Clinical Oncology Week
Susan Hasty, Publisher
Table of Contents . . . April 11th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Clinical Oncology Week | Other Publications
Cancer Prognosis - Increased stromal versican related to higher lung tumor recurrence rate
Cervical Cancer - Abdominal radical trachelectomy is a fertility-preserving option for some cases
Cervical Cancer - Nonsurgical options available to treat HPV-related disease
Esophageal Cancer - Positron emission tomography of esophageal cancer prevented unnecessary surgery
Neuroblastoma - Human neuroblastoma cell growth inhibited by CAY10404
Actinic Keratosis - Clinical trial for non-melanoma skin cancer and actinic kertosis initiated
Adenocarcinoma - Researchers study possibility of recombinant human prolactin for immunotherapy
Angiolipoma - Angiolipoma is not a metastatic tumor or a malignant vascular tumor
Biological Therapies - Enamel matrix derivative inhibited breast cancer cell attachment to bone
Biomedical Research - LC column for separating protein samples for biomarker research introduced
Bone Marrow Cancer Diagnostics - Proposal of morphologic bone marrow response score for imatinib treatment in CML
Breast Cancer - Researchers detail new studies and findings in the area of breast cancer
Bone Marrow Cancer Therapy - Production of TGF-beta1 and IFN-gamma linked to regeneration of hematopoiesis
Bone Marrow Transplantation - BMT successful in a patient with c-mpl-mutated CAMT from carrier donor
Brain Cancer - Brain tumor related to GSTM1 null genotype but not with GS771 or GSTP1 variants
Brain Cancer - Quantitative RT-PCR diagnosed carcinoembryonic antigen mRNA in cancer patient
Breast Cancer - 5F 203 induces NF-kappa B activity in drug-sensitive breast cancer MCF-7 cells
Breast Cancer - Adjuvant treatment for node-positive breast cancer approved in Europe
Breast Cancer - Researchers publish new studies and findings in the area of breast cancer
Breast Cancer - Breast cancer linked to second hand smoke
Breast Cancer - Cardiac death after radiation for breast cancer dramatically down, study shows
Breast Cancer - Enzyme expression ratio is a prognostic indicator in tamoxifen-treated patients
Breast Cancer - Epidemiologic, clinical similarities seen in African and African American women
Breast Cancer - Evidence-based medicine screened for likelihood of sentinel lymph node biopsy
Breast Cancer - Findings in breast cancer provide new insights
Cancer Therapy - Studies add new findings to cancer therapy body of knowledge
Breast Cancer - Hazard rates of recurrence following diagnosis of primary breast cancer examined
Breast Cancer - Microarray analysis can identify etiologic agent
Breast Cancer - Minimal residual disease persists in bone marrow after adjuvant therapy
Breast Cancer - Minimal risk of macrometastases in the NSLN in breast cancer patients
Breast Cancer - Minimum, expected, and maximum detection rates calculated for England and Wales
Breast Cancer - Patients with inducible NOS-positive breast carcinomas had lower survival rate
Oncology - Researchers provide details of new studies and findings in the area of oncology
Breast Cancer - Patients with negative node biopsy and no axillary dissection were cancer free
Breast Cancer - Study to compare partial and whole breast radiation
Breast Cancer - Tobacco smoke and smoking increases risk in premenopausal Japanese women
Business & Finance - Pharmaceutical company announces third quarter financial results
Oncology - Researchers publish new studies and findings in the area of oncology
Business & Finance - Pharmaceutical company reports unaudited results for 4th quarter, full year 2004
Business Update - Biotechnology companies broaden antisense drug development partnership
Business Update - Biotechnology companies partner to commercialize research products
Business Update - Imaging technology provider announces change to CD-Ratiometer agreement
Business Update - Oncology-focused pharmaceutical company ends proposed acquisition of Synt:em
Business Update - Pharma company retains Piper Jaffray & Co. as strategic advisor
Oncology - Studies describe new findings in oncology research
Cancer Cell Evasion Mechanism - Tumor cells evaded immune system by downregulating antigen processing
Cancer Drugs - Doxorubicin and cisplatin chemotherapy used in spindle cell sarcomas of the bone
