Susan Hasty, Publisher
Table of Contents . . . June 20th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Clinical Oncology Week | Other Publications
Breast Cancer - Benefits of aspirin continue to astound
Central Venous Access - Low complication rates reported with Cathlink 20 device
Lung Cancer - Registration of FDG-PET and planning CT images resulted in greater consistency
Metronidazole - Topical formulation containing metronidazole alleviated wound odor and exudate
Ovarian Cancer - Dyspnea occurred during thalidomide treatment for advanced ovarian cancer
Acute Myeloid Leukemia - Wnt/beta-catenin pathway involved in acute myeloid leukemia pathogenesis
Amoxicillin - Amoxicillin interaction with DNA in human lymphocytes studied
Anemia - Cochrane Review Group and Blue Cross/Blue Shield set up ASH/ASCO guidelines
Angiology - New platforms afford opportunities to explore myofibroblast invasion
Apoptosis - Galactocerebrosidase and galactosylcerebroside metabolism linked to cancer cells
Breast Cancer - New findings in the area of breast cancer described
Apoptosis - Vectors encoding apoptin or E4orf4 produce temporary tumor killing
Atherosclerosis - Fluorescence device diagnoses atherosclerosis and tumors
Bacteriology - Biotech company offers product for removal of endotoxins
Biological Therapy - Understanding tumor suppressive mechanisms of SCs may lead to cancer therapies
Bladder Cancer - Bladder preservation strategies discussed
Blood Diseases - Rare occurrence of hematologic malignancies in the retroperitoneum
Breast Cancer - New findings in the area of breast cancer detailed
Bone Cancer - Cartilaginous tumors characterized with Tl-201 scintigraphy
Bone Cancer - Osteosarcoma cells respond differentially to tumor suppressor gene therapy
Bone Cancer - Recent findings in bone cancer provide new insights
Bone Marrow Transplant - High autopsy rates maintained in Canadian blood and marrow transplant program
Brain Cancer - Phase 2 trials of targeted agent to treat primary brain cancer 'shows promise'
Brain Cancer - TRF1 expression loss marks astroglial tumor progression
Breast Cancer - Recent studies add new data to breast cancer research
Breast Cancer - Baylor, company identify new genes in breast cancer
Breast Cancer - Breast-conserving surgery compared to mastectomy as primary treatment modality
Breast Cancer - Companies sign reseller agreement to offer CAD system to low volume facilities
Breast Cancer - Diagnostics company updates NMP66 protein program for breast cancer detection
Breast Cancer - Differing preoperative chemotherapy regimens were compared
Breast Cancer - Dosing of phase 1 clinical trial for taxane TPI 287 for breast cancer initiated
Breast Cancer - Reports describe recent advances in breast cancer research
Breast Cancer - Effect of NSAID use on cancer risk needs more study
Breast Cancer - Efficacy of aprepitant for preventing chemotherapy-induced nausea and vomiting
Breast Cancer - Findings advance knowledge in breast cancer research
Breast Cancer - High efficacy and low toxicity of weekly docetaxel treated breast cancer
Breast Cancer - Home-based intervention increases survivors' physical activity
Breast Cancer - Link between ICAM1 gene and breast cancer metastasis reported in published study
Breast Cancer - Research add new data to breast cancer body of knowledge
Breast Cancer - More protection from early breast cancer recurring with letrozole, study shows
Breast Cancer - New data confirm early start of anastrozole may prevent breast cancer recurrence
Breast Cancer - Patient accrual completed for dose dense Abraxane study
Breast Cancer - Researchers provide details of new studies and findings in the area of breast cancer
Breast Cancer - Synaptotagmin implicated in human breast cancer
Breast Cancer - VEGF-D has direct and indirect effects on breast carcinoma cell proliferation
Business & Finance - New treatments will grow chronic myelogenous leukemia drug market, report says
