Cardiology

Research from T. Sulman and co-researchers yields new findings on cardiology

Published in Cardiovascular Week, June 16th, 2008

According to recent research published in the journal Bulletin of Mathematical Biology, "A mathematical model of the cardiomyocyte electromechanical function is used to study contribution of mechanical factors to rhythm disturbances in the case of the cardiomyocyte calcium overload. Particular attention is paid to the overload caused by diminished activity of the sodium-potassium pump."

"It is shown in the framework of the model, where mechano-calcium feedback is accounted for that myocardium mechanics may significantly enhance arrhythmogenicity of the calcium overload. Specifically, a role of cross-bridge attachment/detachment processes, a role of mechanical...

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Source: Cardiovascular Week (2008-06-16)

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