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Heart Failure

New heart failure research from Niigata University outlined

Published in Cardiovascular Week, April 19th, 2010

"Experimental autoimmune myocarditis (EAM)-induced heart failure in rats is used to study the pathogenesis of heart failure. Based on a proteomic analysis of soluble (S) and membranous (M) fractions extracted from ventricles of rats with a stable chronic form of EAM-induced heart failure, we assessed changes in protein levels and their correlation to heart functions to gain insights into the pathogenesis and to explore new, targets for the treatment of heart failure," scientists writing in the journal Biological & Pharmaceutical Bulletin report.

"Proteins were separated by two-dimensional gel electrophoresis and silver stained spots were analyzed. In the...

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