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Esophageal Cancer

High-dose radiation combined with Nedaplatin and 5-FU is a safe and effective

Published in Clinical Oncology Week, August 18th, 2003

High-dose radiation combined with Nedaplatin and 5-FU is a safe and effective.

"From January 1999 to November 2000, a total of 24 esophageal cancer patients (17 untreated and seven recurrent cases) were treated with radiation therapy (60-70 Gy) combined with cis-diammine-glycolatoplatinum (Nedaplatin) (80-120 mg/body) and 5-fluorouracil (5-FU) (500-1,000 mg/body/24 h, continuous infusion for 5 days)," researchers in Japan report.

"Grade III leukocytopenia was observed in six (25%) of the patients. Grade III and IV thrombocytopenia was observed in one patient each," wrote K. Nemoto and colleagues, Tohoku University, School of Medicine.

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