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Alcoholism

Reports from Stanford University, Medical Department highlight recent research in alcoholism

Published in Cardiovascular Week, September 22nd, 2008

"Structural magnetic resonance imaging (MRI) reveals widespread brain damage manifest as tissue shrinkage and complementary ventriculomegaly in human alcoholism. For an animal model to parallel the human condition, high alcohol exposure should produce similar radiologically detectable neuropathology," scientists writing in the journal Alcoholism - Clinical and Experimental Research report.

"Our previous structural MRI study demonstrated only modest brain dysmorphology of the alcohol-preferring (P) rat with average blood alcohol levels (BALs) of 125 mg/dl achieved with voluntary consumption. Here, we tested the hypothesis that wild-type Wistar rats, exposed to...

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