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Clinical Oncology Week

Susan Hasty, Publisher

Table of Contents . . . May 19th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Clinical Oncology Week | Other Publications

Bladder Cancer - Increasing DNA topoisomerase-II alpha correlates with increasing tumor grade

Meningiomas - Rim enhancement is seen in meningiomas studied with fast FLAIR imaging

Acute Lymphoblastic Leukemia - Stratification of patients by minimal residual disease results may be useful

Chemotherapy - A mathematical model may be useful for cisplatin dosing

Ovarian Cancer - Weekly paclitaxel is effective in recurrent or persistent advanced cancer

Radiation Therapy - Short course radiation for elderly cancer patients is commonly palliative

Acute Myeloid Leukemia - Lower superoxide dismutase activity and radical generation may impact disease

Adrenal Pseudocysts - The solid part of adrenal pseudocysts does not enhance on CT

Anogenital Dermatology - Lichen sclerosus is an autoimmune disorder with increased risk for cancer

Anticancer Drugs - Quaternary ammonium-melphalan conjugate is a potential cartilage targeter

Antimutagenic Foods - Doenjang's active compounds are genistein and linoleic acid

Antitumor Activity - Bortezomib has demonstrated antitumor activity in a variety of tumor types

B-Cell Lymphoma - Large B-cell lymphoma is in remission after eradication of H. pylori

Brain Tumor Diagnostics - Proton magnetic resonance spectroscopy distinguishes brain tumor types well

Breast Cancer - Attachment experiences may play a role in cancer

Breast Cancer - Cyclooxygenase-2 is more highly expressed than in more benign breast diseases

Breast Cancer - Disease progression is associated with increased plasma TGF-beta1

Breast Cancer - Estrogen receptor beta isoforms vary, some are associated with disease

Breast Cancer - MRI was more sensitive than FDG-PET in disclosing malignant breast tumors

Breast Cancer - Mutated TP53 gene status is associated with metastasis, anthracycline resistance

Breast Cancer - No link seen between breast cancer risk and antidepressants

Breast Cancer - Widespread morphoea occurs after radiotherapy for carcinoma of the breast

Bronchial Carcinoma - Treatment of bronchial carcinoma is best assessed by multidisciplinary approach

Cancer Diagnosis - Initiating a dialog is preferable to protecting patients from bad news

Cancer Prevention - Animal and cell line studies have shown chemopreventive activity of tea

Cancer Therapy - Tetrakis((Trishydroxy-methyl)phosphine)gold(I) chloride has antitumor properties

Cerebellar Medulloblastoma - A primitive neuroectodermal tumor by histology had isochromosome 17q

Cervical Disease - Human papillomavirus viral load and HPV16 are associated with high grade lesions

Cervical Lesions - A subset of dysplastic cervical lesions are not detected by the Pap test

Cervical Lesions - Cervicography is more sensitive than PAP test in detecting inflammatory lesions

Cervical Neoplasia - Bacterial vaginosis is not associated with cervical intraepithelial neoplasia

Chemotherapy - Dosage regimen is optimized in cancer chemotherapy using a mathematical model

Colon Cancer Screening - Virtual CT colonography is preferred by patients over conventional therapy

Colorectal Cancer - Alkylphospholipids can open epithelial tight junctions reversibly

Colorectal Cancer - The colon-contrast examination is safe and cost-effective

Colorectal Tumors - MRI is superior to CT in T-staging of rectal cancer and detecting recurrence

Dietary Anticarcinogens - Curcumin has great potential for prevention and therapy of cancer

Endometrial Cancer - Transition from hyperplasia was marked by loss of expression of MLH1 and PTEN

Epstein Barr Virus - T lymphocyte killing of EBV-infected cancer cells increases with E. coli enterotoxin

Estrogen Receptor - A new non-steroidal diphenylnaphthyl propylene ligand is antiestrogenic

Eyelid Tumors - Recurrent solitary reticulohistiocytoma should be considered

Fibrous Histiocytoma - Early radiation-induced malignant fibrous histiocytoma occurs in the oral cavity

Food Additives - Mitogenic stimuli substantially alter susceptibility to chemical carcinogenesis

Gastric Cancer - Work, salt intake, and the development of stomach cancer are associated

