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Diabetes Animal Studies

Reports from College of Pharmacy, Department of Pharmacology advance knowledge in diabetes animal studies

Published in Cardiovascular Week, August 11th, 2008

New investigation results, 'Effect of telmisartan on cardiovascular complications associated with streptozotocin diabetic rats,' are detailed in a study published in Molecular and Cellular Biochemistry. "Angiotensin receptor blockers provide cardiovascular protection in heart failure patients. We have studied the effect of 8 weeks treatment with telmisartan (5 mg kg(-1) day(-1)) on cardiovascular complications associated with streptozotocin (STZ) diabetic rats," researchers in Ahmedabad, India report.

"Wistar rats were made diabetic with STZ (45 mg kg(-1), iv). Various biochemical and cardiac parameters were measured at the end of 8 weeks. STZ produced...

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