Kidney Disease
Diastolic dysfunction, abnormal Ca2+ handling may be evidence for uremic cardiomyopathy
Published in Cardiovascular Week, April 24th, 2006
Investigators working in England report, "Cardiovascular disease is the most common cause of death in patients with end-stage renal disease, possibly due to a specific 'uremic cardiomyopathy'. This study investigated the function of the Na+/Ca2+ exchanger in single cardiac myocytes from a model of early renal impairment."
University of London researchers A.C. McMahon and colleagues explained, "Mild uremia was induced by partial...
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Source: Cardiovascular Week (2006-04-24)
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