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Glioma

Brain cancer gene identified

Published in Clinical Oncology Week, April 5th, 2004

Researchers have identified a gene that may be involved in the development of certain aggressive brain tumors.

Gliomas are the most common type of brain tumor. Around 1500 new cases are diagnosed every year in the United States. Most will die within the following year. The growth of the tumor and its blood supply may be regulated by the potential tumor-suppressor gene ING4, reported Igor Garkavtsev and colleagues from Harvard Medical School in Nature. Human glioma tissue contains less ING4 than does normal control tissue, and the extent of the reduction correlates with the progression from lower to higher grades of tumors.

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