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Cardiovascular Week

Susan Hasty, Publisher

Table of Contents . . . November 14th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cardiovascular Week | Other Publications

Blood Clotting - Coagulation system is activated in Duchenne muscular dystrophy patients with cardiac dysfunction

Hypertension - Elevated pulmonary arterial pressure suspected as a predictor for hypertension

Hypertension - Protective role for diastolic blood pressure evident in normal population

Sedation - Adverse cardiovascular events observed during respiratory sedation of pediatric patients

Acute Coronary Syndrome - Gender differences identified in treatment of women with ACS in Irish population

Aging - Plasma total cholesterol is affected by age-dependent genetic influences

Anemia - Levels of a hematopoiesis inhibitor partially explain anemia in heart failure

Aneurysms - Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection

Aneurysms - Diverticula of Kommerell and aberrant subclavian arteries complicated by aneurysms

Angiography - Research in angiography provides new insights

Angiography - Researchers detail new studies and findings in the area of angiography

Angiology - C-reactive protein elevation correlates with accelerated atherogenesis in rheumatoid arthritis

Angiology - Cerebral oxygen balance is impaired during repair of aortic coarctation in infants and children

Angiology - Computed tomography is of limited diagnostic value in evaluating CAD

Angiology - Coronary artery stenoses detected using multi-detector computed tomography

Angiology - Flow cytometry of platelet-leukocyte aggregates may permit monitoring of platelet function

Cardiology - New findings in the area of cardiology described

Angiology - Flow-mediated vasodilation predicts the presence and extent of coronary artery disease

Angiology - Hybrid surgical/endovascular treatment shows promise

Angiology - Impedance monitoring alone is insufficient during catheter ablation of atrial fibrillation

Angiology - Neovascularization prevails in acute venous thrombosis

Angiology - New data illuminates research in angiology

Angiology - Nitric oxide is critical in maintaining vasodilator tone in the llama fetus

Cardiology - New research in the area of cardiology detailed

Angiology - Phenylephrine increases blood flow in the radial artery used as a coronary bypass conduit

Angiology - Prevention efforts reduce hepatitis B virus-associated polyarteritis nodosa cases

Angiology - Sex difference in vascular injury response related to AT2 receptor expression

Angioplasty - Re-188-labeled stents reduce intimal hyperplasia in a rabbit model

Angiotensin - Simvastatin therapy normalizes sympathetic neural control in experimental heart failure

Apoptosis - Ceramide activates a mitochondrial p38 mitogen-activated protein kinase

Cardiology - Researchers describe findings in cardiology studies

Atherosclerosis - New findings in atherosclerosis described

Atherosclerosis Vaccine Development - Chimeric enzyme vaccine attenuated atherosclerosis in rabbit model

Atrial Fibrillatiion - Decision to use anticoagulant therapy must take gender into consideration

Body Composition - Ultrasonography is used to evaluate visceral fat and metabolic syndrome

Brachial Artery Pseudoaneurysm - Aneurysm resection with revascularization by axial anastomosis effective for drug abusers

Business & Finance - Cardiovascular drug discovery company completes $31.9 million financing round

Cardiology - Researchers detail new studies and findings in the area of cardiology

Business & Finance - Cardiovascular-focused drug discovery company reports Q1 2006 financial results

Business & Finance - Gene-based company announces plan to sell myoblast cell therapy program

Cancer Therapy - Lymphoma patients with advanced disease and poor prognosis require intensified treatment

Cardiac Devices - Universal dual-chamber ICD implantation is cost-effective

Cardiac Resynchronization Therapy - Impedance cardiography enables noninvasive AV-interval optimization

Cardiac Surgery - Artificial PTFE chordae effective for treating anterior mitral leaflet prolapse

Cardiology - Researchers report details of new studies and findings in the area of cardiology

Cardiac Surgery - Malleable surgical ablation probe receives U.S. FDA 501(k) clearance

Cardiac Surgery - New approach to antiplatelet therapy during coronary interventions under study

Cardiac Transplantation - Researchers detail new studies and findings in the area of cardiac transplantation

Cardiology - Are over-the-counter cold medicines safe for your heart?

