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Cardiovascular Week

Susan Hasty, Publisher

Table of Contents . . . December 19th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cardiovascular Week | Other Publications

Cardiovascular Disease - Dietary magnesium intake was not shown to reduce risk of cardiovascular disease

Cardiovascular Risk Factors - Weight-loss surgery's effect on major cardiovascular risk factors is assessed

Early Renal Disease - Systemic and vascular inflammation is linked to CVD risk factors and renal function

Heart Disease - Self-rated health is related to inflammation in women with coronary heart disease

Medical Devices - Pericardium-coated prosthetic annuloplasty ring lowers hemolysis risk

Anaphylaxis - Researchers warn that anaphylaxis requires prompt and appropriate treatment

Angiography - Breast radiation exposure during pulmonary CT scan exceeds dose for mammography

Angiology - Enrollment complete in international drug-eluting stent clinical trial

Angiology - Findings in angiology provide new insights

Angiology - Receptor gene polymorphism may contribute to acute myocardial infarction

Angiology - Research in angiology provides new insights

Angiology - Review discusses antiatherosclerotic treatments for PAD patients

Angiology - Review discusses venous thromboembolism risk and thromboprophylaxis in subjects with comorbidities

Apoptosis - Researchers describe findings in apoptosis studies

Arteriogenesis - Vector encoding sphingosine kinase boosts revascularization in rabbit ischemic limbs

Atherosclerosis - Cell function changes can contribute progression of atherosclerosis

Atherosclerosis - Researchers' data advance atherosclerosis research

Atherosclerosis - Expression of scavenger receptor CD may accelerate atherosclerosis progress in diabetics

Atherosclerosis - HERP1 inhibits myocardin-induced vascular smooth muscle cell differentiation

Atherosclerosis - Insulin regulates p70S6k and 4E-BP1 in HUVEC/HVSMC cells and promotes atherosclerosis

Atherosclerosis - MMP-9 microsatellite polymorphism is linked to carotid atherosclerotic plaques

Atherosclerosis - Research add new data to atherosclerosis body of knowledge

Cardiology - New findings in the area of cardiology described

Atrial Myxoma - Left atrial myxoma diagnosed by cardiac magnetic resonance imaging

Awards - Biopharmaceutical company wins 2005 Prix Galien Award for excellence in research

Biomedical Engineering - Java software calculates mean breath-by-breath variability in gas exchange parameters

Business & Finance - Forbes Medi-Tech announces third-quarter 2005 financial results; revenues CDN$6.02M, up 12%

Business & Finance - Maker of gene-transfer therapy products reports third-quarter revenues of $21,000

Cancer Screening - Abdominal CT plus mammogram improves cancer detection in IVTE patients

Cardiology - New findings in the area of cardiology detailed

Cardiac Arrhythmias - Quantitative analysis allows for more specific classification of cardiac arrhythmias

Cardiology - BI-204 significantly impedes plaque formation, reduces existing plaque size

Cardiology - Cord blood stem cells and gene therapy combine to spur angiogenesis after myocardial infarction

Cardiology - Diabetes increases risk of in-hospital mortality in women with acute coronary syndrome

Cardiology - Findings in cardiology provide new insights

Cardiology - Low bone mineral density is a predictor of coronary artery disease in women

Cardiology - Recent findings in cardiology provide new insights

Cardiology - Maker of hand-carried ultrasound expands capabilities for pediatric cardiology

Cardiology - Mayo Clinic researchers redefine how the heart functions

Cardiology - Reports advance knowledge in cardiology research

Cardiology - Study shows addition of Integrelin to oral platelet therapy more effective at reducing inflammation

Cardiology - Study shows that volunteer-operated defibrillators may be life savers

Cardiology - Reports describe recent advances in cardiology research

Cardiology - Women's toughness about their heart disease may contribute to less-agressive care

Cardiomyopathy - Recent findings illuminate research in cardiomyopathy

Cardiovascular Disease - 50,000 patients enrolled in Internet-based implantable cardiac device management system

