Breast Cancer

Angiogenesis gene linked to biomarkers of tumor-cell growth

Published in Clinical Oncology Week, April 19th, 2004

Johns Hopkins Kimmel Cancer Center scientists have made what is believed to be the first link between a gene that controls blood vessel growth and increased activity in a panel of breast cancer biomarkers that regulate tumor cell growth.

They announced their findings at the 95th Annual Meeting of the American Association for Cancer Research.

The HOXB7 (or homeobox B7) gene is thought to drive tumor development by increasing the production of growth factors that affect blood vessel development, or angiogenesis. The team of Kimmel Cancer Center researchers, led by Saraswati Sukumar, PhD, professor of oncology, found increased production of messenger...

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Source: Clinical Oncology Week (2004-04-19)

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