Published in Cardiovascular Week, September 12th, 2005
The amendments are being made in response to 5 patients that showed EKG changes without clinically significant consequences after infusion of 17-AAG.
With the amended protocols, clinical investigators will obtain electrocardiograms prior to treatment with 17-AAG or DMAG and after infusion in the initial cycle of therapy. The protocol amendments will also exclude patients with certain histories...
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