Cancer Therapy - Reports add new data to cancer therapy research
Business Update - Pharma company announces restructuring
Cancer Epidemiology - Cancer is major cause of childhood death in developing countries
Cancer Metastasis - Peritumoral macrophages produce YKL-40 in lung cancer patients
Cancer Metastasis - Platelet factor 4 gene transfection prevents tumor-associated vessel formation
Cancer Risk Factors - Somatic hypermutation is not a cause of chronic hepatitis C-linked lymphoma
Cancer Surgery - Buccal mucosal transposition flap suitable for oral defect repair
Cervical Cancer - Researchers describe findings in cervical cancer studies
Cancer Therapy - 2-Methoxyestradiol staunches angiogenesis at clinically achievable doses
Cancer Therapy - Children need better cancer drugs, says expert panel
Cancer Therapy - Company issues update on lapatinib
Cancer Therapy - Data show drug's potential to treat metastatic melanoma, renal cell carcinoma
Cancer Therapy - Efficacy of therapy for follicular lymphoma confirmed
Cancer Therapy - Inhaled drug offers new cancer option
Oncology - Researchers' data advance oncology research
Cancer Therapy - NRAS gene suppression initiates melanoma cell apoptosis
Cancer Therapy - New lung cancer research presented at ASCO
Cancer Therapy - Oral compound may replace intravenous chemotherapy after surgery, data show
Cancer Therapy - PTEN gene therapy treats prostate cancer alone and with other agents
Cancer Therapy - Phase I results of KOS-953 as multiple myeloma therapy presented
Cancer Therapy - Photodynamic therapy stimulates COX-2 release from cancer cells
Oncology - Researchers' work adds to oncology body of knowledge
Cancer Therapy - Recent findings illuminate research in cancer therapy
Cancer Therapy - Risks outweigh benefits of shark cartilage as anticancer treatment
Cancer Therapy - Rituximab sends rare hepatic marginal zone B-cell lymphoma into remission
Cancer Therapy - p53 cancer vaccine sensitizes tumors to platinum, taxane chemotherapies
Cancer Treatment - Article provides guidelines for the prevention of CAD in cancer patients
Oncology - Studies describe new findings in oncology research
Cancer Treatment - Report describes characteristics of cardiomyopathy from cancer therapies
Cancer Vaccines - Human anti-globulin antibody responses to antibodies reviewed
Cancer Vaccines - Reports describe recent advances in cancer vaccines research
Carcinogenesis - Carcinogen-DNA adducts formed in mammary cells treated with benzopyrene
Carcinogenesis - Transcriptional signatures of benzo[a]pyrene in mammary cells reported
Cardiology - Aortic valve papillary fibroelastoma analyzed
Ovarian Cancer - Researchers' data advance ovarian cancer research
Cardiomyopathy - Dexrazoxane prevented cardiomyopathy in pediatric cancer patients
Cervical Cancer - Automation-assisted screening effective in Finnish public health trial
Cervical Cancer - CT-based volumetric calculations compared to ICRU reference-point estimates
Cervical Cancer - Data advance knowledge in cervical cancer research
Cervical Cancer - Maryland to require insurance coverage of HPV tests in cervical cancer screening
Cervical Cancer - ORI-1001 antisense oligonucleotide stifles human papillomavirus replication
Chemotherapies - Docetaxel and celecoxib inhibited non-small cell lung cancer
Chemotherapies - Induction chemotherapy and radiation compared to concurrent chemoradiotherapy
Chemotherapy-Induced Anemia - Data: Aranesp dosed every 2 weeks is comparable to Epoetin alfa dosed weekly
Chemotherapy-Induced Neuropathy - New NAALADase inhibitor data in chemotherapy-induced neuropathy presented
Chronic Lymphocytic Leukemia - FDA clears CLL trials for inhibitor drug GRN163L
Chronic Myelogenous Leukemia - CML progenitor cells identified with hemangioblastic characteristics
Clinical Trials - Antimetastatic activity of novel mechanism-based gelatinase inhibitor explored
