Cardiovascular Week

Angiology - Successful percutaneous recanalization of chronic total occlusion increases ischemia risk

Atherosclerosis - Complicated plaque of upper thoracic aorta is identified by MR direct thrombus imaging

Cardiovascular Disease - Ischemia is reduced in vascular surgery patients with high-dose beta-blockers, tight HR control

Ischemia - Neurologic spinal cord injury can be prevented by postconditioning

Pediatric Cardiology - Ventricular diastolic stiffness predicts peri-operative morbidity after Fontan procedure

Anesthesia - New approaches and old controversies to pain control after cardiac surgery are focus of review

Angiology - Arteriovenous malformation surgery results in increased microvascular flow

Angiology - Calcium-channel blockers reduce carotid intima-media thickness in hypertension

Angiology - Cardiac surgery lactate levels are not influenced by IL-10 and TNF-beta gene polymorphisms

Angiology - Carotid stenting corrects volume flow comparably to carotid endarterectomy

Angiology - Cerebrovascular delayed in-stent stenosis can spontaneously resolve

Angiology - Emergency percutaneous coronary reintervention may limit extent of myocardial cellular damage

Angiology - Unprotected left main coronary artery stenosis is comparably treated with CABG or PCI

Apoptosis - Apoptotic pathways are differentially affected by temperature upstream of mitochondrial damage

Apoptosis - Cardiomyoblast apoptosis is influenced by insulin-like growth factor

Atherosclerosis - Atherosclerosis in middle age is inversely associated with leg length

Atherosclerosis - Atherosclerotic disease can be detected while screening for abdominal aortic aneurysm

Atherosclerosis - New theory released for cause of atherosclerosis

Atherosclerosis - Serum markers of vascular inflammation in dyslipemia are presented in review

Atherosclerosis - Window into atherosclerosis is afforded by genomic analysis of circulating cells

Business & Finance - Interleukin Genetics reports Q2 revenues of $1.3 million

Business Update - Australia-based Prince Charles Hospital selects Agfa cardiovascular imaging software

Business Update - Avi BioPharma licenses vascular disease program to Cook Group

Business Update - Bioheart acquires rights to technology for acute treatment of heart attacks

Business Update - Cook brings endovascular abdominal aortic aneurysm repair to Japan

Business Update - Covalent Group, Inc. announces $1.7 million contract for Phase 2 clinical trial in atherosclerosis

Business Update - Optometrists' network selects sensor-based blood-pressure measuring devices from Medwave

Business Update - PreMD reports second-quarter results

Business Update - Valentis, Cobra Biologics enter agreement for sale of certain rights, intellectual property

Business Update - VNUS Medical receives U.S. FDA 510(k) clearance to market radiofrequency catheter

Cancer Therapy - Signaling pathway found which transforms otherwise healthy blood vessels into misshapen vasculature

Cardiology - Antitachycardia pacing terminates rapid ventricular tachycardia in patients with ICDs

Cardiology - Aortic valve replacement patient-prosthesis mismatch does not affect survival

Cardiology - Aortic valve replacement should be considered with CABG in certain patients

Cardiology - Atrial fibrillation ablation combined with mitral valve surgery is effective

Cardiology - Atrial fibrillation may be treated with modulation of renin angiotensin system

Cardiology - CABG follow-up chest radiography is associated with a low diagnostic yield

Cardiology - Cardiac surgery patient level of serum EndoCAb is independent predictor of long-term mortality

Cardiology - Cardiomyocyte hypertrophy attenuated by transcription negatively regulation

Cardiology - Cardiopulmonary bypass inflammatory response may be related to a single nucleotide polymorphism

Cardiology - Device closure of the ventricular wall after valved stent implantation is safe

Cardiology - Enoxaparin in patients with acute coronary syndromes increases survival

Cardiology - Factor V Leiden/prothrombin G20210->A mutations do not increase thromboembolic events in women

Cardiology - High-performance bileaflet valve gradients are compared to simulated clinical Doppler measurements

Cardiology - Histone is essential for cardiac myocyte hypertrophy

Cardiology - ICD patients do not require defibrillation threshold reassessment after antiarrhythmic drugs