Granuloma Annulare - No definite relationship was found between GA and malignant neoplasms

Hepatocellular Carcinoma - Liver transplantation recipients should be selected following different criteria

Herpes Vector -  Herpes simplex virus G47 Delta may be a better anticancer vaccine

Hyperparathyroidism - Minimally invasive parathyroidectomy is better than traditional surgery

Internal Radiation Exposure - Liver cancer risk is higher for Thorotrast recipients than radiation workers

Leukemia - Diagnostic test standardization is needed in pediatric patients for faster cure

Liver Metastasis - Oral 5-FU significantly suppressed primary and metastatic tumor growth

Lymphoma - Monomorphic B-cell lymphoma treated with rituximab after liver transplantation

Malignant Lymphoma - Spontaneous regression of extranodal malignant lymphoma can occur in the gingiva

Melanoma - Metastatic melanoma presents as a cardiac mass and hemobilia

Metastatic Breast Cancer - Combined epirubicin and vinorelbine as first-line therapy was tolerated

Metastatic Melanoma - IL-2 plus interferon-alpha-2a therapy are effective therapeutic strategies

Mouse Sarcoma - Low-dose consecutive CDDP administration would be as effective as bolus CDDP

Mucoepidermoid Carcinoma - Mucoepidermoid carcinoma arises from the eustachian tube and middle ear

Multiple Myeloma - Erythropoietin appears to be beneficial for treatment of associated anemia

Multiple Myeloma - Sickling trait may be associated with an increased risk for multiple myeloma

Myeloma - Transactivation of gp130 by interferon alpha can occur

Natural Antiproliferative - PPAR gamma plus ligand is associated with cell cycle alteration and apoptosis

Oncocytic Tumor - An oncocytic tumor in myoepithelioma arises from the grossopalatine gland

Oral Squamous Cancer - Cisplatin induces apoptosis by apoptosome and mitochondria-mediated pathways

Ovarian Cancer - Family history of ovarian and other cancers increases risk of ovarian cancer

Ovarian Cancer - Neutral endopeptidase/CD10 is expressed in stroma of most tumors except adenoma

Ovarian Tumor - Brenner tumor of the ovary has striking microcystic change

PAP Smear - The new Bethesda 2001 Classification System is simplified

Paget Disease - Serum RCAS1 levels may be valuable as a potential biomarker

Penile Carcinoma - Physical examination is better than ultrasound or MRI in determining tumor size

Pituitary Cancer - Pituitary adenoma is detected on FDG positron emission tomography

Promyelocytic Leukemia - Ginsenoside R93 downregulates activator protein 1 and NF-kappa B activation

Prophylactic Mastectomy - Information and support are needed for women offered prophylactic mastectomy

Prostate Cancer - Long-term data show Zometa slows pain progression and reduces bone complications

Prostate Cancer - Loss of expression of KLF6, a transcription factor, occurs in about 20% of cases

Prostate Cancer - Metastatic disease common, deadly and costly, multicenter study shows

Renal Cancer - Metastatic renal cell carcinoma occurs with pituitary adenoma

Sentinel Node Localization - Radiation risk for hospital staff from procedures and waste stream is minimal

Serous Carcinoma - Serous carcinoma arises in an adenofibroma of the endometrium

Skin Cancer - A simple program greatly improved medical student diagnostic skills

Skin Cancer - CD30+ cells in large primary cutaneous T cell lymphomas are mostly clonal

Skin Cancer - Nicotinamide-containing sunscreens recommended

Squamous Cell Carcinoma - Oral cancer cells but not human epidermal keratinocytes survive in co-culture

T-Cell Lymphoma - Cell proliferation could be selectively reduced by NOS and iNOS blockers

Transplant Medicine - Immunosuppressants affect FAS-mediated activation-induced cell death

Tumor Cell Lines - 2-Amino-3-ethoxycarbonyl-N-(3-methyl-phenyl)-benzo[f]indole-4,9-dione works

Tumor Inhibitors - Isozyme IX is inhibited with aromatic and heterocyclic sulfonamides

Tumor Microenvironment - Cell metabolism is responsible for acidic pH of tumors, not lack of oxygen

Uterine/Ovarian Tumors - Tyrosine kinase inhibitors may not benefit, due to lack of c-kit expression

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