Tumor Growth

Protein critical in tadpole metamorphosis has role in human cancer

Published in Clinical Oncology Week, April 19th, 2004

There's something magical about tadpoles. The mere mention of this little creature sparks happy memories of children screaming with delight as they splash in a shallow stream trying to capture some of the tiny swimmers in a cup. The real magic happens as the children witness the metamorphosis from tadpole to frog.

Within the mystery of this transformation is a biological series of changes that among other things, allows one appendage to be shed while four others sprout from the tadpole's body. Before a tadpole becomes a frog, it must lose its tail. A time-lapse video of this process would actually reveal that the tadpole tail doesn't simply fall off but rather grows...

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Source: Clinical Oncology Week (2004-04-19)

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