Cardiology - Basis of paroxysmal atrial fibrillation can be predicted by gender and left atrial enlargement

Cardiology - Catheter ablation sites identified in patients with ventricutar tachycardia

Cardiology - Researchers' data advance cardiology research

Cardiology - Findings advance knowledge in cardiology research

Cardiology - Hepatocyte growth factor gene therapy blunts vascular remodeling in hypertrophic hearts

Cardiology - Idiopathic restrictive cardiomyopathy in children requires prompt diagnosis

Cardiology - Ischemia in peri-infarct viable myocardium is associated with apoptosis

Cardiology - Ischemic preconditioning and cardioplegia differentially affect myocardial energy metabolism

Cardiology - Linear ablation lesion strategy is safe for noninducible or nonsustained tachycardia

Cardiology - Studies add new findings to cardiology body of knowledge

Cardiology - Non-cardiac QTc-prolonging drugs increases the risk of sudden cardiac death

Cardiology - Noncontact mapping enables ventricle endocardial electrical restitution

Cardiology - Partial cricotracheal resection is useful for pediatric subglottic stenosis

Cardiology - Public AED use by NCAA universities has good long-term cost effectiveness

Coronary Artery Bypass - Researchers publish new studies and findings in the area of coronary artery bypass

Cardiology - Rate-control yields better prognosis than rhythm-control in patients with atrial fibrillation

Cardiology - Small fiber muscle mechanoreceptors act to inhibit cardiac vagal tone to produce tachycardia

Imaging - Findings describe new data in imaging research

Cardiology - Study shows Hedgehog pathway protects and preserves heart muscle function

Cardiology - Viagra blunts the effects of stress on the human heart

Cardiology - Walking and sports linked with heart health benefits in Japan

Cardiomyopathy - Arrhythmogenic right ventricular cardiomyopathies have common pathway

Cardiomyopathy - Combined cell therapy benefits severely ischemic hearts in canine models

Imaging - Researchers' work adds to imaging body of knowledge

Cardiovascular Disease - Analysis suggests Cypher Stent more cost effective than bypass surgery

Cardiovascular Disease - People lower on the socio-economic scale are less likely to get treatment to prevent heart disease

Cardiovascular Disease - Phase 1 study underway of rFXIII for patients undergoing cardiac surgery

Cardiovascular Disease - Radical approach to cardiac resynchronization shows promise

Cardiovascular Research - Prostacyclin protects against elevated blood pressure and cardiac fibrosis

Cardiovascular Risk Factors - Olive and sunflower oil blend decreases estimate of 10-year cardiovascular risk

Imaging - Studies add new findings to imaging body of knowledge

Childhood Obesity - Findings describe new data in childhood obesity research

Childhood Obesity - Weight loss improved the cardiovascular risk profile in obese children

Chronic Heart Failure - Flow-mediated vasodilation predicts outcome in patients with chronic heart failure

Clinical Trials - Clevidipine phase 3 program resumes, phase 3 interim data affirms safety profile

Clinical Trials - Clinical trials data show excellent long-term safety, efficacy of stent system

Clinical Trials - Complete clinical, angiographic data confirm patient safety of drug-eluting stent

Ischemia - Recent findings illuminate research in ischemia

Clinical Trials - Data from four studies finds multiple overlapping stents better for high-risk patients

Clinical Trials - Stent system clinical trial shows reduction of restenosis in diabetic patients

Collaborations - DirectDesign Discovery collaboration inked with KAI Pharmaceuticals

Congenital Heart Disease - Spatio-temporal image correlation is valuable in diagnosing complex congenital heart diseases

Coronary Artery Bypass - Data: FilterWire EZ Embolic Protection System reduces major adverse cardiac events

Coronary Artery Bypass - New data illuminates research in coronary artery bypass

Coronary Artery Bypass - On-pump CABG associated with poor endothelial progenitor cell function

Coronary Artery Disease - L-Arginine bolsters angiogenic response in hypercholesterolemia models

Coronary Heart Disease - Fair treatment in the workplace is associated with a reduced risk of coronary heart disease

Diabetes Complications - Statins reduce the risk of heart disease in diabetic patients with chronic kidney disease

Diabetic Nephropathy - Irbesartan plus perindopril needed to reduce aldosterone, proteinuria, and TGF-beta1

Diagnostics - Myocardial perfusion imaging is imperfect in the absence of post-test referral bias

