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Blood Clotting

Coagulation system is activated in Duchenne muscular dystrophy patients with cardiac dysfunction

Published in Cardiovascular Week, November 14th, 2005

According to a study from Japan, the coagulation system is activated in Duchenne muscular dystrophy (DMD) patients with cardiac dysfunction.

"We investigated basic abnormalities of coagulation and fibrinolysis in DMD patients with cardiac dysfunction," wrote T. Saito and colleagues, National Hospital Organization Toneyama National Hospital.

"Forty seven patients with DMD, aged 13-37 years old, were enrolled. Based on left ventricular ejection fraction (LVEF) results determined by echocardiography, patients were divided into 3 groups: LVEF less than 30% (markedly depressed group), LVEF between 30 and 50% (slightly depressed), and LVEF greater than 50%...

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