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Clinical Oncology Week

Susan Hasty, Publisher

Table of Contents . . . June 23rd, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Clinical Oncology Week | Other Publications

Pancreatic Cancer - Precursor lesion study should lead to earlier diagnosis and therapeutic options

Proteomics - Ceramide may be important target in antineoplastic strategies

Breast Cancer - The linear quadratic model enabled prediction of tumor response

Lung Cancer - Tumor M2-PK can be used to detect tumor relapse after treatment

Renal Cell Carcinoma - Significant differences in outcome exist in different histologic subtypes of RCC

Anticancer Compounds - Annonacin arrests cancer cells at the G1 phase

Apoptosis - Death receptor signaling and apoptosis is regulated by ceramide

Bone Metastases - Patients with bone complications prefer zoledronic acid over pamidronate

Bone Metastases - Study shows cancer patients benefit from new method of bone analysis

Brain Tumors - Acid-sensing ion channels are present in malignant gliomas

Brain Tumors - Glioma cells are capable of converting CPT-11 to SN-38

Brain Tumors - Perturbation of hyaluronan interactions inhibits malignant properties of glioma

Breast Cancer - Data support role for anastrozole as neoadjuvant therapy

Breast Cancer - Initial findings from NSABP Protocol B-28 presented at oncology meeting

Breast Cancer - Mature survival data confirms fulvestrant as an effective treatment choice

Breast Cancer - Metastatic breast carcinoma to bone is disguised by osteopoikilosis

Breast Cancer - NO targeted within tumor microenvironment could be a feasible treatment

Breast Cancer - Updated phase I data on OncoVEX GM-CSF presented

Breast Cancer - Within individual stages, diagnostic delays had no adverse impact on survival

Cancer Therapy - Fludarabine phosphate and alemtuzumab show promise in treating B-CLL patients

Cancer Therapy - Major results on Eloxatin presented at ASCO

Cancer Therapy - Texaphrins show promise for brain tumor patients

Cell Cycle Progression - Magnetic fields do not influence cell cycle progression in two tumor cell lines

Chemotherapy - Ptquin8 may be a selective anti-telomerase tool for cancer treatment

Colon, Breast Cancer - Labetuzumab, chemotherapy combination yields positive preclinical results

Colorectal Cancer - New study shows diminished risk of cancer relapse

Colorectal Cancer - Phase II study of MGI-114 finds lack of antitumor activity

Corporate Update - Operating plan for 2003 updated by oncology company

Desmoid Tumor - Bone tumor mistaken for chondrosarcoma

Familial Breast Cancer - Individualized coping strategies may prove useful for breast cancer patients

Gallbladder Cancer - Gemcitabine and cisplatin are highly effective in advanced gallbladder cancer

Gallbladder Cancer - The Mayo Clinic regimen is ineffective in advanced gallbladder cancer

Gastric Cancer - Fluorouracil, etoposide, and cisplatin (FEP) is useful in advanced cases

Gene Mutations - R24C mutation of the CDK4 gene is absent in leukemias and solid tumors

Healthcare Staffing - Survey reveals radiation therapy workforce crisis

Hepatocellular Carcinoma - New needle-guide for ultrasound-guided ethanol injection is accurate

Hepatocellular Carcinoma - Prognostic factors for hepatocellular cancer studied in surgical patients without cirrhosis

Hepatocellular Carcinoma - Transcatheter arterial chemoembolization has acceptable toxicity

Hepatomas - Demethylation plays a role in activating type II hexokinase gene expression

Intrapleural Tumor - Intrapleural tumor after video-assisted thoracoscopic surgery

Leukemia - Antithymocyte globulin induces complete remission of hypoplastic leukemia

Leukemia - Results of Phase I leukemia trial presented

Liver Cancer - Thymitaq may improve survival

Lung Cancer - New study suggests monoclonal antibody could help lung cancer patients

Lung Cancer - Palliative thoracic radiotherapy is effective in controlling symptoms

Lung Cancer - Study shows extended survival for lung cancer patients

Lung Cancer - Study shows promise for elderly lung cancer patients

Lymphoma - Lymphoplasmacytoid lymphoma encompasses intra- and extranodal presentations

Lymphoma - Supportive care important for managing acute treatment-related toxicity

Malignant Glioma - Irinotecan activity in malignant glioma is confirmed

Melanoma - Glycosylation has prophylactic effects of on tumor cell interaction

Metastatic Breast Cancer - Docetaxel and vinorelbine are effective in anthracycline-resistant cancer

Mortality - Unemployment has no significant effect on mortality from cancer

Nasopharyngeal Carcinoma - Full-dose concurrent chemoradiotherapy is necessary for better survival

Non-Hodgkin Lymphoma - Many patients who received Bexxar remain in remission

Non-Hodgkin Lymphoma - Zevalin, a radioimmunotherapeutic, shows high response, durable remissions

Oncology - Small hepatocellular carcinoma arises 7 years after successful HCV therapy

Orbital Rhabdomyosarcoma - Rhabdomyosarcoma is an important differential diagnosis in Noonan syndrome

Ovarian Cancer - An increased incidence of ovarian cancer in Japan caused caused by increase in carcinoma

Ovarian Cancer - Tumor cells may remodel their microenvironment to increase their survival

Ovarian and Lung Cancer - Results from phase II trials for ovarian and lung cancer

Pancreatic Cancer - Data reported from study combining TNFerade with chemo and radiation

Pancreatic Cancer - New phase III data from advance pancreatic cancer study

Pancreatic and Biliary Cancer - Gemcitabine, 5-FU show promise for pancreatic and biliary cancer

Paraneoplastic Syndrome - Hypertrophic osteoarthropathy is associated with a metastatic phyllodes tumor

Pediatric Brain Tumors - Small tectal gliomas should be managed conservatively

Pharmacogenomics - Breast cancer foundation questions new pharmacogenomics study

Primary Carcinoid Tumor - A rare primary carcinoid tumor arises in a polycystic kidney

Prostate Cancer - Advances in radiation oncology have led to gains in prostate cancer control

Prostate Cancer - Radiation and surgery provide similar rates of cancer control at 10 years

Prostate Cancer - Study shows age does not affect response to prostate cancer treatments

Prostate Cancer - Tip60 is a protein that may be involved in cancer development and recurrence

Prostate Cancer - Uniform guidelines for reporting prostatic needle biopsies helps clinicians

Spondylodiscitis - Unspecific spondylodiscitis follows anastomotic leakage after rectal resection

Stomach Cancer - Study shows survival benefits for stomach cancer patients

Testicular Cancer - Overall survival in stage I disease is 98.6% and cause-specific survival is 100%

Thyroid Cancer - Imaging should localize metastases to propose more therapeutic options

Transhepatic Portography - The right anterior caudal oblique projection is best for preoperative staging

Tumor Metastasis - Hypoxia promotes tumor invasion

Uterine Tumor - A rare uterine neoplasm resembles an ovarian sex cord tumor

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