Cardiovascular Week
Susan Hasty, Publisher
Table of Contents . . . March 13th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Cardiovascular Week | Other Publications
Cardiovascular Disease - Chronic obstructive pulmonary disease inflammation may be signaled by C-reactive protein
Cardiovascular Research - Exercise-induced myocardial flow reserve was decreased by caffeine
Pediatric Cardiology - Cyanotic congenital heart disease is detectable with pulse oximetry in newborns
Statins - Coronary atherosclerosis progression was unattenuated with intensive atorvastatin treatment
Stem Cell Mobilization - Chronic heart failure may be attenuated by blood stem cell mobilization
Alzheimer Disease - Alzheimer disease risk reduction with statin therapy may be basis for primary prevention trials
Anesthesia - T-Line Tensymeter provides noninvasive surgical blood pressure monitoring
Angina - Successful clinical application of PHOENIX TMR plus stem-cell delivery system announced
Angiology - Aneurysm endovascular polyester vein graft treatment superior to ePTFE grafts
Angiology - Arterial stiffness is augmented in menopause
Angiology - Cardiovascular disease-associated superoxide stress was modulated by vascular Menkes ATPase
Angiology - Dipyridamole is reconsidered as an underestimated vascular protective drug
Angiology - Hyperglycemia after glucose load is preclinical atherosclerosis predictor in nondiabetics
Angiology - Hyperhomocysteinemia inhibits postinjury re-endothelialization in mice
Angiology - In acute coronary syndrome, plaque temperature is elevated in nonculprit atheromatous lesions
Angiology - New research in the area of angiology detailed
Angiology - Pro-inflammatory activation of endothelial cells by thrombin is inhibited by aprotinin
Angiology - Recent findings in angiology described
Angiology - Researchers publish new studies and findings in the area of angiology
Apoptosis - Recent findings illuminate research in apoptosis
Arterial Occlusive Disease - Postangioplasty femoropopliteal stenosis prevented by endovascular gamma irradiation
Atherosclerosis - Atherosclerosis accelerated by Porphyromonas gingivalis was focus of review
Atherosclerosis - Atherosclerosis and progeria linked to mutant protein
Atherosclerosis - Atherosclerosis instigated by adipokine gene expression following oxidative stress
Atherosclerosis - Coronary artery disease risk was underestimated by Framingham risk function
Atherosclerosis - Diabetics with delayed triglyceride metabolism appear to have higher atherosclerosis risk
Atherosclerosis - New findings in atherosclerosis described
Atherosclerosis - New findings in the area of atherosclerosis described
Atherosclerosis - Restenosis in atherosclerosis coronary stent and angioplasty differ in inflammatory cell behavior
Atrial Fibrillation - New research in the area of atrial fibrillation detailed
Biomedical Engineering - Coronary artery stents can be improved by increasing ductility via optimization of microstructure
Biomedical Engineering - Pediatric cardiovascular disease circulatory support technology is under development
Breast Cancer Therapy - sBLA submitted for adjuvant Herceptin in early-stage HER2-positive breast cancer
Business & Finance - Alexion Pharmaceuticals reports increased R&D expenses
Business & Finance - Cardica files post-effective amendment
Business & Finance - Cardium Therapeutics' resale registration statement is declared effective
Business & Finance - Escalon Medical Corp. reports net revenue of $7,310,000
Business & Finance - Stem-cell company Cytori Therapeutics joins Nasdaq National Market
Business & Finance - Vascular drug-delivery company receives notice of remediation of Nasdaq noncompliance
Cardiac Valvular Disease - Hydroxytryptamine transporter gene deficiency preludes cardiac fibrosis and valvulopathy
Cardiology - Acute coronary syndromes management in prehospital period reduced mortality, morbidity
Cardiology - Aortic valve replacement with severe prosthesis mismatch has lower long-term survival
Cardiology - Aprotinin use in cardiac surgery is linked to end-organ damage
Cardiology - Arrhythmia, sudden death after conduit repair may be reduced by earlier primary operation
Cardiology - Arrhythmogenic defects reveal mechanism of Ca2+ release channel dysfunction
Cardiology - Atrial fibrillation after ablation may be associated with endurance exercise history
Cardiology - Atrial fibrillation management issues and controversies are reviewed
