrial Natriuretic Peptide - Researchers dissected the endothelium-mediated actions of ANP in vivo

Imaging - Studies add new findings to imaging body of knowledge

Awards - Vascular surgery device developer named to Deloitte Technology Fast 50 Program

Biomedical Engineering - Cytochrome c oxidase NO catabolism studied, involved factors clarified

Breast Cancer - Breast cancer treatment may increase mortality from other diseases

Business & Finance - Business development corporation announces change of auditor

Business & Finance - Human genetics-focused biopharmaceutical company reports Q2 2005 results

Business & Finance - Medical devices group reports Q1 2006 results, marketing of drug-eluting stent

Imaging - Studies describe new findings in imaging research

Business Update - Mobile medical technologies developer moves to Over the Counter Bulletin Board

Business Update - Oxycom oxygen delivery monitor unveiled

COX-2 - Combining fatty acids with COX-2 inhibitors will prevent thrombotic CV events

Cardiac Hypertrophy - Relationship of NF-kappaB activity and cardiac remodeling is causal

Cardiac Rehabilitation - Lifestyle change is important but complex during rehab after MI

Cardiology - Intensive relaxation practice enhances recovery from ischemic cardiac events

Cardiology - Journal articles compare clinical benefits of coronary stents

Cardiology - New research in the area of cardiology detailed

Cardiology - Rate of aortic regurgitation is higher in patients taking pergolide

Cardiology - Revascularization recommendations were similar for blacks and whites

Cardiology - Thoracic, cardiac surgeons join health benefits provider to gather clinical data

Cardiomyocytes - Na+ channels contribute to the action potential of cardiomyocytes

Cardiomyocytes - Trilinolein inhibits beta MyHC promoter activity and hypertrophy

Cardioprotection - Research in cardioprotection provides new insights

Cardiopulmonary Resuscitation - CPR technique may be used in any microgravity environment

Cardiopulmonary Resuscitation - Study investigated prognostic value of several markers after CPR

Cardiovascular Disease - Combined nicotinic acid/statin is an innovative approach to reducing CHD risk

Cardiovascular Disease - Researchers detail new studies and findings in the area of cardiovascular disease

Cardiovascular Disease - Therapy for vascular disease in diabetic patients reviewed

Cardiovascular Disease Risk Factors - Should ethnicity be considered when evaluating cardiovascular risk for women?

Cardiovascular Regulation - Study examined relationship between CV regulation and brain activation

Cardiovascular Research - K-Ras protein has a unique role in cardiovascular homeostasis

Caseous Calcification - Caseous calcification of the mitral annulus diagnosed

Cerebrovascular Circulation - PKG activation is mechanism of permissive action of NO and prostacyclin

Chronic Kidney Disease - Uremia may have a permissive effect for cardiovascular damage

Clinical Trials - Cancer-focused biosciences company updates U.S. NCI-sponsored clinical trials

Collaborations - Mayo Clinic and tech company cooperate to validate cardiovascular risk test

Complementary & Alternative Medicine - Green tea prevents cell invasion and matrix degradation

Congenital Central Hypoventilation Syndrome - Neuroanatomic deficiencies suggest a structural basis for CCHS

Congenital Heart Disease - Higher recurrence CHD among dizygotic twins may depend on an unidentified risk

Congenital Heart Disease - Murine t-box transcription factor TBX20 mutation linked to cardiomyopathies

Coronary Artery Bypass - Long-term outcomes after coronary artery bypass grafting prove worse for women

Coronary Artery Bypass - Stem cells with heart bypass surgery trial to begin

Coronary Artery Disease - ABCA1 and SR-BI modulation may have potential for treating CAD

Coronary Artery Disease - Aged garlic extract may improve impaired endothelial function

Coronary Artery Disease - Haptoglobin phenotype was associated with attenuated heart rate variability

Coronary Artery Disease - No difference was found between stenting and surgery in rate of events

Coronary Bypass Surgery - Stress recovery index aids in predicting outcome after coronary bypass surgery

Coronary Heart Disease - Patients with CHD have higher expression of HO-1 in heme oxygenase-1

Critical Care Medicine - 17beta-estradiol has a critical dosing effect on neuronal survival

Critical Care Medicine - Noninvasive monitoring is feasible for prospective therapy evaluation

Cryopreservation - Antibiotic carryover may be harmful during heart valve freezing

Depression - Heart failure patients show brain injury linked to depression

Diabetes Epidemiology - Socio-economic inequalities in diabetes in Basque Country reported

