Bradycardia

New bradycardia data have been reported by H.Z. Yuan and co-authors

Published in Cardiovascular Week, November 29th, 2010

2010 NOV 29 -- "We aimed to investigate whether CYP2D6 polymorphisms were associated with the intraocular pressure (IOP)-lowering effect and systemic complications (especially bradycardia) of ophthalmic timolol. One hundred twenty-three primary open-angle glaucoma subjects (123 eyes) were treated with 0.5% aqueous formulations of ophthalmic timolol," scientists in Guangzhou, People's Republic of China report.

"IOP and heart rate were measured before and after timolol administration. DNA was extracted from venous leukocytes of all the subjects. Two single-nucleotide polymorphisms (SNPs) of CYP2D6, for example, rs16947 (2850C >T, R296C) and rs1135840...

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Source: Cardiovascular Week (2010-11-29)

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