Cardiology - LV systolic dysfunction after subarachnoid hemorrhage is frequent and usually improves over time

Cardiology - Myocardial ischemia is predicted by exercise-induced QT/RR hysteresis

Cardiology - New guidelines for treatment of heart valve disease lower the age for tissue-valve recipients

Cardiology - Norwood procedure modification is associated with low early mortality

Cardiology - Noxious arousal induces T-wave changes in healthy subjects

Cardiology - Pulmonary vein-atrial junction segments show muscular discontinuities, nerve co-location

Cardiology - Response Biomedical starts clinical trials of test for congestive heart failure

Cardiology - Sex disparities in human cardiac electrophysiology are described on cellular level

Cardiology - Target subunit of myosin phosphatase in heart characterized

Cardiology - Transcatheter closure of patent foramen ovale in older adults prevents recurrent stroke

Cardiology - Women have more bleeding complications after percutaneous coronary intervention than men

Cardiomyocytes - Cardiomyocyte intracellular Zn²⁺ may be key in Ca²⁺ regulation, gene expression signaling

Cardiomyocytes - Classical PKC isoform inhibition relieved negative effects of ET-1 after cardioplegic arrest

Cardiopulmonary Bypass - Early post-cardiopulmonary bypass axillary and tympanic membrane temperatures are unreliable

Cardiovascular Disease - Coronary artery bypass patients with significant LV dysfunction have good medium-term survival

Cardiovascular Disease - Hypertension management in ischemic heart disease is focus of review

Cardiovascular Disease - Multivessel CAD patients gain minimally invasive options with integrated coronary revascularization

Cardiovascular Disease - Posterior leaflet tethering is key in postop mitral regurgitation

Cardiovascular Disease - Transient ischemic LV dilatation on stress echocardiography marks severe coronary artery disease

Cardiovascular Disease - Tricuspid valve repair with an annuloplasty ring results in improved long-term outcomes

Cardiovascular Research - A cup of coffee may trigger a heart attack in at-risk individuals

Cardiovascular Research - Amyloidosis, scarring of pulmonary vein myocardial sleeves is common in elderly

Cardiovascular Research - Changes in HNE-protein thioether adducts were assessed by gas chromatography-mass spectrometry

Cardiovascular Research - Heart failure patients who received follow-up by a nurse in addition to doctor visits had fewer hospitalizations

Cardiovascular Research - Myocardial ischemia-induced arrhythmias are protected against by adrenomedullin via NO, peroxynitrite

Cardiovascular Research - Researchers find a link between autism and abnormal blood-vessel function and oxidative stress

Cirrhosis - High resistin in cirrhosis linked to proinflammatory state but not insulin resistance

Clinical Trials - Coronary disease patients with reduced renal function show lower mortality with trandolapril

Clinical Trials - Inspire terminates phase II clinical trial for platelet aggregation inhibitor

Clinical Trials - Late coronary patency after fibrinolysis for ST-segment elevation MI is improved by clopidogrel

Clinical Trials - Myocardial protection during cardiac surgery is superior with blood vs. crystalloid cardioplegia

Clinical Trials - Paclitaxel-eluting stent benefits are overestimated with mandatory angiographic followup

Clinical Trials - Post-myocardial infarction LV remodeling is not improved with selective MMP inhibitor PG-116800

Clinical Trials - Renin-angiotensin system inhibition in myocardial infarction and heart failure is focus of review

Coronary Artery Bypass - Systematic off-pump coronary artery bypass graft surgery is acceptable alternative to 'on-pump' CABG

Coronary Artery Disease - Stable coronary artery disease receives benefits from coronary collaterals

Critical Care Medicine - Anticoagulation management after mechanical valve replacement is variable

Critical Care Medicine - Endovascular cooling after cardiac arrest improves survival and neurological recovery

Diabetes & Heart Disease - Atorvastatin therapy may not improve cardiovascular end points in type 2 diabetes

Diabetes Complications - Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in diabetes

Diabetes Complications - Microvascular disease in type 2 diabetes linked to lower cerebral blood flow velocity