Diagnostics - Noninvasive method is accurate for measuring stroke volume and cardiac output

Diagnostics - Researchers' data advance diagnostics research

Diet & Nutrition - High doses of Vitamin E were required to affect experimental atherosclerosis

Diet & Nutrition - Lipoprotein profiles modified by very low-carbohydrate diets

Diet & Nutrition - New report on soy finds limited evidence for health outcomes

Diet & Nutrition - Review examines how different dietary constituents may interact

Disease Control - Report describes success of community-based heart health interventions

Drug Development - Company focused on cocrystallography adds rennin to portfolio

Drug Development - Emerging roles of apelin in biology and medicine reported

Drug Development - Thelin marketing authorization application accepted for review by EMEA

Drug Safety - European agency recommends marketing approval for COX-2 inhibitor be withdrawn

Echocardiography - Researchers describe findings in echocardiography studies

Endocrinology - Studies advance knowledge in endocrinology research

Environmental Health - Exposure to concentrations of PM2.5 and O3 increases diastolic BP

Essential Fatty Acids - Derivatives of essential fatty acids can modify a number of disease states

Exercise - Aerobic exercise reduces triglycerides in overweight and obese adults

Finance - Conseco closes private offering of convertible debentures

Finance - Cryotherapy company reports Q3 operating revenue of $11.1 million

Finance - Medical technology company recorded $2.690 billion first quarter 2006 revenues

Finance - Neuroprotection-focused company arranges $6.2 million financing

Finance - Pharma company reports net loss of $8.0 million for fourth quarter 2005

Finance - Pharmaceutical development company announces net loss of $4.9 million

Finance - Regenerative medicine company reports Q2 revenues of $1,541,000

Finance - Stent technology development company closes second round of financing

Fitness & Wellness - Dyspnea and leg effort are the major symptoms limiting exercise

Fitness & Wellness - Researchers further extol the benefits of exercise

Gene Research - Fast microarray platform for profiling expression of gene set released

Gene Research - Maker of gene analyzer systems launches quality control kit for RNA analysis

Genetics & Genomics - Alzheimer disease mediates link between apo E genotypes and mortality

Genetics & Genomics - Mutations in LMNA gene may disrupt cardiomyocyte organization

Genetics & Genomics - Myocardial Gata4 has role in regulating cardiomyocyte proliferation

Genetics & Genomics - Nutrigenetics assessments sold direct to consumers available in some pharmacies

Genetics & Genomics - Review examined studies linking IHD with polymorphisms of MHC molecules

Genetics & Genomics - Vitamin C may merit close scrutiny for the treatment of heart disease

HIV/AIDS Pathogenesis - HIV-1 Tat induces VCAM-1 expression in pulmonary artery endothelial cells

Healthcare Access - Blue Cross of Idaho offers new diabetes, asthma, heart failure services

Heart Disease - Studies describe new findings in heart disease research

Heart Failure - Chagas disease was main prognostic factor for mortality in heart disease cohort

Heart Failure - Findings describe new data in heart failure research

Heart Failure - Increases in mitral regurgitation identify HF patients at risk

Heart Failure - New heart failure guidelines stress early diagnosis and treatment

Heart Surgery - Aprotinin plus cell salvage effectively lowers transfusion needs

Hemodialysis - Direct infectious burden does not coincide with serum burden in HD patients

Heparin-Induced Thrombocytopenia - Rate of HIT in hemodialysis patients comparable to other populations

Histamine - Study investigated whether histamine induces TF expression in vascular cells

Homocysteine - Folic acid supplementation does not influence hemostasis markers

Hydroxyurea - Hydroxyurea therapy used for sickle cell disease in community-based practices

Hypercholesterolemia - Ezetimibe with simvastatin treatment enabled more patients to reach LDL-C target

Hypercholesterolemia - Fibrates have no influence on platelet function within 1 month of therapy

Hyperhomocysteinemia - Hcy homeostasis is regulated independently of PEMT localization

Hypertension - Common painkillers linked to high blood pressure in women

Hypertension - Doxazosin exhibits beneficial effects on lipid profile

Hypertension - New type of hypertension treatment shows promise

Hypertension - Positive results reported for phase 2b trial in resistant hypertension treatment

Hypertension - Pulmonary arterial smooth muscle cell VEGF expression studied, increase defined

Hypertension - Salt-induced hypertension is not mediated by endothelial dysfunction

Hypertension Therapy - New concepts in blood pressure-lowering in diabetes reviewed

