Sleep Apnea

Sleep apnea may accelerate progression of heart failure

Published in Cardiovascular Week, January 30th, 2006

Sleep apnea represents an additional stimulus to central sympathetic outflow that may accelerate the progression of heart failure (HF); its attenuation by treatment of sleep apnea represents a novel nonpharmacological opportunity.

According to recent research appearing in the journal Hypertension, "Sympathetic activation and sleep apnea are present in most patients with symptomatic systolic heart failure (HF). Acutely, obstructive and central apneas increase muscle sympathetic activity (MSNA) during sleep by eliciting recurrent hypoxia, hypercapnia, and arousal."

"In obstructive sleep apnea patients with normal systolic function, this...

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Source: Cardiovascular Week (2006-01-30)

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