Diabetes Complications - Nonalbuminuric renal insufficiency in diabetes may be related to increased vascular disease

Diabetes Epidemiology - Diabetes mellitus increased over time among community-dwelling patients with heart failure

Diabetes Pathogenesis - Diabetes promotes cardiac stem cell aging and heart failure; p66^Shc gene deletion prevents them

Diabetes Pathogenesis - Hypoadiponectinemia is not linked to proinflammatory state

Diabetes Pathogenesis - Systolic left ventricular function linked to metabolic control in hypertensive diabetics

Diabetes Pathogenesis - Tumor necrosis factor-alpha induces endothelial dysfunction in prediabetic metabolic syndrome

Diabetes Therapy - Diabetics from Veterans Affairs Diabetes Trial showed better adherence to LDL cholesterol goal

Diabetes Therapy - Edaravone eases hydroxyl radical stress and augmented angiotensin II response in diabetic rats

Diabetes Therapy - Thiazolidinedione treatment reduces subclinical atherosclerosis progression in type 2 diabetes

Diabetic Neuropathy - Epalrestat, an aldose reductase inhibitor, delayed diabetic neuropathy progression

Diagnostics - Acute lung injury diagnosis is supported by early measure of BNP after acute pulmonary edema onset

Diagnostics - ApoAI, ApoB are determined by nanoparticle-based immunoresonance scattering spectral assay

Diagnostics - PCR screening for 22q11.2 microdeletion is aided by new cost-effective assay

Diagnostics - Ventricular aneurysm diagnosis is complicated by ST-segment counterpoise as hypothetical mechanism

Dialysis - Maximal cardiovascular fitness is poor in ambulatory hemodialysis patients

Diet & Nutrition - Nutrigenetics, plasma lipids, and cardiovascular risk are discussed

Diet-Induced Obesity - Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle

Drug Interactions - Erythromycin potentiates PR-interval prolonging effect of verapamil in the rat

Drug Resistance - Clopidogrel response variability and nonresponsiveness are examined in comprehensive review

Electrocardiology - Abnormal intra-QRS potentials are a marker of ischemia-altered ventricular activation

Electrocardiology - Acute left anterior descending coronary occlusion shows upwardly concave ST-segment morphology

Electrocardiology - Anteroseptal myocardial infarction may be simulated by ST-segment distortion by ECG filters

Electrocardiology - Atrial repolarization is observable during the PQ interval

Emergency Medicine - Post-cardiac arrest resuscitation use of therapeutic hypothermia among physicians remains low

Endocrinology - Neuromedin U in paraventricular and arcuate nuclei raises nonexercise activity thermogenesis

Epidemiology - Sex differences in genetic and environmental determinants of pulse pressure are described

Epidermolysis Bullosa - RegeneRx receives grant from U.S. Food and Drug Administration for clinical development of TB4

Epilepsy - Sudden death in epilepsy is characterized in an experimental animal model

Finance - DATATRAK International, Inc. announces second-quarter and first-half operating results

Finance - MedCath updates results due to revised Medicare Disproportionate Share Hospital '05 payments

Finance - Myogen reports second-quarter operating loss of $18.5 million

Finance - NPS Pharmaceuticals reports second quarter and six-month operating results

Finance - Orqis Medical closes $10 million venture debt facility with Lighthouse Capital

Finance - Oscient reports financial results for second quarter and first half of 2006

Finance - Stereotaxis reports record $13.6 million in orders for cardiology device during Q2 2006

Fitness & Wellness - Exercise training improved insulin sensitivity but not glycemic control in type 2 diabetes

Fitness & Wellness - Inflammation markers are inversely related to physical activity and fitness

Gastroenterology - Esophageal acid exposure is generally associated with decreases in autonomic tone

Genetics & Genomics - Basal hepatic and splenic iron status in mice is determined by multiple polymorphic loci

Genetics & Genomics - Genetic testing approach using TBX5 may be mutation screening model for inherited syndromes

Genetics & Genomics - Novel locus is mapped for dilated cardiomyopathy, diffuse myocardial fibrosis, and sudden death