Cancer Drugs - Efficacy, safety, and steady-state pharmacokinetics of MS Contin XL reviewed
Cancer Pain Management - Historical overview of cancer pain management researched
Cancer Research - Anti-cancer therapy product found to enhance effect of leading cancer drug
Cancer Research - Avastin licensed for use in combination with chemotherapy in England
Cancer Therapy - Arsenic use endorsed in leukemia therapy
Cancer Therapy - Artemisinin-tagged holotransferrin affected cancer cells
Cancer Therapy - Cancer patients with viral hepatitis benefit from hepatic artery chemotherapy
Cancer Therapy - Company reports 67% decrease in metastatic nodules with CTCE-9908
Cancer Therapy - Inhibition of tumor-derived CCL5 also inhibited metastasis of 4T1
Cancer Therapy - Localized radiation treatment directly to site improves cancer treatment
Cancer Therapy - Online pharmacy cosponsors cancer treatment program in Japan
Cancer Therapy - Phase II trial of cancer drug GCAN 101 to start in Israel
Cancer Therapy - Recent studies add new data to cancer therapy research
Cancer Therapy - Revlimid exceeds expectations in relapsed, refractory myeloma
Cancer Therapy - Stories of cancer pain shared
Cancer Therapy - Study shows clear improvement in survival demonstrated for glioblastoma
Cancer Therapy - Sustained response noted in patient with bifrontal glioblastoma multiforme
Cancer Therapy - The G-quadruplex-interactive molecule BRACO-19 inhibited tumor growth
Cell Biology - DNA "packaging" linked with cancer
Cell Biology - Scientists identify new model of NK cell development
Cervical Cancer - Enriched HPV-specific polyclonal T cells may be key to future immunotherapies
Cervical Cancer - Radical hysterectomy unnecessary for adequate treatment of early stage disease
Cervical Cancer - Three-year screening interval okay for HIV+ women negative for HPV
Chemotherapy - Researchers examine rhIL-11 for use in children with solid tumors or lymphomas
Chemotherapy - Update on agents utilized for perioperative intraperitoneal chemotherapy
Colon Cancer Treatment - Staging in colon cancer optimized by using sentinel lymph node biopsy
Colorectal Cancer - For African Americans, screening should begin at 45, not 50
Dental Research - Therapeutics company develops new candy to counteract tooth decay
Diagnostics - Swallowed pill-sized video camera is new esophagus disease diagnostic tool
Diagnostics - UPAR may identify breast cancer patients with a risk for micrometastasis
Disease Associations - California report conclusively links secondhand smoke, breast cancer
Disease Associations - No relationship found between ovarian cancer risk and incomplete pregnancy
Drug Delivery - EHDA produces nearly monodispersed drug release particles
Drug Delivery - Viruses could deliver HIV, malaria, rabies and cancer vaccines as pills
Drug Development - Milestone reached in antibody-drug conjugate agreement with Genentech
Eczema - FDA published advisory regarding Protopic and Elidel
Embryonic Stem Cell Research - ESCs differentiate and myelinate after spinal cord transplantation
Endometrial Cancer - Risk in postmenopausal women with asymptomatic endometrial polyps is low
Eye Cancer Therapy - Bendamustine chemotherapy as second-line treatment in metastatic uveal melanoma
Eye Cancers - BRAF mutations detected in conjunctival but not uveal melanomas
Finance - Biopharmaceutical company reports 2004 year-end financial results
Finance - Cancer therapeutics development company announces financial results
Finance - Cancer-focused pharmaceutical company reports 2004 financial results
Finance - Cancer-focused technology company announces $4.7 million financing
Finance - Humanized antibodies developer announces improved financial results
Finance - Nanotechnology company updates shareholders on recent developments
Finance - Oncology company reports fourth quarter and year end financial results
Finance - Pharma company announces financial results with tripled profit after tax gains
Finance - Pharmaceutical company announces delay in filing 10-K
Finance - Pharmaceutical company reports fourth quarter and year-end results
Finance - U.S. government funds cancer program to train investigators
Follicular Lymphoma Diagnostics - Lack of Bcl-2 expression in follicular lymphoma caused by mutations
Gastric Cancer - Case of gastric tumor of the Carney triad reported
