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Clinical Oncology Week

Susan Hasty, Publisher

Table of Contents . . . November 22nd, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Clinical Oncology Week | Other Publications

Bladder Cancer - Study shows COMBIDEX aids in diagnosis of metastatic lymph nodes

Breast Cancer - Disease and therapy can result in thoracic changes

Cervical Cancer - Plasma HPV DNA may be useful to monitor therapy and disease progression

Oncogenesis - Adenoma to carcinoma hTR expression not linked to promoter methylation

Prostate Cancer - Luteinizing-hormone-releasing-hormone causes prostatic atrophy

Acute Myelogenous Leukemia - Phenotypic karyotype markers identified in AML with t(8;21)

Air Quality - Smoke-free workplace laws provide protection impossible to achieve otherwise

Blood Banking - SC refrigeration is simple option for autotransplants within few days of harvest

Bone Marrow Transplantation - Psychosocial/behavioral variables do not effect 1-year survival after BMT

Breast Cancer - Fruits, vegetables may decrease some women's risk of ER-positive cancer

Breast Cancer - Higher serum relaxin levels associated with metastatic disease

Breast Cancer - Meta-analysis finds glutathione S-transferase M1 status a potential risk factor

Breast Cancer - More testing methods OK'd to select patients who may benefit from Herceptin

Breast Cancer - New protein associated with aggressiveness in breast and ovarian cancer

Breast Cancer - New technique detects microcalcifications more reliably

Breast Cancer - Wife of Senator Edwards undergoes tests to determine breast cancer treatment

Breast Cancer Therapy - 111In-DTPA-trastuzumab suitable for clinical use

Breast Cancer Therapy - Celecoxib and alpha-TEA shows promise as combination therapy

Business & Finance - Biopharmaceutical company announces third quarter 2004 results

Business & Finance - Company reports Q3 results, provides initial FDA guidance on DX-88 Program

Business & Finance - Pharma company reports improved financial results

Business & Finance - Pharma company reports third quarter 2004 financial results

Business & Finance - Pharmaceutical company reports financial results

Business Update - Elekta expands open systems commitment with new sales consulting agreement

Business Update - Four board members named and new center opened by cancer support group

Business Update - Oncology IT solutions provider expands European radiation oncology business

Cancer & Fertility - Lance Armstrong's former wife summons the courage for her own race

Cancer Genetics - BRCA1/2 tests available, but ethics, economics restrain use in France

Cancer Immunology - Phage-based microarrays useful for humoral immune analysis

Cancer Proteomics - Cancer-altered metabolism linked to cytochrome c oxidase subunit variation

Cancer Research - Cancer-killing activity of gene-based INGN 241 therapy in tumors identified

Cancer Research - Drug used to stabilize vessels, block cancer cells from leaving bloodstream

Cancer Research - Pharma companies move to next phase of collaboration on cancer targets

Cancer Research - Pharma company provides Tarvacin IND update

Cancer Research - Study sheds light on how poxviruses can jump from species to species

Cancer Therapy - Biopharmaceutical, MGI Pharma announce Dacogen MAA accepted for review by EMEA

Cancer Therapy - Boston study shows experimental cancer drugs getting safer

Cancer Therapy - Company initiates phase I clinical trial for XL999

Cancer Therapy - Engineered stem cells can home in on tumors and deliver drug payload in mice

Cancer Therapy - Licensing agreement forged to market aniemetic for chemotherapy patients

Cancer Therapy - Patent granted for production and processing of the reovirus

Cancer Therapy - Pharma company announces completion of recruitment for skin tumor trial

Cancer Therapy - QUADRAMET data presented at Prostate Cancer Foundation scientific retreat

Cancer Therapy - Scientists find key to unlock body's own cancer defense

Cancer Therapy - Stem cells ferry concentrated anticancer drug to tumors

Cancer Therapy - Substance may improve cancer immune therapy, vaccines

Cancer Vaccine - Biotech receives patent allowance for nonlethal hemocyanin extraction method

Cardiomyopathy - Animal model systems have increased knowledge of myopathic muscle physiology

Cell Biology - Initial sensor for p53 tumor-suppressing pathway identified

Cervical Cancer - Irinotecan plus nedaplatin with rhG-CSF shows therapeutic promise

Cervical Cancer - SELDI MS plus proteomics scoring distinguishes cancerous from normal cervix

Cervical Cancer - Study: No justification for colposcopy in screening of young women

Cholesterol - Data demonstrates the efficacy of CRESTOR in treating elevated cholesterol

Chronic Lymphocytic Leukemia - Utility of antibody-based CLL treatments reviewed

Clinical Trials - Investigational new drug application for cancer drug approved by U.S. FDA

Collaborations - ComGenex, partner, expand their drug-discovery collaboration

Collaborations - Companies collaborate on oncology market research

Colon Cancer - Brochure helps explain treatments for colorectal cancer

Colon Cancer - Enhanced aspirin holds promise as colon cancer preventive agent

Colon Cancer - Model suggests higher mortality for virtual colonoscopy

Colon Cancer - Obese women face higher risk of colorectal tumors

Colon Cancer - Study reveals genetic link to colon cancer

Colon Cancer - Targeted therapy + efficient chemotherapy increases colorectal cancer survival

Colorectal Cancer - Excessive alcohol intake plus low folate increase risk of colorectal cancer

Complementary & Alternative Medicine - Studies suggest green tea/tea polyphenols lower cancer risk/inhibits tumors

DNA Research - Role of XPC protein in cellular response to cisplatin treatment clarified

Dermatology - Apaf-1 may sensitize human cutaneous melanoma to cancer therapy

Diagnostics - Nanogen introduces diagnostic testing and diagnostic development platform

