Genetics & Genomics
Cardiovascular disease studied in Hutchinson-Gilford progeria syndrome transgenic mouse model
Published in Cardiovascular Week, April 24th, 2006
Investigators writing in the journal Proceedings of the National Academy of Sciences of the United States of America report, "Children with Hutchinson-Gilford progeria syndrome (HGPS) suffer from dramatic acceleration of some symptoms associated with normal aging, most notably cardiovascular disease that eventually leads to death from myocardial infarction and/or stroke usually in their second decade of life."
"For the vast majority of cases, a de novo point mutation in the...
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Source: Cardiovascular Week (2006-04-24)
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