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Brugada Syndrome

Findings from Osaka City University, Medical Department advance knowledge in Brugada syndrome

Published in Cardiovascular Week, July 5th, 2010

"Twenty-five patients with BS (7 with documented ventricular fibrillation (VF), 8 with syncope, and 10 without symptoms) and 10 control subjects were paced from the RV apex using 8 beats of drive pacing and a single extra-stimulus. CDs in the right ventricular outflow tract (RVOT) (CD-RV) and in the lateral left ventricle (L-LV) (CD-LV), and the local electrogram durations at a single extra-stimulus in RVOT (D-RV) and L-LV (D-LV) were calculated," investigators in Osaka, Japan report.

"We also evaluated changes in 12-lead ECG parameters in 16 patients with BS after pilsicainide challenge test (Pilsicainide-test). Maximal CD-RV and maximal D-RV were significantly larger...

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