Drug Development - Anti-CEA antibody T84.66 humanized

Drug Development - Cancer-focused company reports atomic structure of c-KIT in complex with Gleevec

Drug Development - Evogene to evaluate plant-based production of therapeutic protein candidates

Endometrial Cancer - Height, obesity, and activity level associated with cancer risk

Environmental Health - A long wait for Love Canal health study that promises no answers

Fibrosarcoma - Tumor reoxygenation compared after carbon-ion and X-ray irradiation

Finance - Biopharmaceutical company reports third quarter financial results

Finance - Cancer research company reports improved third quarter results

Finance - Net Q3 income allocable to ORACEA-maker stockholders of $0.05 per share

Finance - Pharmaceutical company reports third quarter results

Finance - TF decoy technology company reports Q3 results

Gene Mutations - Diagnostic lab offers new gene sequencing service for mutation detection

Gene Mutations - Gene mutations alter myocardial performance via changes in Ca2+ sensitivity

Granular Cell Myoblastoma - Genetic profile of granular cell tumors determined

Head and Neck Cancer - Global gene expression profiles determined in HNSCC tumor lines

Heart Failure - Heart failure may be accentuated by a downregulation of myocardial TNF-alpha

Hepatitis - Hepatitis study information presented at conference

Hypogonadism - Europe approves STRIANT for testosterone replacement in hypogonadal men

Imaging - Lesion evaluation tool receives FDA clearance

Immunizations - Study indicates vaccine protects against cervical cancer

Information Technology - 3D imaging software company signs agreement to integrate CT colon CAD technology

Information Technology - Cancer institute installs research, management software system

Information Technology - Henry Ford Health System adopts digital imaging system

Leukemia - Antiviral therapy for adult T cell leukemia lymphoma is promising

Leukemia - Nippon Shinyaku Co., Ltd. receives approval to market TRISENOX in Japan

Leukemia - Obesity increases older women's risk of acute myelogenous leukemia

Leukemia - Orphan drug designation granted for the treatment of leukemia

Leukemia - U.S. FDA grants orphan drug designation to acute myelogenous leukemia drug

Leukemia Therapy - Guidelines to define therapeutic strategies for leukemia described

Liver Cancer - RFA safe for treating liver tumors pushing on GI tract

Lung Cancer - Biotechnology company receives grant to create lung cancer therapies

Medical Devices - NYU Cancer Center features new hyperthermia system

Medical Training - New curriculum seeks to standardize training of cancer physicians worldwide

Medicare - Coverage expansion proposed for cancer patients

Mental Heath - Family therapy reduces stress symptoms in adolescent survivors of cancer

Neuroblastoma Therapy - Microtubule alterations identified in drug-resistant tumor cells

Non-Hodgkin Lymphoma - BEAM with only cytokine support effective in high-risk patients

Oncology - Bcl-xL gene overexpression boosts breast cancer lymph node metastasis

Oncology - Clinical trials announced for inhaled cancer pain medication

Oncology - Cyclooxygenase-2 expression aligns with transitional cell carcinoma invasion

Oncology - Disulfiram combats melanoma metastasis

Oncology - Genetic counselors and advocacy group develop genetic discrimination brochure

Oncology - KL-6 is a serological marker for liver cancer in patients with hepatitis C

Ovarian Autotransplantation - Doctors transplant ovary to woman's arm to preserve her fertility

Ovarian Cancer - Inhibitory protein involved in cancer cell apoptosis and cisplatin sensitivity

Ovarian Cancer - Second-line therapy of advanced disease with GnRH analogs shows promise

Pediatric Cancer - Nongenetic causes are most likely risk factors for childhood cancer development

Pediatric Leukemia - Donor characteristics/herpesvirus exposure impact survival in pediatric leukemia

Pediatrics - Specialists' call on European Union to improve childhood cancer treatment

Personnel - BioSciences company adds to scientific advisory board

Personnel - Biopharma company names senior vice president of sales and marketing

Personnel - Charles Theuer, MD, PhD, named VP of clinical research, CMO of biotech company

Personnel - Guenter Schirmer, MD, named medical director by drug developer

Personnel - John E. Ezcurra named director of manufacturing by oncology-focused company

Personnel - Wade Sexton, MD, joins Genitourinary Oncology Program at Moffitt cancer center

Prostate Cancer - Blocking gene opens avenues for treating prostate cancer

Prostate Cancer - CB7630 phase I data presented at Prostate Cancer Foundation scientific retreat

Prostate Cancer - Foundation announces Coffey award recipients for commitment to prostate cancer

Prostate Cancer - Postoperative radiotherapy improves progression-free survival

Pulmonary Fibrosis - Anticancer drug to fight fatal lung disease

Radiation Therapy - Troxerutin can protect non-malignant tissue from radiation damage

Radiotherapy - GENEPI could be tool to refine and fine-tune treatment for cancer

Radiotherapy - Increased investment in radiology will improve cure rates for cancer patients

Renal Cell Carcinoma - Patient enrollment commences for IMOxine phase II trial in renal cell carcinoma

Skin Cancer - New study examines skin protection in children

Skin Cancer - Researchers discover potential skin cancer prevention target

Small Cell Lung Cancer - Cancer therapeutics development company files IND for small cell lung cancer

Stem Cell Transplantation - Multiagent strategy lowers regimen-related toxicity in children undergoing HSCT

Stem Cells - Cancer center doctor receives $25,000 award for research

Type 2 Diabetes - CuraGen, partner advance investigational compound for diabetes

Ventricular Morphology - Na+/K+-ATPase alpha1B1 is required for cardiomyocyte morphology

Women's Health - FDA approves noninvasive procedure to treat uterine fibroids

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