Clinical Trials - Clinical data on hyaluronic acid in combo with other drugs published
Clinical Trials - Clinical trial results of drug in prostate, ovarian, breast cancer presented
Clinical Trials - Company reports early results in clinical trial of drug combination for NSCLC
Clinical Trials - Preliminary phase 1 clinical data on oncology oral HDAC inhibitor drug announced
Clinical Trials - Results of clinical pharmacology study of paclitaxel product presented
Clinical Trials - Trial in older cancer patients suggests benefits of drug plus chemotherapy
Collaborations - Clinical trials agreement signed for oncology research
Colon Cancer - Blockade of Wnt-1 signaling induced apoptosis in human colorectal cancer cells
Colon Cancer - Effects of irradiation on adhesion molecules in colon cancer cells examined
Colon Cancer - Efficacy of irinotecan and raltitrexed as first-line treatment in colon cancer
Colon Cancer - Genetic counseling anticipated for hereditary nonpolyposis colorectal cancer
Colon Cancer - Global fibrinolytic capacity increased in metastatic colorectal cancer
Colon Cancer - Susceptibility of colon cancer and rectal cancer to environment analyzed
Colon Cancer - Tissue microarray used to characterize macrophage populations
Colorectal Cancer - Clinical significance of serum CEA protein and CEA mRNA examined
Colorectal Cancer - Interleukin-4 gene transduction drives antitumor efforts in mice
Colorectal Cancer - Serum CEA level correlated to metabolic volume as determined by FDG-PET
Critical Care Medicine - Cancer patients requiring mechanical ventilatory support were characterized
Dermatology - Americans continue risky behaviors despite skin cancer warnings
Dermatology - Dermatologists urge the public to be smart in the sun
Dermatology - Osteopontin encourages melanoma growth and invasion
Diagnostics - Collaborating companies reach milestones in cancer diagnosis system development
Doxorubicin - Chronic progressive cardiac dysfunction linked to doxorubicin therapy for ALL
Drug Development - Data on erythromycin-based therapy for gastrointestinal disorders presented
Drug Development - Final data presented on ADH-1 phase I trial
Drug Development - First clinical trial of oral AP23573 initiated
Drug Development - IGN101 reduces disseminating tumor cells in patients with epithelial cancers
Drug Development - Interim data presented on toxicity, response from phase III trial of Neovastat
Drug Development - Phase II cancer trial results published
Drug Development - Phase III metastatic melanoma trial studying Sorafenib initiated
Drug Development - Positive data reported from phase II trial of GVAX vaccine for leukemia
Drug Development - Positive phase II results with CoFactor in colorectal cancer reported
Drug Development - Researchers' data advance drug development research
Drug Development - Scientists demonstrate new way of fighting antibiotic resistance
Drug Development - U.K. grants Clinical Trial Authorization for cancer drug
Drug Resistance - New polysaccharide may help combat multidrug resistance in cancer
Endocrinology - High-grade neuroendocrine carcinoma of the ampulla of Vater analyzed
Enzymology - Matrix metalloproteinase-1 confers resistance to lamin-based degradation
Enzymology - Tyrosine kinase inhibitor PTK787 overpowers angiogenesis and liver cancer
Epstein-Barr Virus - Cancer risk of gastric corpus linked to Epstein-Barr virus infection
Femoral Neck Cancer - Case of femoral neck tumor reported
Femoral Neck Fracture - Fracture of the femoral neck linked to risk of serious underlying pathology
Finance - Diabetes management company reports first quarter 2005 financial results
Flavonoids - Dietary bioflavonoids induced apoptosis in human leukemia cells
Ganglioneuroma - Protein expression in neuroblastoma and ganglioneuroma studied
Gastric Cancer - Chemosensitivity testing done with highly purified tumor cells using MTT assay
