European Society of Cardiology

Experimental antiarrhythmic drug reduces death rate in patients with atrial fibrillation

Published in Cardiovascular Week, March 16th, 2009

Results from the ATHENA trial, reported in the 12th February issue of the New England Journal of Medicine, suggest that the (as yet unlicensed) antiarrhythmic drug dronedarone can reduce the incidence of cardiovascular-related hospitalisation or death in patients with atrial fibrillation. The study was performed at more than 550 centres in 37 countries.

The trial, with a mean follow-up of 21 months, randomised 4628 patients with atrial fibrillation and at least one other cardiovascular risk factor to either dronedarone or placebo. Results found 24% fewer deaths or hospitalisations (the primary composite endpoint) in the treatment group than in the placebo – a hazard...

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Source: Cardiovascular Week (2009-03-16)

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