Cardiology - Cardiac arrest neurologic outcome improved by automated chest compression device
Cardiology - Cardiac conduction variability is linked to sodium channel promoter haplotype in Asian subjects
Cardiology - Cardiac fatty acid metabolism is preserved in the compensated hypertrophic rat heart
Cardiology - Combined supine-prone quantification show improved obstructive CAD recognition
Cardiology - Early intervention with cardiac defibrillators saves lives and money
Cardiology - Findings describe new data in cardiology research
Cardiology - Implantable cardioverter defibrillator survival rates are comparable in elderly patients
Cardiology - Laminin gene deficiency produces heart disease and capillary defects in mice
Cardiology - Long QT syndrome studies can assist in analyzing other complex gene-environment interactions
Cardiology - MDS Nordion, Molecular Insight contract for imaging pharmaceuticals for cardiac ischemia
Cardiology - MRI superior to conductance microcatheter for LV function assessment
Cardiology - Natural HDL booster increases good HDL cholesterol, reduces cardiovascular risk
Cardiology - New data illuminates research in cardiology
Cardiology - New findings in cardiology described
Cardiology - New findings in the area of cardiology described
Cardiology - New research in the area of cardiology detailed
Cardiology - Percutaneous coronary intervention may be linked to vascular complications in women
Cardiology - Recent findings in cardiology provide new insights
Cardiology - Researchers detail new studies and findings in the area of cardiology
Cardiology - Researchers publish new studies and findings in the area of cardiology
Cardiology - Researchers' findings advance cardiology research
Cardiology - Statins to remain top coronary heart disease treatment though market to decline, study shows
Cardiomyocytes - Atrial fibrosis was ameliorated by cardiomyocyte cell cycle activation
Cardiomyocytes - Recent studies add new data to cardiomyocytes research
Cardiovascular Disease - Acarbose reduces cardiovascular event risk in patients with impaired glucose metabolism
Cardiovascular Disease - Angiotensin II antagonists offer therapeutic benefits to cardiovascular disease patients
Cardiovascular Disease - Antihypertensive regimens may have to differ between men and women
Cardiovascular Disease - Aortic counterpulsation hemodynamics and indications for use are reviewed
Cardiovascular Disease - Aortic valve calcification severity, location are associated with increased pressure gradient
Cardiovascular Disease - Cardiac nonamyloidotic immunoglobulin deposition disease may be signaled by cell dyscrasias
Cardiovascular Disease - Cardiovascular disease prevention guidelines of future will consider broader disease context
Cardiovascular Disease - Coronary artery disease "polypill" cost may be prohibitive unless carefully targeted
Cardiovascular Disease - Estrogen therapy does not protect postmenopausal women from heart disease
Cardiovascular Disease - Heart disease in women focus of widely supported federal legislation
Cardiovascular Disease - In cardiac hypertrophy, guanosine triphosphatase activation occurs downstream of calcineurin
Cardiovascular Disease - In non-ST-segment elevation acute coronary syndromes, elevated troponin signals acute risk
Cardiovascular Disease - Obese middle-aged have higher risk of mortality from CHD and diabetes
Cardiovascular Disease - Renal transplant recipients with altered glycemia show higher BMI and Hb1Ac
Cardiovascular Disease - Takayasu arteritis has excellent long-term survival regardless of perioperative disease activity
Cardiovascular Research - Researchers' work adds to cardiovascular body of knowledge
Cardiovascular Research - Stent system studies show positive results in small vessels
Cardiovascular Research - Studies add new findings to cardiovascular body of knowledge
Cardiovascular Risk Factors - Cardiovascular risk factors are undertreated and undercontrolled in most of the world
Cardiovascular Risk Factors - Cardiovascular risk management and rationale for combination therapy are presented
Cell Biology - Pericytes influence endothelial cell growth
Chest Pain - Non-cardiac chest pain may be caused by peripheral or central sensitization
Clinical Trials - Dosing of anti-inflammatory drug for peripheral arterial disease in 2b trial on schedule
