University of Rochester Medical Center
Study in Circulation provides detail on how low blood flow promotes vascular disease
Published in Cardiovascular Week, July 7th, 2008
Researchers have found the first direct proof that a key protein drives the clogging of arteries in two ways, and that lowering levels of it opens them up, according to study results published in the June edition of the journal Circulation. The work establishes cyclophilin A as an exciting target in the design of drugs against atherosclerosis, the number one cause of heart attacks and strokes, which occur when vessels become completely blocked. While the study was in mice, higher levels of the study protein have also been found in the blood of human patients with diseased blood vessels.
The current results build on three major discoveries in cardiovascular science in...
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Source: Cardiovascular Week (2008-07-07)
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