Research
Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Published in Cardiovascular Week, December 21st, 2009
The low-density lipoprotein receptor (LDLR) has received a lot of attention because of its connection with coronary heart disease and atherosclerosis, but now it appears as if it may have a beneficial influence in degenerative brain diseases. New research, published by Cell Press in the December 10th issue of the journal Neuron, links LDLR with a reduction in brain changes associated with Alzheimer's disease (AD) and suggests a new therapeutic strategy for this incurable disease.
Amyloid '-protein (A') plays a major pathogenic role in AD, a devastating neurodegenerative disorder characterized by progressive cognitive impairment and memory loss. Accumulation of sticky...
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Source: Cardiovascular Week (2009-12-21)
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