Pediatric Cancer
Pediatric cancer patients experience endothelial injury caused by anthracyclines
Published in Cardiovascular Week, April 24th, 2006
According to recent research from the United States, "The vascular endothelium plays a central role in the regulation of arterial vasomotor tone, releasing nitric oxide for vasodilation. Endothelial-dependent vasodilation can be assessed in vivo, using high resolution ultrasound to measure changes in diameter of the brachial artery. Animal studies have demonstrated that anthracyclines can damage the endothelium and impair the vasodilatory response of arteries; however, there are no comparable data in humans. This is a pilot study assessing endothelial toxicity from anthracyclines in...
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Source: Cardiovascular Week (2006-04-24)
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