Diagnostics - Noninvasive scintigraphy is useful in the etiologic diagnosis of cardiac amyloidosis

Diagnostics - Studies advance knowledge in diagnostics research

Diagnostics - T1 determinations using a short acquisition period enable accurate cardiac measurements

Diagnostics - Time-frequency analysis of the second cardiac sound has diagnostic importance

Diet & Nutrition - Moderate alcohol intake may have vascular protective effects

Disease Associations - Analysis of tuberous sclerosis complex patients reveals novel mutations

Disease Associations - Cardiac troponin I predicts adverse events in stable coronary disease

Disease Associations - Coronary microembolization ultrasonically detected during percutaneous coronary interventions

Disease Associations - Elevated brain natriuretic peptide is diagnostic of chronic obstructive pulmonary disease

Disease Associations - Epithelioid hemangioendothelioma of the mitral valve may be diagnostic of valve tumors

Disease Associations - Interferon-gamma induces apoptosis in developing mast cells

Disease Associations - Intima-media thickness score from carotid and femoral arteries predicts extent of CAD

Disease Associations - Magnetic resonance measurements in thalassemia are consistent between medical centers

Disease Associations - Oral phosphate binders in the treatment of pseudoxanthoma elasticum

Disease Associations - Prior aspirin use is not a marker of increased mortality in elderly patients with acute MI

Disease Associations - Smoking and disease are predictive of thrombotic events in systemic lupus erythematosus

Drug Development - ACT 4 study initiated in acute treatment of atrial fibrillation

Drug Development - Synthetic glycosaminoglycan mimetic jumpstarts angiogenesis

Drug Development - U.S. FDA maintains clinical hold on IND application for RESUS phase II/III trial of Hemopure

Drug Research - Plasma homocysteine is not increased by the chronic administration of nandrolone

Echocardiography - Contrast agent dose, ultrasound exposure determine cardiomyocyte injury in rats

Echocardiography - New research in the area of echocardiography detailed

Enzymology - Ser/Thr kinase is expressed nonubiquitously in mice and men

Erectile Dysfunction - Tadalafil effective during thiazide diuretic hypertension therapy

Finance - Cardiovascular disease-focused company reports revenues of $3.5 million in Q1 2006

Fitness & Wellness - Effect of running exercise on endothelial progenitor cells studied in healthy subjects

Fitness & Wellness - Intensive training in healthy children does not negatively affect heart rate variability

Fitness & Wellness - More intense physical activity is beneficial for heart rate variability in middle-aged persons

Fitness & Wellness - Peripheral forearm vasodilatation in CAD is not improved by mild endurance exercise and pravastatin

Fitness & Wellness - Results show benefit of employer disease management programs

Fitness & Wellness - Use of intramyocellular lipids and glycogen during exercise is related to gender

Gene Delivery - VEGF gene transfer stimulates angiogenesis and muscle regeneration in ischemic muscles

Genetic Disorders - Nuchal translucency and nasal bone are useful markers for trisomy 21 screening

Genetics & Genomics - Genomics company forms pharmaceutical subsidiary focused on personalized medicine

HIV/AIDS Therapy - Abacavir/lamivudine/zidovudine improves HAART adherence in HIV-1-infected patients

HIV/AIDS-Related Atherosclerosis - HIV-1 Tat induces VCAM-1 expression in pulmonary artery endothelial cells

HIV/AIDS-Related Infection - Nocardiosis to be considered in HIV patients with low CD4 counts

Headache & Migraine - Clopidogrel reduces migraine with aura

Heart Disease - Cardiac magnetic resonance imaging is reproducible in chronic coronary artery disease

Heart Disease - Left atrial circumferential ablation decreases left atrial transport function

Heart Failure - High plasma adiponectin levels and BMI were mortality predictors despite CHF severity

Hematology - Novel quantitative whole blood test measures platelet function

Hemodialysis - Prosthetic graft implants improve vascular access in poor forearm vessels

High Cholesterol - Children's hospital to participate in study of single nucleotide polymorphisms

Hormone Replacement Therapy - Estrogen use associated with increased myocardial fatty acid utilization

Hormones - Aldosterone increases osteopontin gene expression in rat endothelial cells

Hormones - Cardiopulmonary bypass and surgical intervention affects natriuretic hormone system in children

