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Medicinal Chemistry

Research conducted at Heinrich-Heine University, Institute of Pharmaceutical and Medicinal Chemistry has provided new information about medicinal chemistry

Published in Cardiovascular Week, April 19th, 2010

Research findings, 'A FRET-based microplate assay for human protein kinase CK2, a target in neoplastic disease,' are discussed in a new report. According to recent research published in the Journal of Enzyme Inhibition and Medicinal Chemistry, "Besides cardiovascular diseases, cancer represents the major cause of death in developed countries. In many different human tumors, increased activity of serine/threonine protein kinase CK2 has been detected, and recent in vivo studies support a direct involvement of CK2 in tumor progression."

"Therefore, potent compounds to decrease CK2 activity to a non-pathogenic level would be a promising effort toward an...

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