Gastroenterology - Thymidine phosphorylase has differential effects in the tumor microenvironment
Gene Research - Adipose differentiation-related protein shows clear-cell renal cancer status
Glioblastoma Multiforme - FDA approves TEMODAR (temozolomide) for patients with newly diagnosed GBM
Glioma - U.S. FDA approves use under IND of monoclonal antibody in child with glioma
Graft-Versus-Host Disease - Antilymphocyte/thymocyte globulins reduce acute/chronic GvHD incidence/severity
Gynecology - Matrilysin uses progelatinase to generate ovarian cancer cell invasion
HIV/AIDS Vaccine - Diagnostics company announces result of China contracts for HIV and TB tests
HIV/AIDS-Related Tumor - Cardiac tumor was initial manifestation of AIDS
Head & Neck Cancer - Supracricoid hemilaryngopharyngectomy in patients with squamous cell carcinoma
Head and Neck Cancer - CD105 microvessel density marks the prognosis of squamous cell carcinoma
Head and Neck Cancer - Endostatin diminishes angiogenic activity in squamous cell carcinoma
Head and Neck Cancer - Findings describe new data in head and neck cancer research
Health Promotion - New educational information for colorectal cancer patients available online
Healthcare Coverage - National survey shows causes for delay by lesbians in obtaining health care
Imaging - Physicians promote use of in-office imaging to Congress
Imaging - Researchers look into novel PET radiotracers
Imaging - Technology company announces consulting agreement, acquisition of patent
Immunology - Antitumor immunosurveillance can be unmasked by removal of regulatory components
Immunology - Researchers examine vaccine strategies against MUC1-expressing tumors
Immunotherapy - Researchers characterize breast cancer patient-derived dendritic cells
Infection Management - Management of infectious agents in oncology outlined
Information Technology - Cancer-focused biopharmaceutical company selects business management system
Information Technology - Information technology co. provides electronic data capture for clinical trial
Leukapheresis - SC mobilization influences CD34+ cell collection efficiency of leukapheresis
Leukemia - ATL cells express sufficient antigens to evoke T cell responses in vivo
Leukemia - Geographic patterns and pathogenetic implications of IGHV gene usage in leukemia
Leukemia - HLA-G expression is linked with an unfavorable outcome in lymphocytic leukemia
Leukemia - Treatment and survival of adults with acute leukemia in the Primorsky Region
Liver Cancer - Lower incidence of intrahepatic recurrences via resection than radiofrequency
Liver Cancer - Molecular mechanisms of Fenretinide clarified
Lung Cancer - Benefits of lung cancer screening with CT questioned
Lung Cancer - Clinical pathway plotted by evidence-based medicine for lung cancer chemotherapy
Lung Cancer - Data published on nanoparticle delivery of mda-7 in lung cancer
Lung Cancer - Detection of CK19 mRNA by RT-PCR in MLNS associated with increased recurrence
Lung Cancer - Patient enrollment complete in trial of Xcytrin for lung cancer brain metastases
Lung Cancer Tumorigenesis - Rare Met proto-oncogene juxtamembrane variations linked to tumorigenesis
Lymphoma - CVP chemotherapy combined with rituximab improves patients' outcomes
Lymphoma - TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
Lymphoma Diagnostics - T-bet expressed in Hodgkin's lymphoma and might be useful as a diagnostic marker
Medical Devices - Long-term benefit of drug delivery device after breast cancer surgery shown
Melanoma - CD4+ and CD8+ lymphocytes monitoring during therapy helps prognostic abilities
Melanoma - Imiquimod shows promise for topical treatment of lentigo maligna
Melanoma - Marker for new blood vessel formation in tumors discovered
Melanoma - Novel melanoma antigen FCRL/FREB is immunogenic in multiple melanoma patients
Melanoma - Researchers present system to investigate CD4-dependent anti-tumor mechanisms
Melanoma - Sentinel node biopsy recommended as prognosticator for lymphadenectomy
Melanoma - Targeting mutant B-Raf protein reduces melanoma development
Melanoma Diagnostics - Role of preoperative ultrasonography in reducing number of SLN biopsies examined
Melanoma Therapy - Mofarotene inhibited melanoma cell motility
Mergers & Acquisitions - Biopharma company acquires assets of Savetherapeutics A.G.
