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Gene variation for persons with diabetes associated with increased risk of coronary artery disease

Published in Cardiovascular Week, December 8th, 2008

Patients with type 2 diabetes who have poor glycemic control and a certain genetic variation have an increased risk of coronary artery disease, according to a study in the November 26 issue of JAMA.

Among the known risk factors for cardiovascular disease, diabetes mellitus ranks as one of the most potent. It increases the lifetime risk of a major cardiac event by 2 to 4 times, relative to individuals without diabetes, according to background information in the article. A substantial proportion of cardiovascular risk is under the control of genetic factors.

Genetic variation on chromosome 9p21 has been associated with increased risk of coronary artery...

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