Published in Cardiovascular Week, October 22nd, 2007
"In the present study, we examined whether AGE modification of apolipoprotein A-I (apoA-I) affects its functionality, thus altering its cardioprotective profile. The ability of AGE-modified apoA-I to facilitate cholesterol and phospholipid efflux, stabilise ATP-binding cassette transporter Al (ABCA1) and inhibit expression of adhesion molecules in human macrophages and monocytes was studied. Results The ability of...
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