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Colorectal Cancer

FOLFOX improved convenience in untreated metastatic colorectal cancer patients

Published in Clinical Oncology Week, May 16th, 2005

A modified schedule of FOLFOX was shown to improve convenience for Australian patients with untreated metastatic colorectal cancer.

"This study determined the efficacy and safety of a modified FOLFOX regimen that improved patient convenience without compromising oxaliplatin dose intensity. A total of 62 patients with previously untreated metastatic colorectal cancer were enrolled to receive, entirely as outpatients, 2-weekly cycles of oxaliplatin 100 mg/m2 i.v. over 2 h, together with leucovorin 400 mg/m2 over 2 h, 5-fluorouracil (5-FU) 400 mg/m2, bolus, followed by a 46-h infusion of 5-FU at 2.4 g/m2," scientists reported in...

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