Clinical Trials - Significant trial results on antisense drug to reduce cholesterol in humans reported
Collaborations - Mended Hearts, American Medical ID partner to offer medical IDs to heart patients
Complementary & Alternative Medicine - Cardiovascular benefits of ginseng are not yet substantiated
Complementary & Alternative Medicine - Systolic BP, diastolic BP, and HR were higher following single bitter orange dose
Congestive Heart Failure - NQCI reports that removing salt and fluids is effective in patients with congestive heart failure
Contraception - Ortho Evra studies provide important new clinical and safety information
Coronary Artery Bypass - Coexistent carotid, coronary atherosclerosis were treated with carotid stenting, staged CABG
Defibrillators - U.S. FDA grants 510(k) clearance for new "crash cart" defibrillator
Diabetes Complications - Adenosine receptor expression is altered in the hearts of diabetic rats
Diabetes Complications - CAD screening guidelines in asymptomatic type 2 diabetes mellitus evaluated
Diabetes Complications - Cardiac function and ischemic tolerance sensitivity increase after metabolic control loss
Diabetes Complications - Elevated HbA1c levels linked to improved survival in diabetes and advanced systolic HF
Diabetes Complications - Insulin resistance and atherosclerosis risk increase with adiponectin levels
Diabetes Complications - Pioglitozone reduces leptin levels and improves endothelial function in type 2 diabetics
Diabetes Complications - Postprandial hyperglycemia may increase atherosclerotic cardiovascular disease risk
Diabetes Pathogenesis - Studies add new findings to diabetes pathogenesis body of knowledge
Diabetes Therapy - Diabetics experience less CV events after low-dose statin therapy with atorvastatin
Diabetes Therapy - Insulin analog reversed myocardial perfusion deviations by improving glucose control
Diabetes Therapy - Proinsulin levels are elevated in type 2 diabetics treated with sulfonylurea
Diabetes Therapy - Recent studies add new data to diabetes therapy research
Diabetes Therapy - Reports advance knowledge in diabetes therapy research
Diagnostics - Cardiovascular data imaging gains improved technique for center lumen line definition
Diagnostics - Clinical heart examination during imaging can provide additive information
Diagnostics - Research in diagnostics provides new insights
Diagnostics - Researchers' data advance diagnostics research
Diet & Nutrition - Atherosclerosis development was retarded by fish oil supplementation in murine models
Diet & Nutrition - Heart disease risk lowered by adding grapefruit to the daily diet
Drug Development - Cancer, cardiovascular disease are potential targets of 2-Cys peroxiredoxins
Drug Development - hERG liability can be identified using electrophysiology techniques
Electrocardiography - Brugada-type EKG is uncommon, not tied to higher mortality risk among Japanese-American men
Emergency Medicine - CPR for cardiac arrest improved by tracheal intubation
Finance - CardioDynamics reports 21% decrease in sales
Finance - CardioTech International reports 3.9% increase in revenue
Finance - Forest Laboratories revises research and development spending projection
Finance - Samaritan Pharmaceuticals to devote much of $40 million dollar financing to R&D
Finance - Sangamo reports consolidated net loss of $2.7 million for 2005 fourth quarter
Finance - Vascular drug-delivery company reports Q4 net loss of $20.1 million
Gastroenterology - Colonic ischemia, serious constipation, and irritable bowel syndrome studied using insurance claims
Genetics & Genomics - CAD severity risk is increased by eNOS polymorphism combined with hyperhomocysteinemia
Genetics & Genomics - Chromosome rearrangements not as random as believed
Genetics & Genomics - Metabolic syndrome prevalence in aboriginal Canadians finds three candidate genes
Genetics & Genomics - Oxidative stress-related damage could be target for carnitine antioxidant effect
HIV/AIDS Prognosis - C-reactive protein is a marker for human HIV-1 disease progression
HIV/AIDS Therapy - Coronary heart disease risk may increase in HIV-infected patients after PI-based treatment
Health Economics - Cardiovascular disease presents significant economic burden on E.U.'s 25 countries
Health Promotion - African American women targeted by campaign to improve health habits
Healthcare Access - Increases in cardiac services use fail to narrow treatment gaps in U.S.
