Lymphoma

Lymphoma-associated chromosomal abnormalities detected by FISH

Published in Clinical Oncology Week, July 18th, 2005

Lymphoma-associated chromosomal abnormalities could easily be detected by fluorescence in situ hybridization (FISH).

"FISH is useful for detecting specific chromosomal abnormalities in various tumors. In lymphomas, diagnosis is frequently made using paraffin wax embedded tissue," scientists in Spain reported.

"However, FISH performed under these conditions presents potential technical problems and difficulties in interpretation. To show that FISH using tissue imprints and cytopreps or alternatively, bone marrow (BM) smears, constitutes an easy and rapid strategy to overcome these constraints. The study comprised 46 patients with lymphoma," explained...

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Source: Clinical Oncology Week (2005-07-18)

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