Hormones - Thyroid hormone modulates renin and ANG II receptor expression in fetal sheep

Hypertension - Calcitonin gene-related peptide functions in hypertension

Hypertension - High blood pressure is inversely related to the presence and extent of coronary collaterals

Hypertension - Researchers provide details of new studies and findings in the area of hypertension

Hypoxia - Cerebral vascular processes are hindered by intermittent hypoxia

Imaging - Anatomic M-mode improves assessment of cardiac chamber size determination

Imaging - Collaboration and development agreement signed to develop X-ray angiography

Imaging - Doppler echocardiography is useful in evaluating aortic coarctation

Imaging - Findings advance knowledge in imaging research

Imaging - Manganese-enhanced MRI effectively depicts area at risk in canine model

Imaging - Radionuclide imaging dynamically tracks mesenchymal stem cells to myocardial infarction

Imaging - Real-time MRI used to guide pediatric endovascular procedures

Imaging - Three-dimensional outline of the heart and conduction pathway constructed

Imaging - U.S. FDA clearance of high-frequency intravascular imaging catheter announced

Infections - Toll-like receptor regulates cardiomyocyte hypertrophy triggered by Trypanosoma cruzi

Infective Endocarditis - Mitral valve repair is superior to valve replacement in active disease

Information Technology - ECG monitoring services provider achieves Mortara Certified Partner status

Intracranial Aneurysm Rupture - Endovascular coiling confers improved survival compared to neurosurgery

Ischemia - CH3-DTPA-GD (NMS60) is superior to GD-DTPA in evaluating acute myocardial ischemia

Ischemia - New data illuminates research in ischemia

Ischemia - Relaxin protects against isoproterenol-induced myocardial ischemia injury

Ischemia - Therapy potential of mitochondrial biogenesis regulatory program in ischemia discussed

Ischemia - Uncoupling proteins augment tolerance to cardiac ischemia

Ischemic Stroke - Data supports benefit of low energy ultrasound on thrombolytic drugs

Knee Replacement - Single-stage bilateral TKA may have fewer risks than reported

Left Ventricular Assist Device - Magnevad II 4th-gen axial flow LVAD effective in preliminary sheep trial

Legal Issues - Devices company reports patent lawsuits against AngioDynamics, Vascular Solutions

Lipid Research - Raloxifene positively affects lipid profile and body fat distribution

Lung Transplantation - Glutathione improves the function of porcine pulmonary grafts

Medical Devices - Bifurcation stenting presents an increased risk of stent thrombosis

Medical Devices - Frequency of late incomplete stent apposition after sirolimus-eluting stent implantation determined

Medical Devices - Medical device company establishes U.S. subsidiary in Delaware

Medical Devices - New Jersey insurer initiates payment for Microvolt T-Wave Alternans test

Medical Devices - Results find vascular brachytherapy effective treatment for in-stent restenosis

Medical Devices - Study shows arterial catheter securement device reduces restarts by nearly 49%

Men's Health - Men's health magazine reports on whether saunas are healthy or harmful

Mergers & Acquisitions - Acquisition of Swedish maker of heparin coating for medical devices announced

Migraine - Implant developer receives U.K. approval for migraine intervention study

Muscular Dystrophy - Early cardiac screening is necessary for muscular dystrophy patients

Myocardial Infarction - Coronary bypass before LVAD insertion for cardiogenic shock reduces survival

Myocardial Infarction - Endothelial nitric oxide synthase polymorphism is important during myocardial infarction

Myocardial Infarction - Hepatocyte growth factor generates therapeutic angiogenesis in ischemic canine hearts

Myocardial Injury - Menadione can restore calcium oscillations and cardiomyocyte contractility

Neurology - Endoderm-derived Fgf3 induces neurogenesis in epibranchial placodes

Neurology - New findings in the area of neurology detailed

Neuropeptides - Additional class of neuropeptide Y receptor sites exists in rat brain

Obesity Pathogenesis - Resistin and ghrelin increase adhesion molecule expression on vascular endothelial cells

Obesity Prevention - Children's media organization joins partnership to combat childhood obesity

Obesity Survival and Mortality - Morbid obesity is linked to cardiovascular survival in hemodialysis patients

Obesity Treatment - A new kind of appetite suppressant may mean hope for the obese