Healthcare Costs - Medicare sustainability is challenged by cardiac testing proliferation in Canada
Heart Disease - Atherosclerosis risk in asymptomatic women is underestimated by Framingham equation
Heart Failure - Carvedilol blocks beta2 - more than beta1 -adrenoceptors in human hearts
Heart Failure - Dyssynchronous failing heart shows evidence of structural remodeling
Heart Failure - Heart failure-related healthcare costs can be curbed with neurohormonal blockade use
Heart Failure - In chronic heart failure patients, beta-blockers can increase total body fat
Heart Failure - In chronic heart failure, escape from ACE inhibition may be caused by feedback mechanism
Heart Failure - In heart failure, carvedilol exerts more potent antiadrenergic effect than metoprolol
Heart Failure - New heart failure guidelines emphasize self care
Heart Failure - Nonischemic heart failure, but not coronary artery disease, was predicted by renal function
Heart Failure - One third of hospitalized congestive heart failure patients were thiamin-deficient
Heart Failure - Research add new data to heart failure body of knowledge
Hepatitis B Virus - Hepatitis B core antibodies are frequently detected in heart transplant recipients
Home Healthcare - Study shows patient self-monitoring market is positioned for growth
Hypercholesterolemia - Pravastatin reduced P-selectin expression on platelets in hypercholesterolemic women
Hyperglycemia & Hepatitis C - Hyperglycemia in those with hepatitis C displays an unconventional diabetic phenotype
Hypertension - Hypertension and microalbuminuria are outdated terms in need of revision
Hypertension - Blood pressure is increased in absence of D4 dopamine receptor
Hypertension - Cardiovascular disease risk is predicted by hyperuricemia combined with LV hypertrophy
Hypertension - Hypertension can be predicted by metabolic variations, lipid profiles, and blood pressure
Hypertension - Multiple antihypertensive use is increasing among adults with hypertension
Hypertension - New data illuminates research in hypertension
Hypertension - New series of renin inhibitors for hypertension reaches late-stage preclinical profiling
Hypertension - Pulmonary hypertension, vascular remodeling reversed by soluble guanylate cyclase activation
Hypertension - Recent findings illuminate research in hypertension
Hypoxia - Cerebral hypoxic preconditioning could result from phosphorylation of element binding protein
Hypoxia - Desflurane-treated brain tissue recovers significantly better than untreated hypoxic tissue
Imaging - Acute coronary syndrome, stenosis are identifiable with additive coronary flow reserve data
Imaging - Acute, healed myocardial infarction extent was quantified by contrast-enhanced MDCT
Imaging - Congenital heart disease may be marked by fetal heart block, increased nuchal translucency
Imaging - Congenital heart disease pediatric patient scanning protocol for 3-D CT angiography is suggested
Imaging - Coronary artery calcifications rule-out using MDCT requires different intervals
Imaging - Coronary artery calcium volume may best be measured by thin-slice spiral CT scanning
Imaging - Coronary artery disease assessment and nuclear cardiology, cardiac CT, and MRI roles are examined
Imaging - Coronary artery disease is accurately detected by 16-MDCT angiography
Imaging - Dental patients requiring antibiotic prophylaxis must be fully evaluated
Imaging - Findings describe new data in imaging research
Imaging - MRI skeletal muscle perfusion testing with noninvasive single-voxel FAIR promising
Imaging - Research add new data to imaging body of knowledge
Imaging - Systemic atherosclerotic disease can be assessed quickly with whole-body imaging
Inflammation - Systemic inflammation and adiposity are strongly associated in women
Information Technology - Cisco, Philips, and Emergin to collaboratively develop patient monitoring solution
Information Technology - Deep Freeze protects the heart of Volcano Corp.'s medical devices
Ischemia - Critical limb ischemia may be attenuated with Rheopheresis
Ischemia - Modulation of PGE2 receptors may protect against neuronal injury induced by focal ischemia
Ischemia - Research in ischemia provides new insights
Ischemic Stroke - Antiapoptotic therapies may be appropriate for use against delayed neuronal cell death
Ischemic Stroke - Ischemic stroke study clinical data points to promising drug delivery treatments
Kidney Function & Arterial Stiffness - Kidney function, arterial stiffness, and genetic factor interactions warrant further study
Lipid Research - Apolipoprotein A-V may be a modulator of plasma triglyceride levels in Turks
Lipid Research - Lipid management requires greater awareness, improved intervention
Marketing - GE launches "Healthcare Re-Imagined'' marketing campaign
Medical Devices - Congestive heart failure treated with DexAide RVAD in animal tests
Medical Devices - French government approves reimbursement for coronary stent system
Medical Devices - Taxus stent is more cost effective than bare metal stents for Swedish patients
Menopause - Postprandial lipemia's main determinant is fasting triglyceride concentration
Myocardial Infarction - After MI, endothelial function relation between arteries was shown by flow-mediated dilatation
Myocardial Infarction - Erectile dysfunction drug protects against cardiac tissue damage after heart attack
Myocardial Infarction - In acute myocardial infarction, door-to-balloon time impacts mortality in high-risk patients