Imaging - 64-slice CT is highly accurate for assessing coronary artery stenosis

Imaging - Changes in heart mass and volume linked to left ventricle problems

Imaging - Data advance knowledge in imaging research

Imaging - Strain rate imaging may be accurate for recognition of ischemic myocardium

Ischemia - Cellular death in hippocampus studied

Ischemia - Ischemic injury studied, effects on chronic damage in renal grafts revealed

Ischemia - Skeletal muscle studied, effect of ischemia/reperfusion on CXC chemokine defined

Ischemia - Stroke neuroprotection assessed, role of AMP-activated protein kinase clarified

Ischemia-Reperfusion - Results underscore importance of studying the naive microcirculation

Ischemic Heart Disease - Uptake of 99mTc-Sestamibi can be useful in investigating myocardial viability

Magnetic Resonance Imaging - Mathematical model accurately quantifies resting myocardial blood flow

Medical Devices - Company announces U.S. FDA clearance and U.S. launch of extraction catheter

Medical Devices - Device for treatment of atrial septal defect approved for marketing in Japan

Medical Devices - U.S. FDA grants humanitarian use approval for balloon catheter.

Medical Devices - U.S. launch of 2-lumen catheters for measuring arterial pressures announced

Mergers & Acquisitions - Healthcare services company acquires Medcon Ltd.

Mergers & Acquisitions - Technology company completes merger and equity financing

Myocardial Infarction - Bone marrow cells effects are insufficient for regeneration after MI

Myocardial Infarction - Databases may not accurately estimate risk of MI in naproxen, ibuprofen users

Myocardial Infarction - Race and sex disparities in heart attack care, survival not improving

Myocardial Infarction - Studies describe new findings in myocardial infarction research

Myocardial Infarction - Study examined frequency of C1019T polymorphism of connexin37 in AMI patients

Neuroscience - Hypothalamo-hypophyseal examined, salusin and vasopressin association revealed

Nutrition & Health - ECG characteristics were not affected by dietary n-3 fatty acids

Nutrition & Health - Food behavior established in childhood may track into adulthood

Nutrition & Health - Pyridoxine availability may be needed to reduce hyperhomocysteinemia

Nutrition & Health - Vitamin deficiencies may aggravate risk of CAD in Pakistani population

Paclitaxel - Study finds Taxus has lower MACE rate than Cypher

Patient Counseling - Generally, counseling practice is targeted for wrong people, wrong time

Pediatric Cardiology - Novel surgical technique facilitates infant ICD implantation

Peptides - Elevated BNP levels may be common pathway for many CV pathologic states

Percutaneous Coronary Intervention - PCI complication rate is dependent on clinical presentation of patients

Peripheral Vascular Disease - Studies find possible drug targets for improving vascular health

Personnel - Maker of cardiovascular assist devices announces management transition

Personnel - Medical device company announces new position for its chairman and CEO

Personnel - Venture capital fund names managing director

Philanthropy - Financial group foundation funds women's heart luncheon, youth education program

Proteomics - Myocyte growth examined, nature of regulation clarified

Proteomics - Recombinant PLB and SLN suitable for high-resolution structural studies

Pulmonary Hypertension - Blockade of EGFR signaling may be strategy to reverse pulmonary arterial HT

Pulmonary Hypertension - Company completes European Union process for pulmonary hypertension treatment

Quality Assurance - Identification of ICU errors can lead to quality improvement

Respiratory Failure - Practice variation for bilevel NIV exists among specialties

Restenosis - Studies describe new findings in restenosis research

Sleep Apnea - Obstructive sleep apnea syndrome affects left ventricular diastolic function

Statins - Statins and proteasome inhibitors do not have common action

Stents - Head-to-head comparisons must address differential efficacy of stents

Stress - Acute stress reactivity may not be independent of stressful life events

Stroke - Researchers uncover genetic link to stroke after heart surgery

Thrombolysis - Report gives overview of technical approaches to ultrasound thrombolysis

Thrombosis - Elderly persons have a high risk of thrombotic events

Tissue Engineering - Studies add new findings to tissue engineering body of knowledge

Tobacco Use - Damage caused by smoking may include advanced interstitial pneumonitis

Tobacco Use - Second-hand smoke costs U.S. economy $10 billion annually, actuary study shows

Tobacco Use - Surgeon general comments on KFC and Pizza Hut restaurants' smoking bans

Transplant Medicine - Researchers' findings advance transplant medicine research

Vasovagal Syncope - Increased baroreflex latency may predispose to vasovagal syncope

Verapamil - Analysis confirms that overall findings of CONVINCE study are robust

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