Gastric Cancer - DNA hypermethylation of tumor-related genes in gastric carcinoma studied
Gastric Cancer - Feasibility of sentinel node concept in gastric carcinoma assessed
Gastric Cancer - Gastric cancer diagnosed after eradication of Helicobacter pylori
Gastroenterology - Cytokeratin touted as superior marker for detecting biliary tract carcinoma
Gastroenterology - MALT lymphoma case of the colon identified as simple mucosal discoloration
Gastroenterology - Oral A-EE788 discourages colon cancer metastasis using a dual approach
Gene Research - DNA analysis product shows more sensitivity for detecting human papillomavirus
Gene Research - Genetic markers separate glioblastoma multiforme subtypes
Gene Silencing - Inducible transcription systems based on the H1 promoter push RNA interference
Gene Therapy - Strategies to enhance tumor visibility improve cancer immunotherapy
Gene Transfer - Researchers' work adds to gene transfer body of knowledge
Genetic Testing - Genetic testing conducted in families of male BRCA1/2 carriers and non-carriers
Gliomas - Diffusion tensor imaging used in preoperative evaluation of tumor grade
Gynecology - Diagnostic accuracy of FDG-PET imaging for detecting gynecologic cancer analyzed
Gynecology - Fractionated stereotactic radiotherapy used as surrogate to brachytherapy boost
Gynecology - Reports describe recent advances in gynecology research
Gynecomastia - Efficacy and tolerability of radiotherapy for gynecomastia investigated
HDAC Inhibitors - Novel HDAC inhibitors with radiosensitizing properties
HIV/AIDS Healthcare - Endoscopic findings comparable between Asian/Western symptomatic HIV patients
HIV/AIDS-Associated Kaposi Sarcoma - Generic HAART reduces viral load to undetectable in AIDS-associated KS patients
HIV/AIDS-Associated Neoplasia - Anal intraepithelial neoplasia prevalent in HIV-infected men
Head and Neck Cancer - Nasopharyngeal cancer tumor growth declines upon COX-2 inhibition
Head and Neck Cancer - Overexpressed S100A2 is implicated in esophageal cancer progression
Head and Neck Cancer - Response of head and neck cancer patients to radiotherapy evaluated via FDG-PET
Hematology - Recent findings illuminate research in hematology
Hepatectomy - Living donor hepatectomies safely performed in Jehovah Witnesses
Hepatic Tumors - Uncommon liver tumors occur primarily in women, center reports
Hepatocellular Carcinoma - Elevated endostatin/collagen XVIII associates with liver cancer progression
Herpes Simplex Virus - Herpesvirus designed to enter malignant glioma cells characterized
Hodgkin Lymphoma - Involvement of Waldeyer's ring in Hodgkin lymphoma clarified
Home Healthcare - Pressure ulcers developed in patients receiving home hospice care
Hormones - Docetaxel prescribed to men experiencing increased prostate-specific antigen
Human Papillomavirus - Factors linked to cervical cancer in HPV-16-positive women reported
Information Technology - Oncology database of cancer registries for marketing available
Information Technology - Prostate cancer center selects storage system for clinical research archives
Intracranial Tumors - Complication rates after gamma knife radiosurgery calculated
JC Virus - JC virus DNA sequences detected in brain tumors of pediatric patients
Kidney Cancer - Kidney cancer cell lines exhibited great sensitivity to patupilone
Leukemia - Arsenic trioxide circumvented multidrug resistance in human leukemia cell lines
Leukemia - Farnesyltransferase inhibitors implicated in acute myeloid leukemia
Leukemia - Long-term efficacy, safety, and leukemogenic potential of anagrelide examined
Leukemia - Researchers detail new studies and findings in the area of leukemia
Liposarcoma - Gains of 13q correlated with poor prognosis in liposarcoma
Liver Cancer - Chromosome studies link genes to hepatitis B-related hepatocellular carcinoma