Genetics & Genomics - Postop MI severity is tied to genetic variants in cytokine and leukocyte-endothelial interaction

Healthcare Costs - Blue Cross chooses 15 projects to receive Prevention Minnesota funding

Healthcare Costs - Coronary artery bypass graft risk models based on administrative vs clinical data are compared

Healthcare Costs - Projected costs of stroke in the U.S. top $2 trillion

Healthcare Costs - Prophylactic implantable cardioverter-defibrillator therapy cost-effective

Heart Disease - Fatty acids impair insulin regulation of AMPK and insulin cardioprotection after ischemia

Heart Disease - Post-myocardial infarction healing is promoted by microspheres loaded with angiogenesis protein

Heart Failure - Chronic heart failure drug therapies providing clinical benefit overall do so for the elderly also

Heart Failure - Heart failure mortality risk, but not atrial fibrillation, is reduced by cardiac resynchronization

Heart Failure - Minnesota Heart Failure Criteria can facilitate epidemiologic case-finding for heart failure

Heart Failure - Outcome in chronic heart failure patients is indicated by short-term change in 6-minute walk test

Heart Transplant - Cardiac allograft rejection associated with B and NK cell infiltration

Heart Transplant - Long-term outcome in heart transplantation is predicted by coronary flow reserve

Hematology - Alternatively spliced tissue factor is a previously unknown piece in the puzzle of hemostasis

Hematology - High bleeding rates are not associated with short-term triple therapy among patients undergoing PCI

Hepatitis B Virus - Chronic hepatitis B infection independently predicts diabetic renal outcome

Hunter Syndrome - Idursulfase is effective treatment for Hunter syndrome, clinical trial concludes

Hypercalcemia - Acute myocardial infarction is mimicked by hypercalcemia-induced ST-segment elevation

Hypertension - Central role of the brain in salt-sensitive hypertension is focus of review

Hypertension - Hypertension influences nitric oxide and vascular endothelial growth factor levels in study models

Hypertension - Intracerebral hemorrhage patients treated for acute hypertension show high tolerability

Hypertension - Predix starts Phase II clinical trial for pulmonary hypertension with chronic pulmonary disease

Hypertension - Prehypertension and overweight is common among Israeli adolescents

Hypoxia - Hypoxia-inducible factor functions in transcriptional repression

Imaging - Cardiac C-arm computed tomography affords excellent image quality

Imaging - Coronary plaque tissue characterization offers best potential with optical coherence tomography

Imaging - Myocardial viability was assessed with low-dose dobutamine tissue-tagged MRI with 3D strain analysis

Imaging - Reperfused acute MI assessment by delayed-enhancement MSCT is comparable to MRI and TTC pathology

Imaging - Stented vessel segments are assessed by new real-time 3D quantitative coronary angiography system

Imaging - Total occlusion segment route, calcified plaque distribution can be identified by 16-slice CT

Insulin Resistance - Dexamethasone-induced insulin resistance altered cardiac fatty acid composition and utilization

Ischemia - Ischemia-reperfusion model shows flumazenil mimics but midazolam abolishes ischemic preconditioning

Ischemia - Ischemic tissues accrue benefits from integrin-linked kinase control of neovascularization

Ischemia - Myocardium is preconditioned against ischemia/reperfusion injury by pacing-induced dyssynchrony

Ischemia - Sarcolemmal, mitochondrial K_ATP channels play distinct cardioprotective roles

Ischemic Stroke - Acute ischemic stroke warrants researching the use of recombinant tissue plasminogen activator

Kidney & Cardiovascular Disease - Human vascular smooth muscle cells express a urate transporter

Kidney & Cardiovascular Disease - Vascular disease development, progression is determining mechanism underlying cardiorenal disease

Kidney Disease - Chronic kidney disease and mortality risk are focus of review

Lipid Research - Nicotinic acid and other therapies for raising high-density lipoprotein are focus of review

Medical Devices - Acute massive pulmonary embolism is treated with novel percutaneous catheter thrombectomy

Medical Devices - Fetal blood flow changes can be measured using power Doppler ultrasound

Medical Devices - ICD electrogram analysis method for detecting T-wave alternans is developed