Obstetrics - Angiogenic balance may be essential for evading preeclampsia

Pacemakers - Biventricular pacing has proarrhythmic effect in some patients

Pacemakers - Temporary pacemaker use, steroid treatment predict permanent pacemaker effusions

Pediatric Cancer - Late effects in childhood cancer survivors analyzed to establish therapy starting point

Peptides - Intermedin may function as a cardiovascular active peptide

Peripheral Arterial Disease - Ankle-brachial index predicts asymptomatic peripheral arterial disease

Personnel - Medical device company names G. Ray Martin president and CEO

Personnel - Radiofrequency ablation company appoints Angelas as chief financial officer

Physiology - ATP-sensitive K channel Kir6.2 is regulated by ATP and PIP2

Physiology - C-terminal amino acids of SUR2A and SUR2B function in cardiovascular ATP-sensitive K+ channels

Physiology - Carbonyl reductase is involved in pig heart superoxide

Physiology - Reference value for asymmetric dimethylarginine determined

Physiology - Renal sympathetic nerve activity displays differential responses to arterial pressure changes

Physiology - Spironolactone corrects cardiorenal abnormalities associated with high sodium intake

Physiology - Synergistic interactions between Ca2+ entries occur in normal and failing rat heart

Physiology - Zolpidem exhibits sleep-related vagotonic effect

Preventive Medicine - Chronic diseases are leading cause of death, international health organization says

Proteomics - Findings in proteomics provide new insights

Quality Assurance - Ten hospitals selected to participate in program to improve cardiac care

Respiratory Medicine - Preterm neonatal endothelin-1 levels correlate with severity of respiratory distress syndrome

Smoking Cessation - Genetic testing may provide motivation in smoking cessation

Stem Cell Research - G-CSF enhances bone marrow stem cell mobilization during acute myocardial infarction

Stem Cell Transplantation - Embryonic stem cell immunogenicity increases upon differentiation after transplantation

Stents - Endovascular stenting is safe and effective for blunt renal artery injury

Stroke - Circulating beta amyloid protein is elevated in patients with acute ischemic stroke

Stroke - Oral atorvastatin has long-term protective effects in animal model

Stroke - Study establishes link between air pollution and ischemic strokes

Stroke - Three-year feasibility trials demonstrate durability of carotid artery stenting

Stroke Risk Factors - Serum homocysteine increases and folate decreases the risk of stroke

Surgical Techniques - New patch technique offers advantages in valve reconstruction and repair

Surgical Technology - Catheter effective for recanalization of femoropopliteal artery occlusions

Surgical Technology - Medical device company introduces low-profile surgical ablation system

Surgical Technology - Pivotal trial of percutaneous alternative to open-heart mitral valve surgery begins

Surgical Technology - Stent placement is an alternative to complex arterial bypass surgery or reconstruction

Surgical Technology - Study shows stent less prone to target vessel failure than brachytherapy

Surgical Technology - U.S. launch of technology for placing guidewires in coronary vessels announced

Thrombosis Therapy - Aprotinin needed to accurately monitor hemostatic system during desmoteplase treatment

Tissue Engineering - Extracellular matrix scaffold superior to synthetic material for cardiac repair

Tissue Engineering - Tissue regeneration observed in the repair of a right ventricle myocardial defect

Tobacco Use - Smokeless tobacco may contribute to coronary heart disease

Toxicity - High blood pressure is a symptom of paraquat-induced toxicity

Toxicology - Tefluthrin provokes cellular Ca2+ overload in ventricular myocytes

Transplant Medicine - Infectious tolerance in heart allografts can be adoptively transferred

Transplant Medicine - MEDOS/HIA VAD provides effective pretransplant mechanical circulatory support

Transplant Medicine - New data illuminates research in transplant medicine

Transplant Medicine - Stable mixed chimerism is required for the suppression of cellular rejection

Trypanosoma Cruzi - DHEA enhances reduces level of Trypanosoma cruzi parasites

Vasculogenic Erectile Dysfunction - Novel rat model of VED with generalized atherosclerosis validated

Vasodilation - Circulating elastin peptide levels decrease in humans with sepsis

Weight Loss - Study finds exercise plus weight loss yields most cardiovascular benefit

Wound Repair - Pharmacological preconditioning extends the survival of ischemic skin flaps

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