Published in Cardiovascular Week, January 30th, 2006
Study 1: Muraglitazar increases risk of death and major adverse cardiovascular events in patients with type 2 diabetes.
According to a report from the United States, "Peroxisome proliferator-activated receptors (PPARs) are nuclear transcription factors that modulate gene expression. Therapeutic agents targeting two distinct families of PPARs (alpha and gamma) have been introduced in the United States. The first dual-PPAR agonist, muraglitazar, was reviewed by a U.S. Food and Drug Administration (FDA) advisory committee on September 9, 2005, resulting in a vote of 8:1...
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Source: Cardiovascular Week (2006-01-30)
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