Published in Cardiovascular Week, June 16th, 2008
"Ionic currents were recorded from CHO cells transfected with KCNA5 cDNA with whole-cell patch-clamp technique. The effect of AVE 123 1 on human atrial cell action potentials was explored with a computer model. KCNA5 expression resulted in typical K+ currents that activated and inactivated voltage dependently. Ascending concentrations of AVE1231 (0.1-100 mc M) led to concentration- and...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cardiovascular Week
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.