Liver Cancer - Progress reported in liver cancer trials of light infusion treatment with drug
Lung Cancer - Concurrent radiation, chemo, followed by surgery lengthens lung cancer survival
Lung Cancer - Infections in non-small cell lung cancer patients treated with radiotherapy
Lung Cancer - Interim seliciclib phase IIa data reported at 2005 ASCO
Lung Cancer - Preliminary phase 2 study results show improved progression in NSCLC patients
Lung Cancer - STELLAR trial investigator reports on 2 phase 3 studies of lung cancer compound
Lymphoma - Genetic aberrations occurred in primary cutaneous large B-cell lymphoma-A
Lymphoma - Impact of epoetin-beta therapy on survival of patients with lymphoma assessed
Melanoma - Drug developer announced initiation of phase II PI-88 anticancer product trial
Melanoma - Genasense phase III results in malignant melanoma updated at ASCO
Melanoma - Vaccine targets tumors where they live
Melanoma Vaccine - Peptide vaccine induces prolonged relapse-free interval in melanoma
Melanoma Vaccines - New findings in the area of melanoma vaccines detailed
Mergers & Acquisitions - Investments company completes Gen ID acquisition, appoints new directors
Motexafin Gadolinium - Motexafin gadolinium disrupted zinc metabolism in human cancer cell lines
Myeloma - Bortezomib combined with dexamethasone to treat patients with multiple myeloma
Natural Products - The legume by-product 4-0-methylgallic acid blunts angiogenic activity
Neoplasia - FISH analysis of hematological neoplasias defined a cluster on chromosome 1
Neutrophils - Immature neutrophils mediated tumor cell killing via IgA
Oncogenesis - Uterine 3-methylcholanthrene exposure triggers overexpressed oncogene hWAPL
Oncology - Antiangiogenic immunotherapy targets signals that fortify cancer growth
Oncology - Chemokine CXCL14 is a potent dendritic cell chemoattractant
Oncology - Glypican-3 diagnoses human cancers and could be targeted for tumor prevention
Oncology - Hyperbaric oxygen exposure produces few unintended effects in treated tumors
Oncology - Researchers publish new studies and findings in the area of oncology
Oncology Research - Maintenance therapy with chemotherapy doubles lymphoma patients' remission time
Osteosarcoma - Clinical data demonstrates activity of Quadramet in osteosarcoma
Otorhinolaryngology - Horizontal partial laryngectomy treated supraglottic squamous cell carcinoma
Ovarian Cancer - Conservative treatment employed in epithelial ovarian cancer
Ovarian Cancer - Consolidative abdominopelvic radiotherapy treated epithelial ovarian cancer
Ovarian Cancer - Reports describe recent advances in ovarian cancer research
Paclitaxel - In vitro interaction between paclitaxel and oxaliplatin examined
Paclitaxel - Phase I study of paclitaxel and doxifluridine therapy in gastric cancer patients
Pancreatic Cancer - Bcl-X-L protein levels determined apoptotic index in pancreatic carcinoma
Pancreatic Cancer - Findings on immunotherapy anticancer drug for pancreatic cancer published
Pancreatic Cancer - Neuropilin-1 regulates the growth of human pancreatic adenocarcinoma cells
Pancreatic Cancer - Qualitative and quantitative measurements used to predict pancreatic pathology
Papilloma - Histological features and transformation of inverted papilloma characterized
Patents - Seventeenth patent granted to biotech company
Patents - U.S. patent granted for betulinol derivatives being developed as cancer therapy
Personnel - Steven J. Mento appointed to board of directors by DNA-focused research company
Personnel - Technology investment company appoints new CEO
Pharmacokinetics - Pharmacokinetics of gemcitabine and pemetrexed in patients with solid tumors
Philanthropy - Foundation says 47.5 million Livestrong cancer support wristbands sold in year
Postoperative Complications - Hypomagnesemia occurred after major abdominal operations in cancer patients
Preventive Medicine - Senate bill would fund research to detect, prevent, treat, cure mesothelioma
