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Lymphoproliferative Disease

Reduced-intensity BEAM-alemtuzumab SCT effective

Published in Clinical Oncology Week, March 29th, 2004

Reduced-intensity BEAM-alemtuzumab stem-cell transplantation is safe and effective for patients suffering from lymphoproliferative disorders.

In a recent study, hematologists in England evaluated the results of "reduced-intensity allogeneic stem-cell transplantation using BEAM-alemtuzumab conditioning (carmustine, etoposide, cytosine arabinoside, melphalan, and alemtuzumab 10 mg/d on days -5 to -1) in six United Kingdom transplant centers."

"Sixty-five patients with lymphoproliferative diseases underwent sibling (n=57) or matched unrelated donor (n=8) transplantation," explained R.D. Faulkner and coauthors at Nottingham City Hospital.

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