Cardiology
New findings from University of Toronto, Medical Department describe advances in cardiology
Published in Cardiovascular Week, November 5th, 2007
" Fibronectin, an extracellular matrix protein, is associated with the general process of tissue repair and is present in heart valves. In order to understand the cellular mechanisms of heart valve repair, we hypothesized that fibronectin is produced and secreted by valvular interstitial cells (VICs), and when up-regulated in VICs involved in active repair, it is associated with prominent fibrillar adhesions composed of tensin and alpha(5)beta(1) integrin," investigators in Toronto, Canada report.
"We investigated the interaction of porcine mitral VICs with the underlying fibronectin matrix and the formation and localization of focal and fibrillar adhesion complexes in...
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Source: Cardiovascular Week (2007-11-05)
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