Published in Clinical Oncology Week, June 27th, 2005
"FA is a genetically heterogeneous chromosomal instability syndrome associated with multiple congenital abnormalities, aplastic anemia, and cancer. We report that a deletion mutation in the FANCGgene (c.637_643delTACCGCC) was present in 82% of FA patients in the black populations of Southern Africa," investigators in England reported.
"These patients originated from South Africa, Swaziland, Mozambique, and Malawi. The mutation was found on the same haplotype and was present in 1% of controls from the black South African population," explained N.V. Morgan...
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