Angiotensins
Research from Osaka Medical College, Medical College yields new findings on angiotensins
Published in Cardiovascular Week, May 4th, 2009
"In the present study, the effects of long-term angiotensin (Ang) II antagonism on the development of cardiac and endothelial disorders were examined in Spontaneously Diabetic Torii (SDT) rats. Blood glucose concentration started to increase markedly in the untreated SDT rats from 20 weeks of age, while the blood glucose concentrations of candesartan cilexetil-treated SDT rats were significantly lower until 30 weeks of age," investigators in Osaka, Japan report.
"Cardiac function deteriorated in SDT rats and was accompanied by severe cardiac fibrosis, cardiac hypertrophy, and microstructural pathologic change in cardiomyocytes. Cardiac function was very well preserved...
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Source: Cardiovascular Week (2009-05-04)
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