Mergers & Acquisitions - Intellectual property of German biotech Savetherapeutics AG acquired
Nasopharyngeal Cancer - U.S. FDA grants 510(k) clearance for applicator for brachytherapy treatments
Neuroectodermal Cancer - Transcriptional silencing of DLC-1 might contribute to tumorigenesis
Non-Small Cell Lung Cancer - Avastin plus chemotherapy extends survival in first-line non-squamous NSCLC
Oncogenesis - Laser detection of cancer cells also may improve understanding of stem cells
Oncogenic Osteomalacia - Fibroblast growth factor 7 plays a role in mediating oncogenic osteomalacia
Oncology - Carcinoid tumors should be treated in specialized centers
Oncology - Dominant B cell epitope from NY-ESO-1 may be a potential biomarker
Oncology - Gene expression profiles of papillary thyroid cancer are easily identified
Oncology - Gene-loaded dendritic cells kindle a response to breast cancer antigens
Oncology - Genes predispose breast cancer patients to tamoxifen-induced fatty liver
Oncology - Neutrophils raise hepatocyte growth factor levels in non-Hodgkin lymphoma
Oncology - Reports advance knowledge in oncology research
Oncology - Ultrasound morphology of varying types of breast cancer must be differentiated
Oncology - VEGF is a strong prognostic indicator for breast cancer
Oncology - VEGF-A and VEGFR-2 correlate with tamoxifen response in breast cancer patients
Ovarian Cancer - Clinical trial of monoclonal antibody seeks patients with advanced disease
Ovarian Cancer - Reports add new data to ovarian cancer research
Pancreatic Cancer - Increased expression of betaTRCP1 associated with chemoresistance
Pancreatic Cancer - New therapies needed for treating ductal pancreatic adenocarcinoma
Pancreatic Cancer - Raltitrexed and gemcitabine not recommended for patients with pancreatic cancer
Patents - Company issued patent for human factor 5A genes, 2 others for agricultural use
Patents - DNA-focused company announces issuance of patent on gene delivery technologies
Patents - Pharmaceutical company agrees to settle patent interference action
Patents - Test to predict genetic predisposition to poor metabolism of drugs wins patent
Patents - U.S. Patent granted for nucleic acid-based technology for immune modulation
Pediatric Cutaneous Melanoma - Early diagnosis depended upon recognition that this disease affects the young
Personnel - Pharma company announces management promotions
Personnel - Rudi E. Moerck hired as consultant by cancer-focused pharmaceuticals company
Personnel - Thomas W. Burke, MD, named executive VP, physician-in-chief at M.D. Anderson
Pituitary Cancer - Case of acromegaly caused by pituitary adenoma discussed
Pituitary Gland Diagnostics - Dynamic magnetic resonance imaging diagnosed lesions adjacent to pituitary gland
Post-Irradiation Sarcoma - Rare case of post-irradiation sarcoma after external beam radiation therapy
Prostate Cancer - Device company announces data in study of prostate cancer treatment
Prostate Cancer - Dietary lycopene and other carotenoids may protect against prostate cancer
Prostate Cancer - Dipeptidyl peptidase defeats the malignant phenotype of prostate cancer cells
Prostate Cancer - Doctor completes 50th treatment with minimally invasive prostate cancer therapy
Prostate Cancer - Insomnia studied in men treated with radical prostatectomy for prostate cancer
Prostate Cancer - Scientists find new prostate cancer suppressor gene
Prostate Cancer - U.S. CMS issues coverage determination for Abarelix
Prostate Cancer Diagnostics - Current practice of Gleason grading among genitourinary pathologists revealed
