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Ischemia

New findings from College of Medicine describe advances in ischemia

Published in Cardiovascular Week, December 15th, 2008

A report, 'Nitrite consumption in ischemic rat heart catalyzed by distinct blood-borne and tissue factors,' is newly published data in American Journal of Physiology - Heart and Circulatory Physiology. According to recent research from the United States, "Nitric oxide (NO) may limit myocardial ischemia-reperfusion injury by slowing the mitochondrial metabolism. We examined whether rat heart contains catalysts potentially capable of reducing nitrite to NO during an episode of regional myocardial ischemia produced by temporary coronary artery occlusion."

"In intact Sprague-Dawley rats, a 15-min coronary occlusion lowered the nitrite concentration of the myocardial...

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