Angiotensins
Researchers from University of Florida, Medical Department detail findings in angiotensins
Published in Cardiovascular Week, September 7th, 2009
"In spite of recent advancements in the treatment of pulmonary hypertension, successful control has yet to be accomplished. The abundant presence of angiotensin-converting enzyme 2 (ACE2) in the lungs and its impressive effect in the prevention of acute lung injury led us to test the hypothesis that pulmonary overexpression of this enzyme could produce beneficial outcomes against pulmonary hypertension," investigators in the United States report.
"Monocrotaline (MCT) treatment of mice for 8 weeks resulted in significant increases in right ventricular systolic pressure, right ventricle: left ventricle plus septal weight ratio, and muscularization of pulmonary vessels....
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Source: Cardiovascular Week (2009-09-07)
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