Prostate Cancer Therapy - Androgen deprivation therapy influenced metabolism of prostate cancer patients
Quality of Life - Diagnostic criteria fail to identify psychological suffering in oncology
Quality of Life - Reliability and construct validity of SF-36 in Turkish cancer patients reviewed
Radiation Therapy - Curcumin improves skin wound healing in irradiated mice
Radical Prostatectomy - Alpha-blocker therapy and cystography not needed for early catheter removal
Radiotherapy Side Effects - Phase III pilot study of dose escalation using radiotherapy in prostate cancer
Rectal Cancer Diagnostics - Magnetic resonance predicted T-staging of rectal cancer with moderate accuracy
Renal Cell Cancer - Expression of Ksp-cadherin distinguished renal carcinoma from renal oncocytoma
Sarcoma Diagnostics - Divergent phenotype in malignant soft tissue cancers might complicate diagnosis
Sarcoma Treatment - Treatment strategy for epithelioid sarcoma of the hand reviewed
Skin Cancer - Alterations of mtDNA in malignant melanoma not induced by UV radiation
Skin Cancer - Early age at onset might predict CDKN2A mutation in Liguria, Italy
Soft Tissue Cancers - Myxoid MFH and pleomorphic liposarcoma shared very similar genomic imbalances
Squamous Cell Carcinogenesis - Expression of FHIT in squamous cell cancer and premalignant lesions of larynx
Stem Cell Research - Low-dose total body irradiation causes clonal fluctuation of stem cells
Stem Cell Transplantation - Cord blood better than haploidentical mobilized PBL for sustained engraftment
Stem Cell Transplantation - NST yields durable response in minority of metastatic renal cancer patients
Stem Cell Transplantation - Positive CMV serology may contribute to neurological complications after HSCT
Stem Cell Transplantation - Rituximab effective for refractory autoimmune cytopenias after ASCT
Stem Cell Transplantation - Stable engraftment achieved in unrelated/mismatched SCT in mucopolysaccharidosis
Stem Cell Transplantation - Two partially HLA-matched cord blood units enhance engraftment
Stem Cell Transplantation-Related Infection - Aspergillus+ blood cultures not always assoc. with invasive disease in SCT
Stem Cell Transplantation-Related Infection - Preemptive ganciclovir for CMV disease post-ASCT cost-effective/reduces toxicity
Stomach Cancer - Abnormal E-cadherin expression associated with gastric cancer
Stomach Cancer - Carcinogenesis potential predicted by analyzing RUNX3 expression topographically
Thyroid Cancer - Aurora B overexpression associated with thyroid cancer
Thyroid Cancer - Benign Hurthle cell adenoma mimicked oncocytic papillary thyroid carcinoma
Thyroid Cancer - Bone involvement is high in advanced medullary thyroid cancer
Thyroid Cancer - Environmental agents linked to thyroid cancer development
Thyroid Cancer - Silencing of tumor suppressor ARHI contributed to thyroid carcinogenesis
Tobacco Use - Houston agency to continue secondhand smoke public education
Tobacco Use - Tobacco industry cast doubt on link between smoking and p53 mutations
Tonsil Cancer - Tonsillar metastasis revealed signet-ring cell carcinoma of the rectum
Tumorigenesis - Tumor warning in blood explained
Vaccine Development - Ineffective spontaneous antitumor T cell responses can be reawakened
Vaccine Development - Scientists examine how dendritic cells process recombinant antigens
Vaccine Development - Scientists look at simian virus 40 potential for cancer vaccination
Vaccine Development - Telomerase vaccine study results in metastatic prostate cancer patients released
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