Myocardial Infarction - Myocardial infarct size is limited by chronic erythropoietin treatment
Myocardial Infarction - Myocardial infarction susceptibility may be influenced by human OX40 gene variants
Myocardial Infarction & Dementia - Myocardial infarction and dementia association remains uncertain
Natural Products - Salacia oblonga root improves cardiac lipid metabolism in Zucker diabetic fatty rats
Neuroscience - Amiloride analogues are neuroprotective when commenced before hypoxia/ischemia in a mouse model
Neurosurgery - Adding furosemide to hypertonic saline decreases brain water content without increasing osmolality
Obesity - Results of RIO-North America obesity study with rimonabant published in JAMA
Obesity Complications - Obesity is linked to higher death rates from cardiovascular diseases, diabetes, and accidents
Obesity Complications - tHcy levels are not link to carotid IMT in obese during the nonatherogenic stage
Obesity Epidemiology - Obesity and weight gain is common following renal transplantation
Obesity Pathogenesis - Adipose differentiation-related protein is mediated through ubiquitin/proteasome pathway
Obesity Pathogenesis - Cardiac myocyte apoptosis is linked to higher DNA damage and mortality in obesity model
Obesity Pathogenesis - MC3/4-R metabolic and cardiovascular actions are preserved in diet-induced obesity
Obesity Therapy - Rimonabant shows modest benefit in reducing weight, improving HDL levels
Oxidative Stress - DNA damage is decreased by carotenoid supplementation
Patents - Targeted Genetics reports issuance of added patent for AAV vector manufacturing processes
Pediatric Cardiology - Findings in pediatric cardiology provide new insights
Pediatric Cardiology - Implantable cardioverter defibrillator use in children is feasible with psychological monitoring
Pediatric Cardiology - In neonates with transposed great arteries, balloon atrial septostomy is a risk factor for preop stroke
Periodontitis - Periodontitis inflammation and bone loss were reduced by Resolvin E1
Peripheral Vascular Disease - Angiogenesis signals accrue in human critical limb ischemia
Personnel - Dr. Barbara McNeil elected to board of cardiovascular-disease-focused company
Personnel - Eric Topol, MD, chair of Cleveland Clinic department of cardiovascular medicine, resigns
Personnel - Nereus Pharmaceuticals appoints Dr. Gary Shearman to chairman of the board of directors
Personnel - Vlad Budzynski, MD, PhD, named senior scientist in drug research of MIV Therapeutics
Product Licensing - Forbes Medi-Tech announces Pharmavite contract renewal
Proteomics - Monocyte role in inflammation can be enhanced by C-reactive protein, oxidized LDL combination
Smooth Muscles - p38 MAPK and c-Myc function in aortic smooth muscle cell proliferation
Sociology Research - First myocardial infarction survival rate and socioeconomic circumstances are inversely related
Statins - Simvastatin improves endothelium-dependant dilation after long-term course
Statins - Simvastatin in chronic kidney disease patients exerts anti-inflammatory effect
Statins - Simvastatin withdrawal in hypercholesterolemic patients leaves MMP levels unchanged or reduced
Stem Cell Research - Embryonic stem cells differentiate into cardiomyocytes with functional characteristics
Stents - Researchers report details of new studies and findings in the area of stents
Steroids - Anabolic steroid use increases cholesterol levels, causes liver damage
Stroke - Drug use linked to brain hemorrhage in young adults
Stroke - Recent studies add new data to stroke research
Stroke - Researchers describe findings in stroke studies
Stroke Management - El Camino Hospital earns Joint Commission's "Gold Seal of Approval" for stroke care
Surgical Technology - Arkansas physician develops technique for performing heart catheterizations without x-ray
Surgical Technology - Congenital heart disease lesions were effectively occluded with transcatheter vascular plug
Surgical Technology - Coronary artery bypass grafting vein graft failure markers identified
Surgical Technology - Coronary bifurcation strategies using drug-eluting stents are bench-tested
Surgical Technology - Dural arteriovenous fistula surgery somewhat improved by image-guided neuronavigation
Surgical Technology - Perimembranous ventricular septal defect closure by Amplatzer occluder is safe enough for trials
Surgical Technology - Plaque excision shown to lower amputation rate in patients with critical limb ischemia
Surgical Technology - Restenosis rates were similar for both rapamycin- and paclitaxel-eluting stents
Surgical Technology - Sirolimus stent implantation yields peak drug levels proportional to number of stents implanted
Surgical Technology - Studies advance knowledge in surgical technology research
Tissue Engineering - Tissue engineered cardiovascular patch fabricated for cardiovascular surgery
Transplant Medicine - Animal study shows ETA-RA has protective effect on microcirculation after liver transplant
Transplant Medicine - Norman Shumway, heart transplantation pioneer, dies at age 83
Transplant Medicine - Renal transplant endothelial dysfunction may be a separate process
Type 2 Diabetes - Diastolic dysfunction is linked to anemia in patients with type 2 diabetes
Vaccines Delivery - Data advance knowledge in vaccines delivery research
Venous Thromboembolism - Arixtra shown to reduce patients' risk of venous thromboembolism by 46.7%
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