Angiotensins

Reports on angiotensins findings from University Hospital provide new insights

Published in Cardiovascular Week, February 18th, 2008

"We investigated the effect of green tea extract (GTE) in arterial hypertension with high oxidative stress. Angiotensin (Ang) II induces endothelial dysfunction (ED) that is crucial for the development of atherosclerosis and hypertension," scientists writing in the American Journal of Hypertension report.

"Male Sprague-Dawley rats, 13 weeks old, randomly assigned to drinking water with or without GTE (6 mg/mL) received a vehicle, a high (700 mu g/kg/d) or a low (350 mu g/kg/d) Ang II dose for 13 days, by osmotic mini-pumps. Blood pressure (BP) was measured with telemetry. After sacrifice, left ventricular (LV) mass index, small mesenteric artery media-to-lumen...

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Source: Cardiovascular Week (2008-02-18)

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