Product Licensing - Radiofrequency ablation company signs license agreement with EMcision Limited
Prognostics - Clinical impact of metastatic lymph node ratio in gastric cancer examined
Prostate Cancer - Body mass index affects total and complexed PSA levels in men
Prostate Cancer - Crystal structure of prostate-specific membrane antigen determined
Prostate Cancer - Data from KRX-0401 single-agent phase II study presented at meeting
Prostate Cancer - Enlarged prostate drug allows for less invasive prostate biopsies
Prostate Cancer - FDG-PET shows promise as outcome measure
Prostate Cancer - High-dose regions linked to likelihood of cure after prostate brachytherapy
Prostate Cancer - Incidence of prostate cancer in Sicily projected
Prostate Cancer - MUSE urethral suppository erectile dysfuncation trial results presented
Prostate Cancer - New test for early detection of prostate cancer shows promise
Prostate Cancer - Noninvasive prostate cancer treatment available soon in South Africa
Prostate Cancer - Obesity is risk factor for aggressive prostate cancer
Prostate Cancer - Protein markers with PSA levels useful in predicting prostate cancer recurrence
Prostate Cancer - Results announced in phase II study of Provenge in early-stage prostate cancer
Prostate Cancer - Sonablate 500 pan-European medical center study launched
Prostate Cancer - Study finds prostate cancer in 25% of high-risk men with "normal" PSA levels
Proteomics - Researchers detail new studies and findings in the area of proteomics
Pulmonary Medicine - Uteroglobin constructs block COX-2 expression in lung cancer cells
Radiation Sensitivity - Antiviral activity of Cidofovir improved radiation sensitivity in head and neck
Rectal Cancer - Cases of arterio-ureteral fistula reported
Rectal Cancer - Company gets FDA okay to resume phase II trial in rectal cancer with TNFerade
Rectal Cancer - Effect of CCRT in locally advanced low rectal cancer after radical resection
Rectal Cancer - Survival after preoperative radiotherapy in rectal carcinoma analyzed
Renal Cancer - Antisense blockade of FGF-2 restrains renal cancer endothelial cell migration
Renal Cancer - Bcl-2 inhibition improves the effects of renal cell carcinoma chemotherapy
Renal Disease - Genetic patterns classify renal tumor subtypes
Skin Cancer - Dermatologist offers advise on precautions to help prevent skin cancer
Skin Cancer - Family physician visits aided in early recognition of melanoma
Soft Tissue Sarcoma - Histological vascular invasion identified as risk factor for distant metastasis
Spermatogenesis - CAG repeat length measured in infertile male population of Irish origin
Stem Cell Research - New York foundation awards $50 million to 3 institutions for stem cell research
Stem Cell Transplantation - AHSCT evaluated in children with acute lymphoblastic leukemia
Stem Cell Transplantation - Antibody responses to H-Y minor mHAs correlate with GVHD and disease remission
Stem Cell Transplantation - Researchers report details of new studies and findings in the area of stem cell transplantation
Surgical Complications - Complication of Bricker ileal conduit urinary diversion reported
Thyroid Cancer - Overexpressed genes identified in thyroid oncocytic adenomas
Thyroid Cancer - Value of morphometry in fine-needle thyroid aspirate analysis clarified
Tumorigenesis - EBAG9 identified as prognostic factor for renal cell carcinoma
Urothelial Cancer - GSTA1 associated with susceptibility to urothelial cancer in Japanese
Uterine Papillary Serous Carcinoma - Pap smear useful in cytomorphological tumor analysis
Vector Delivery - Aurintricarboxylic acid reinforces intratumoral non-viral gene transfer
Virology - Pseudotyped retroviral vectors kill cancer and augment suicide gene therapy
Virology - Researchers describe findings in virology studies
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