Cardiovascular Disease - Periodonitis patient's plasma lipoprotein profile may be link with cardiovascular disease

Cardiovascular Disease - Reports add new data to cardiovascular disease research

Cardiovascular Disease - Study of three diets published, role of plant proteins discussed

Cardiology - Researchers' data advance cardiology research

Cardiovascular Research - Aortic calcification raises incidence of cardiovascular events

Cardiovascular Research - Aspirin resistance associated with impaired coronary flow reserve in elective PCI patients

Cardiovascular Research - Cardiac arrhythmia common in older patients

Cardiovascular Research - Data demonstrate Lp-PLA2 is better predictor of cardiovascular disease in older women

Cardiovascular Research - Fat tissue surrounding the thoracic arteries may be beneficial for bypass surgery patients

Cardiovascular Research - QRS duration is linked to increased risk of death in patients with coronary artery disease

Cardiology - Studies add new findings to cardiology body of knowledge

Cardiovascular Research - Researchers describe findings in cardiovascular studies

Cardiovascular Research - Studies show blood pressure measured at heart more predictive of outcomes than traditional method

Cerebral Aneurysm - Presidio Microcoil product line launched for the treatment of large cerebral aneurysms

Cholesterol - Study finds individuals who switch statins are 18.9% less compliant and 44.2% less persistent

Clinical Trials - Trial of Celacade technology in advanced chronic heart failure reaches key objective

Clinical Trials - Type 2 diabetes trial shows fenofibrate can reduce cardiovascular disease

Heart Failure - Researchers' data advance heart failure research

Collaborations - Pharma company and Incyte collaborate to develop and manufacture oral CCR2 antagonists

Complementary & Alternative Medicine - Study: Chromium picolinate may provide cardiovascular benefits in prediabetes

Coronary Artery Bypass - Data review reveals emergency bypass surgery on angioplasty patients has dropped 90%

Coronary Artery Bypass - Drug-eluting stents help keep heart bypass vein grafts open

Coronary Artery Bypass - Researchers' data advance coronary artery bypass research

Coronary Artery Disease - Esomeprazole magnesium shown to reduce non-cardiac chest pain and physician visits

Heart Failure - Researchers' work adds to heart failure body of knowledge

Coronary Artery Disease - Patient enrollment commences in clinical outcomes trial conducted for Vytorin

Coronary Artery Disease - Risks accompany attempts to jumpstart angiogenesis with G-CSF-induced stem cell mobilization

Coronary Bifurcations - Excellent results seen in study of coronary bifurcations treated with the CYPHER stent

Deep Vein Thrombosis - Thrombin profile based on blood composition may be predictive marker for thrombosis

Developmental Biology - Apolipoprotein E gene deficiency is linked to cochlear alterations

Diabetes Comorbidity - Review proposes to treat depression in diabetics with omega-3 polyunsaturated fatty acids

Imaging - Findings describe new data in imaging research

Diabetes Complications - Diabetics treated for coronary intervention with SESs have higher risk than nondiabetics

Diabetes Complications - Lack of aspirin protection in diabetics may be related to aspects of platelet function

Diabetes Complications - Patients with diabetes have a higher risk of mortality after LVAD implantation

Diabetes Complications - Postoperative blood glucose levels were linked to surgical wound infections

Diabetes Complications - Urinary albumin levels indicate risk of ischemic cardiac mortality in type 2 diabetes

Diabetes Control - Primary care diabetic and GP clinics do not adequately treat hypertension and diabetes

Imaging - Recent findings in imaging provide new insights

Diabetes Control - Review provides insights into cardiometabolic prevention and management of DM

Diabetes Research - FFT analysis should be chosen over AR for study of heart rate variability in diabetics

Diabetes Therapy - Tocotrienols prevents and treats hyperlipidemia and atherogenesis in type 2 diabetics

Diagnostics - New findings in the area of diagnostics detailed

Diet & Nutrition - Diet-genotype interaction may be therapeutic in atherogenic dyslipidemia

