Cardiology

Reports from University of Lyon Advance Knowledge in Cardiology

Published in Cardiovascular Week, May 30th, 2011

2011 MAY 30 -- According to recent research published in the American Journal of Physiology - Regulatory Integrative and Comparative Physiology, "The delay tau between rising systolic blood pressure (SBP) and baroreflex bradycardia has been found to increase when vagal tone is low. The alpha(2)-agonist clonidine increases cardiac vagal tone, and this study tested how it affects tau."

"In eight conscious supine human volunteers clonidine (6 mu g/kg po) reduced tau, assessed both by cross correlation baroreflex sensitivity and sequence methods (both P< 0.05). Experiments on urethane-anaesthetized rats reproduced the phenomenon and investigated the...

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Source: Cardiovascular Week (2011-05-30)

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