Diet & Nutrition - Mouse model indicates fermented-brown rice may have potent cholesterol-lowering benefit

Imaging - Researchers' findings advance imaging research

Diet & Nutrition - Recent studies add new data to diet & nutrition research

Diet & Nutrition - Review shows that providing diet advice leads to a modest drop in cardiovascular risk factors

Diet & Nutrition - Vitamin E prevents development of atherosclerosis in diabetic BALB/c mouse model

Disease Associations - Postprandial lipid metabolism is a link between adiponectin and liver disease

Disease Associations - Reduced mitochondrial oxidative capacity impair myocardial energetics in obese mice

Drug Development - Pexelizumab does not meet primary endpoint in phase III trial

Drug Development - Positive results reported from long-term animal study of stent coating technology

Drug Safety - Heparin antibodies may pose a risk for heart surgery patients

Finance - Developer of peptide-based therapies announces third-quarter net loss of $1,618,521

Finance - Medical device company reports revenues of $2.765 billion

Finance - Medical device company reports sales of $15.5 million for first quarter

Finance - Medical devices company reports Q3 2005 net revenues of $12.1 million

Finance - PAD-focused biotechnology company reports Q1 2006 net loss of $3.6 million

Finance - Robotic technology company secures $30 million in series C financing led by Vanguard Ventures

Fitness & Wellness - Regular aerobic exercise improves endothelial t-PA release in overweight and obese

Fitness & Wellness - Weight loss is linked to lower blood pressure and improved insulin resistance in obese

Genetics & Genomics - Genetic mechanism identified that causes new arteries to grow when existing arteries are blocked

Genetics & Genomics - MTHFR 677TT and 677CT/1298AC genotypes may predispose to nephrosclerosis and CRF

Genetics & Genomics - Scientists identify gene for disease that impairs vitamin B12 management

HIV/AIDS Drug Interactions - Few data are available regarding PI interactions with other complex treatment regimens

HIV/AIDS HAART - Atazanavir-treated patients have better lipid profile than lopinovir/ritonavir-treated patients

HIV/AIDS-Associated Pulmonary Hypertension - Secreted HIV gp120 proteins induce lung endothelial cell injury

Heart Disease - Inflammatory markers based on plasma IL-6 and fibrinogen levels can predict IHD risk

Heart Disease - Trials are needed to examine effect of lipid-lowering therapy and CHD risk in women

Heart Failure - Natrecor-treated heart patients less likely to die from serum creatinine increases

Heart Failure - Reports describe recent advances in heart failure research

Heart Failure - Trial set to test a human implant of the HeartPOD

Hematology - Erythropoietin multiplies the proliferative and adhesive properties of endothelial progenitor cells

Hypertension - Glucose intolerance tests are important for proper care of hypertensive patients

Hypertension - Recent studies add new data to hypertension research

Imaging - Data advance knowledge in imaging research

Imaging - Imaging systems company gives $100,000 in founding support to cardiovascular CT society

Imaging - LightSpeed VCT to be used in clinical research of pediatric heart defects

Ischemia - Researchers detail new studies and findings in the area of ischemia

Lipid Research - U.S. FDA approves SNDA for new dosing regimen, label change of fenofibrate therapy

Market Analysis - Global revenues from hypertension drugs set to rise

Medical Devices - 501(k) application submitted to U.S. FDA for Primo blood pressure monitoring system

Medical Devices - Contrast delivery system released for cardiovascular angiographic procedures

Medical Devices - Hemaport needle-free arteriovenous vascular access device effective in initial clinical use

Medical Devices - Talent Thoracic stent graft system premarket approval module submitted to U.S. FDA

Medical Devices - Whole blood glucose biosensor operates acceptably due to low sensitivity to hematocrit

Medicare - Medicare proposes a new coverage policy for bariatric surgery procedures

Mergers & Acquisitions - Drug-delivery company purchases assets of Phytogen Life Sciences

Myocardial Infarction - Mesothelial cell transplants generate vessel growth in injured hearts

Neurogenesis - TNF-alpha antibody infusion impairs survival of stroke-generated neuroblasts

Neuropeptides - Researchers report details of new studies and findings in the area of neuropeptides

Obesity Complications - Overweight and underweight patients are at higher risk for inflammation and atherosclerosis

Obesity Complications - Tinzaparin reduced vWF levels in obese subjects

Obesity Complications - Waist-to-hip ratio is more effective than BMI for determining myocardial infarction risk

Obesity Therapy - Overproducing leptin receptors in fat cells may play role in blocking weight gain

Obesity Therapy - Rimonabant hydrochloride reviewed as treatment for obese with cardiovascular risk factors

Osteoporosis - Cardiovascular event risk is proportional to osteoporosis severity at diagnosis

Personnel - Key positions added to management team at cardiology-focused company

Pharmaceutical Research - Study shows additional analysis of medical studies could prevent medical safety issues

Physiology - Findings describe new data in physiology research

Pulmonary Arterial Hypertension - Revatio effective, well tolerated in treatment of pulmonary arterial hypertension

Statins - Persistence with statin therapy is low among middle-aged free of CV disease

Statins - Researchers publish new studies and findings in the area of statins

Stem Cell Research - Adipose stem cells improve cardiac function and blood flow in preclinical heart attack study

Stem Cell Research - Endothelial progenitor cells respond to PAR-1 with concentration-dependent angiogenesis

Stem Cell Research - Fetal stem cells may accelerate tissue repair

Stem Cell Research - MSCs can be mobilized and differentiate into cardiomyocytes after myocardial infarction

Stem Cell Research - Retinoid X receptor agonist enhances differentiation of ESC-derived cardiomyocytes

Stem Cell Therapy - Iron particles and MRI used to track stem cell therapy for heart attack in animal model

Stroke - Adosterone is a promising target for stroke treatment, according to a new study

Stroke - Clinical trials are reviewed for stroke risk factors, complications, and treatments

Stroke - Gln192Arg polymorphism in paraoxonase 1 gene is linked to increased stroke risk

Stroke - Many adults with multiple risk factors do not recognize their stroke risk

Stroke - PDE4D gene can be significantly associated with small vessel infarction

Stroke - Relative cerebral blood flow measures are poor predictors of cerebral infarct size

Stroke - Tirofiban and urokinase with mechanical thrombolysis can resolve cerebral artery occlusion

Surgical Technology - Endovascular surgical repair feasible in geriatric patients

Surgical Technology - Endovascular treatment with nitinol vascular occlusion plug shows promise

Surgical Technology - Mitral valve rerepair feasible and effective

Surgical Technology - Protamine treatment doesn't increase granulocyte elastase levels

Surgical Technology - Recent studies add new data to surgical technology research

Surgical Technology - Spinal cord ischemia seen in >10% of patients after emergency endovascular treatment

Thrombosis - No significant changes were noted in inflammatory markers with transdermal HRT

Thrombosis - Researchers describe findings in thrombosis studies

Tobacco Use - COPD prevalence in China increases with number of cigarettes smoked

Transplant Medicine - Free fatty acids are linked to obesity, insulin resistance, and atherosclerosis in RTRs

Transplant Medicine - Researchers' findings advance transplant medicine research

Transplantation Medicine - Actin cytoskeleton regulator depletion suppresses cardiac allograft rejection

Transplantation Medicine - Transplant patients with CHF and LVEF are at high risk for cerebrovascular accidents

Type 2 Diabetes - NCX 4016 shows insulin sensitivity improvement and systemic hemodynamics

Type 2 Diabetes - Simvastatin reduces prothrombinase activity and PAI-1 levels in diabetes mellitus patients

Type 2 Diabetes - Smoking was linked to higher risk of diabetes in patients with impaired functional capacity

Vascular Disease - Pioglitazone shown to reduce further heart attack risk by 28% in type 2 diabetics

Venous Disease - Women with venous problems are often employed in work that worsens venous disease

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